Plate · Actinomycetota
species · NCBI 1680

Bifidobacterium adolescentis

Its ID gene (16S) · each bar is one letter A C G T NCBI 16S
What's this?
Zoomed in: letters 115–138
  1. G
  2. G
  3. G
  4. C
  5. T
  6. T
  7. G
  8. A
  9. G
  10. T
  11. G
  12. C
  13. G
  14. G
  15. T
  16. A
  17. G
  18. G
  19. G
  20. G
  21. A
  22. G
  23. A
  24. C

Its ID gene: the stretch scientists read to tell microbes apart. Each bar is one letter of its DNA. Every species has its own order of letters, so the pattern works like a fingerprint. Close relatives share most of it.

16S rRNA gene, V4 region: the 253 letters between the standard primers (515F/806R), which are the same in every species. One reference sequence; strains can differ by a letter or two. NCBI NR_074802.2

Formerly Bifidobacterium faecale.

Healthy guts53%
Samples10,367
Products13
Genome · 2.1 million letters · 59% G+C
Shortest we have Mycoplasmoides genitalium 0.6M
⋮ 347 shorter
Bifidobacterium adolescentis 2.1M
Bifidobacterium average 2.3M
⋮ 2,004 longer
Longest we have Bradyrhizobium altum 9.8M

Small for a gut microbe: longer than 15% of the 2,354 we have genomes for.

59% G+C, higher than 73% of gut microbes.

To scale: if its ID gene were 1 cm long, its genome would stretch 14 meters. Yours would stretch 21 kilometers. One reference genome; strains vary. NCBI GCF_000010425.1

Lab traits Gram +Rod-shapedNon-motileAnaerobe
Also known as Bifidobacterium faecaleBifidobacterium stercoris
Capabilities, not measurements of anyone's gut

What it can do

Makes
  • Can make lactic acid What yogurt bacteria make; other microbes turn it into butyrate.
Eats
  • Can ferment fiber Breaks down dietary fiber that our own enzymes can't.
  • Can eat inulin A fiber in onions, garlic, leeks, chicory and bananas (also sold as FOS).
  • Can eat resistant starch Starch that reaches the colon: cooled potatoes and rice, green bananas, beans.
  • Can use lactose The sugar in milk and dairy.
Changes
  • Can change bile acids Modifies the bile acids the liver makes to digest fat.

Not seen in its genomes: make butyrate, make propionate, eat pectin, feed on gut mucus, make hydrogen sulfide, make methane.

All 13 capabilities and their evidence
CapabilityVerdict Genome analysis Lab tests Published research
Can make butyrateNot seen0 of 15 genomes—No papers
Can make propionateNot seen0 of 15 genomes—No papers
Can make lactic acidCan15 of 15 genomes—Papers say yes
Can ferment fiberCan15 of 15 genomes10 of 10 strains · strip test Papers say yes
Can eat inulinCan13 of 15 genomes1 of 5 strains · strip test Strip tests often miss fiber-eaters, so this doesn't override the genomes.Papers say yes
Can eat resistant starchCan13 of 15 genomes—No papers
Can eat pectinNot seen0 of 15 genomes—No papers
Can use lactoseCan15 of 15 genomes9 of 10 strains No papers
Can feed on gut mucusNot seen0 of 15 genomes—No papers
Can change bile acidsCan1 of 15 genomes—Papers say yes
Can make B vitaminsCan15 of 15 genomes—Papers say yes
Can make hydrogen sulfideNot seen0 of 15 genomes—No papers
Can make methaneNot seen0 of 15 genomes—No papers

AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0

What’s typical · a description, not a comparison

In healthy guts

Everyone · 12,213 people · 129 studies
How common

Found in 53% of healthy people.

How big a slice of the gut
  1. largest Segatella copri 6.2%
  2. 2nd largest Phocaeicola vulgatus 5.0%
  3. 3rd largest Faecalibacterium prausnitzii 4.7%
  4. 4th largest Bacteroides uniformis 3.2%
  5. 5th largest Agathobacter rectalis 2.5%
  6. 6th largest Alistipes putredinis 2.3%
  7. 7th largest Bifidobacterium longum 2.1%
  8. 8th largest Ruminococcus bromii 1.8%
  9. top 20 Bifidobacterium adolescentis 1.6%
  10. 2,169 other microbes, each a sliver 55.0%
  11. 15.6%

On average, 1.6% of the microbes in a healthy gut: among the 20 largest slices.

