Oscillibacter valericigenes
What's this?
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Its ID gene: the stretch scientists read to tell microbes apart. Each bar is one letter of its DNA. Every species has its own order of letters, so the pattern works like a fingerprint. Close relatives share most of it.
16S rRNA gene, V4 region: the 253 letters between the standard primers (515F/806R), which are the same in every species. One reference sequence; strains can differ by a letter or two. NCBI NR_074793.2
Small for a gut microbe: longer than 27% of the 2,354 we have genomes for.
59% G+C, higher than 72% of gut microbes.
To scale: if its ID gene were 1 cm long, its genome would stretch 17 meters. Yours would stretch 21 kilometers. One reference genome; strains vary. NCBI GCF_021531915.1
What it can do
- Can make butyrate A short-chain fatty acid that feeds the cells lining the colon.
Not seen in its published research: use lactose.
All 13 capabilities and their evidence
| Capability | Verdict | Genome analysis | Lab tests | Published research |
|---|---|---|---|---|
| Can make butyrate | Can | — | — | Papers say yes |
| Can use lactose | Not seen | — | — | Papers say no |
| Can make propionate | Not checked | — | — | No papers |
| Can make lactic acid | Not checked | — | — | No papers |
| Can ferment fiber | Not checked | — | — | No papers |
| Can eat inulin | Not checked | — | — | No papers |
| Can eat resistant starch | Not checked | — | — | No papers |
| Can eat pectin | Not checked | — | — | No papers |
| Can feed on gut mucus | Not checked | — | — | No papers |
| Can change bile acids | Not checked | — | — | No papers |
| Can make B vitamins | Not checked | — | — | No papers |
| Can make hydrogen sulfide | Not checked | — | — | No papers |
| Can make methane | Not checked | — | — | No papers |
AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0
In healthy guts
Found in 70% of healthy people.
- largest Segatella copri 6.2%
- 2nd largest Phocaeicola vulgatus 5.0%
- 3rd largest Faecalibacterium prausnitzii 4.7%
- 4th largest Bacteroides uniformis 3.2%
- 5th largest Agathobacter rectalis 2.5%
- 6th largest Alistipes putredinis 2.3%
- 7th largest Bifidobacterium longum 2.1%
- 8th largest Ruminococcus bromii 1.8%
- top 60 Oscillibacter valericigenes 0.3%
- 2,169 other microbes, each a sliver 56.4%
- 15.6%
On average, 0.3% of the microbes in a healthy gut: among the 60 largest slices.
Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.
In conditions
Compared with healthy people in the same studies, it’s less common in 8 conditions and more common in none. Only studies that had both are counted.
A difference is an association: it doesn’t mean this microbe causes, prevents or treats any of these.
Strongest first, then the biggest gap · Each figure is 10 people- Chronic fatigue syndrome As many carry it in people with it Healthy 93% With it 88%
Carriers have less, in 3 of 3 studies (0.37% → 0.23% of their gut microbes).
Recent research
Source: PubMed, U.S. National Library of Medicine · 13 linked papers, last 10 years