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Parkinson's disease

A brain disorder that slowly worsens, mainly affecting movement.

Compared within 6 studies that had both: 339 people with Parkinson's and 274 healthy people. 8 microbes are less common in people with Parkinson's, and 12 more common.

A difference is an association: it doesn’t mean these microbes cause, prevent or treat Parkinson's.

Phylum

Searching opens both lists and shows only matching rows.

Less common in Parkinson's · 8

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Blautia wexlerae in 6 studies Healthy 98% Parkinson's 88%
  2. Roseburia inulinivorans in 6 studies Healthy 82% Parkinson's 70%
  3. Fusicatenibacter saccharivorans in 6 studies Healthy 93% Parkinson's 84%
  4. Intestinibacillus sp. Marseille-P6563 in 6 studies Healthy 5.2% Parkinson's under 1%
  5. Streptococcus australis in 6 studies Healthy 17% Parkinson's 8.3%

More common in Parkinson's · 12

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Streptococcus mutans in 6 studies Healthy 1.7% Parkinson's 9.1%
  2. Bifidobacterium dentium in 6 studies Healthy 9.4% Parkinson's 20%
  3. Ligilactobacillus salivarius in 6 studies Healthy 2.3% Parkinson's 8.6%
  4. Cloacibacillus evryensis in 6 studies Healthy 6.0% Parkinson's 15%
  5. Streptococcus anginosus in 6 studies Healthy 2.4% Parkinson's 8.3%

As many carry these · 1 the amount differs

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Ruthenibacterium lactatiformans in 6 studies Healthy 81% Parkinson's 84%

    Carriers have slightly more, in 6 of 6 studies (0.11% → 0.13% of their gut microbes).

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China, Finland, the United States.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 524 microbes

Compared within studies that had both, but not listed above.

Studies disagree · 2

No meaningful difference · 522
PubMed · human studies and reviews first

Recent research

All research on it
  1. Randomized trial Journal of ethnopharmacology · 2026
    The adjunct use of Bifidobacterium animalis subsp. lactis BAMA-B06/BAu-B0111 improves the therapeutic efficacy of Liuwei'anxiao Capsule in alleviating constipation in Parkinson's Disease: A randomized controlled study.
    PubMed ↗
  2. Review Microbiological research · 2025
    Akkermansia muciniphila: A double-edged sword in life-stage-specific nutritional modulation of Parkinson's disease via the gut-brain axis.
    PubMed ↗
  3. Review Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
    Microbiota-brain interaction: The role of gut-derived proteins in addressing various neurological disorders including Parkinson's (PD) and Alzheimer's diseases (AD).
    PubMed ↗
  4. Observational Scientific reports · 2025
    Elevated Lactobacillus salivarius and genus Akkermansia in fecal samples of Taiwanese patients with parkinson's disease and diabetes mellitus.
    PubMed ↗
  5. Randomized trial Movement disorders · 2025
    Effects of a Four-Strain Probiotic on Gut Microbiota, Inflammation, and Symptoms in Parkinson's Disease: A Randomized Clinical Trial.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 85 linked papers, last 10 years