By age and sex

Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.

By age
367 people · 12% carry it 1.1% of the microbes top 20
198 people · 5 studies 49% carry it 0.5% of the microbes top 40
57 people · 51% carry it 0.5% of the microbes top 30
1,283 people · 27 studies 46% carry it 0.7% of the microbes top 30
142 people · 15 studies 21% carry it 0.2% of the microbes top 80
By sex
2,063 people · 48% carry it 0.8% of the microbes top 30
1,530 people · 29 studies 49% carry it 0.9% of the microbes top 20

Where these numbers come from

Who
12,213 healthy people from 129 studies in GMrepo, by its own “Health” label. Whole-genome sequencing only; one sample is one person.
How common
The share of them whose sample has any of it.
Slice
Its average share of the microbes in a healthy gut, across everyone, carriers or not. The slices add up to 84.4%: the rest is reads GMrepo couldn’t place at this rank, shown as “Not identified to a species”.
Age and sex
From the samples that record them (about 17% record an age and 29% a sex). A group with fewer than 50 people isn’t shown.
Ranks
A slice’s rank is a place among the 2,178 microbes we have numbers for, within the group shown: exact in the top 10, then rounded bands.
Analysis
Ours, of GMrepo’s per-sample data. GMrepo on Data sources
The 129 studies behind these numbers

Largest first by people. Each is a GMrepo project.

StudyPeopleWith ageWith sex
A study in the United States PRJNA695570 ↗ 1,767 0 1,759
A study in Japan PRJNA1077400 ↗ 1,268 0 0
A study in Spain PRJEB61680 ↗ 839 0 0
Zhong et al. 2019 · the Netherlands PRJEB26795 ↗ 572 0 0
A study in the Netherlands PRJNA942468 ↗ 517 0 0
Shang et al. 2021 · Australia PRJNA492716 ↗ 370 0 84
A study in the United States PRJNA398089 ↗ 363 237 363
A study in the United States PRJNA795985 ↗ 290 0 0
Zhang et al. 2022 · China PRJNA801051 ↗ 239 0 0
A study in Ireland PRJEB46398 ↗ 237 0 0
Valles-Colomer et al. 2023 · Italy PRJEB63351 ↗ 225 0 0
A study in the United States PRJNA633576 ↗ 225 223 0
Lee et al. 2024 · the United Kingdom PRJEB52380 ↗ 177 0 0
A study in the United States PRJEB37924 ↗ 164 0 0
A study in China PRJNA542578 ↗ 151 0 0
A study in the United States PRJNA993675 ↗ 142 142 142
Lee et al. 2022 · South Korea PRJEB45443 ↗ 112 0 0
A study in China PRJEB65297 ↗ 111 0 0
A study in India PRJNA397112 ↗ 110 110 0
A study in Japan PRJDB13214 ↗ 105 0 0
A study in China PRJNA686835 ↗ 104 0 0
A study in China PRJNA763023 ↗ 100 0 0
A study in China PRJNA994318 ↗ 100 0 0
A study in the United States PRJEB28543 ↗ 96 96 96
A study in Italy PRJNA716780 ↗ 94 94 94
A study in China PRJNA509999 ↗ 93 0 0
A study in the United States PRJNA878603 ↗ 92 92 92
Guo et al. 2023 · the United States PRJNA751448 ↗ 91 91 91
A study in China PRJNA793776 ↗ 89 89 89
A study in China PRJNA888860 ↗ 88 0 0
A study in Ireland PRJEB15388 ↗ 85 0 0
A study in China PRJNA731589 ↗ 85 85 0
A study in Israel PRJNA994433 ↗ 80 80 0
A study in Canada PRJNA521587 ↗ 79 78 79
La Reau et al. 2023 · the United States PRJNA917645 ↗ 76 0 0
Pomyen et al. 2023 · Thailand PRJNA932948 ↗ 76 0 76
A study in the United States PRJEB53403 ↗ 75 45 45
Eriksen et al. 2023 · Sweden PRJNA633381 ↗ 74 0 0
A study in China PRJNA356102 ↗ 72 0 0
A study in China PRJNA689961 ↗ 70 0 0
A study in China PRJNA449784 ↗ 69 0 0
Duru et al. 2024 · Finland PRJEB59350 ↗ 66 0 0
Roth-Schulze et al. 2021 · Australia PRJNA604850 ↗ 66 66 48
Wan et al. 2024 · China PRJNA1037036 ↗ 64 64 64
A study in China PRJNA686821 ↗ 64 0 0
Fulcher et al. 2022 · the United States PRJNA836336 ↗ 64 0 0
Hu et al. 2023 · China PRJNA893406 ↗ 64 0 0
A study in Italy PRJNA553191 ↗ 62 0 0
Wilson et al. 2024 · the United States PRJEB59709 ↗ 59 0 0
A study in the United States PRJNA822660 ↗ 58 58 58
A study in the United States PRJNA314903 ↗ 50 0 0
A study in the United States PRJNA379741 ↗ 50 0 50
A study in China PRJNA674716 ↗ 50 0 0
A study in China PRJNA762484 ↗ 49 20 21
Yan et al. 2023 · China PRJNA808806 ↗ 48 0 0
Stockdale et al. 2022 · Ireland PRJNA813736 ↗ 48 40 41
Tao et al. 2025 · China PRJNA1135717 ↗ 47 0 0
A study in the United States PRJNA660443 ↗ 44 0 0
A study in China PRJNA946183 ↗ 44 0 0
A study in China PRJNA530971 ↗ 43 0 0
Ye et al. 2023 · China PRJNA853814 ↗ 42 42 0
A study in China PRJNA943232 ↗ 42 42 42
A study in the United Kingdom PRJEB17978 ↗ 41 0 0
A study in China PRJNA588035 ↗ 39 0 0
A study in China PRJNA349463 ↗ 33 0 0
A study in India PRJNA531203 ↗ 31 0 0
A study in Switzerland PRJEB24557 ↗ 30 0 0
A study in India PRJNA792685 ↗ 30 0 0
A study in China PRJNA808649 ↗ 30 30 30
Pötgens et al. 2024 · Belgium PRJNA813705 ↗ 30 0 0
Grion et al. 2024 · Spain PRJNA961076 ↗ 30 0 0
A study in Canada PRJEB21933 ↗ 29 0 0
A study PRJEB32767 ↗ 29 0 0
A study in the United States PRJEB53401 ↗ 29 29 29
A study in Poland PRJNA1125836 ↗ 28 28 28
Chen et al. 2023 · China PRJEB55711 ↗ 27 0 0
A study in the United States PRJNA629755 ↗ 27 0 0
A study in China PRJNA818062 ↗ 27 0 0
Wang et al. 2023 · China PRJNA905444 ↗ 27 0 0
A study in Spain PRJEB62571 ↗ 26 0 0
A study in China PRJNA769284 ↗ 26 0 0
Lv et al. 2024 · China PRJEB52189 ↗ 25 0 0
Xiao et al. 2024 · China PRJNA938297 ↗ 25 25 25
A study in Germany PRJEB76677 ↗ 24 0 0
Elie et al. 2023 · France PRJNA648321 ↗ 24 0 0
A study in Mali PRJNA936589 ↗ 24 0 0
A study in the United States PRJNA1044118 ↗ 23 0 0
A study in Turkey PRJNA1167935 ↗ 23 0 0
A study in Russia PRJNA762199 ↗ 23 23 23
Ievina et al. 2024 · Latvia PRJEB80379 ↗ 22 0 0
A study in China PRJNA896336 ↗ 22 0 0
A study in China PRJNA688881 ↗ 21 0 0
Edwinson et al. 2022 · the United States PRJNA705217 ↗ 21 21 21
A study in France PRJEB55534 ↗ 20 0 0
A study in Canada PRJNA1022308 ↗ 20 0 0
A study in China PRJNA1138893 ↗ 20 0 0
Schaefer et al. 2022 · the United States PRJNA800662 ↗ 20 0 0
Ding et al. 2023 · China PRJNA999028 ↗ 20 0 0
A study in the United States PRJEB42155 ↗ 18 0 0
A study in Japan PRJNA665854 ↗ 18 0 0
A study in Canada PRJNA742740 ↗ 17 0 0
Stockdale et al. 2022 · the United States PRJNA626004 ↗ 16 0 0
A study in China PRJNA858062 ↗ 16 16 16
A study in China PRJNA429990 ↗ 15 0 0
Wan et al. 2019 · China PRJNA532538 ↗ 15 0 0
A study in China PRJNA624223 ↗ 15 15 15
A study in the United States PRJNA634145 ↗ 15 15 15
A study in China PRJNA734379 ↗ 15 0 15
Sadeghi et al. 2024 · France PRJEB70916 ↗ 14 14 14
A study in Singapore PRJNA272371 ↗ 14 14 14
A study in India PRJNA983946 ↗ 14 14 14
A study in Sweden PRJEB38997 ↗ 13 0 0
Seishima et al. 2019 · Japan PRJNA511372 ↗ 13 0 0
A study in China PRJEB54728 ↗ 12 0 0
A study in Switzerland PRJEB13835 ↗ 11 0 0
A study in Japan PRJNA846495 ↗ 11 0 0
Joensen et al. 2017 · Denmark PRJEB14038 ↗ 10 0 0
A study in the United Kingdom PRJEB53891 ↗ 10 0 0
A study in Iran PRJNA1050885 ↗ 10 0 0
A study in China PRJNA730640 ↗ 10 0 0
A study in Israel PRJNA939026 ↗ 10 9 0
Ye et al. 2023 · China PRJNA993632 ↗ 10 0 0
A study in China PRJNA1024678 ↗ 9 0 0
Wang et al. 2024 · Switzerland PRJNA363003 ↗ 9 0 0
A study in the United States PRJNA613834 ↗ 9 0 0
A study in the United States PRJNA896226 ↗ 8 0 0
A study in Spain PRJNA1029046 ↗ 7 0 0
A study in China PRJNA492189 ↗ 5 0 0
A study in France PRJNA287878 ↗ 2 0 0
Compared within studies that had both

In conditions

Compared with healthy people in the same studies, it’s less common in 10 conditions and more common in none. Only studies that had both are counted.

A difference is an association: it doesn’t mean this microbe causes, prevents or treats any of these.

Strongest first, then the biggest gap · Each figure is 10 people
  1. Crohn's disease 1,313 people · 8 studies Less common in people with it Healthy 43% With it 20%
  2. COVID-19 259 people · 3 studies Less common in people with it Healthy 67% With it 45%
  3. Chronic fatigue syndrome 302 people · 3 studies Less common in people with it Healthy 35% With it 21%
  4. Ulcerative colitis 820 people · 7 studies Less common in people with it Healthy 47% With it 35%
  5. Irritable bowel syndrome 372 people · 2 studies Less common in people with it Healthy 52% With it 29%
  6. Multiple sclerosis 113 people · 2 studies Less common in people with it Healthy 57% With it 33%
  7. Chronic kidney failure 347 people · 2 studies Less common in people with it Healthy 37% With it 24%
  8. Diarrhea 65 people · 1 study Less common in people with it Healthy 90% With it 4.6%
  9. High blood pressure 50 people · 1 study Less common in people with it Healthy 52% With it 12%
  10. Cavernous hemangioma 127 people · 1 study Less common in people with it Healthy 59% With it 29%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules
Fig. 1 · By how people live

In studies of how people live

All factors →

“Higher” is the study’s measure: on average, a bigger share of gut bacteria across everyone in the group, carriers or not. It isn’t how many people carry it. An association the authors report, measured once per person. It doesn’t mean a diet changes this microbe, or that the microbe affects health.

PubMed · human studies and reviews first

Recent research

All research on it
  1. PubMed ↗
  2. PubMed ↗
  3. PubMed ↗
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  5. PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 400 linked papers, last 10 years

In people · from PubMed and product labels

Strains studied

How much each strain has been studied in people, not whether it works. Many trials test a strain inside a blend, so those are counted apart, and reviews are summaries of trials, so they're never counted as more trials.

  1. B. adolescentis Bac30

    In 1 product →

    No human trials found yet

Human trials, meta-analyses and systematic reviews naming the strain · animal and lab studies not counted · Data sources

On the shelf

Products that contain it