Prevotella bivia
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Its ID gene: the stretch scientists read to tell microbes apart. Each bar is one letter of its DNA. Every species has its own order of letters, so the pattern works like a fingerprint. Close relatives share most of it.
16S rRNA gene, V4 region: the 253 letters between the standard primers (515F/806R), which are the same in every species. One reference sequence; strains can differ by a letter or two. NCBI NR_113096.1
Formerly Bacteroides bivius.
Small for a gut microbe: longer than 29% of the 2,354 we have genomes for.
40% G+C, higher than 27% of gut microbes.
To scale: if its ID gene were 1 cm long, its genome would stretch 17 meters. Yours would stretch 21 kilometers. One reference genome; strains vary. NCBI GCF_000262545.1
What it can do
- Can ferment fiber Breaks down dietary fiber that our own enzymes can't. 2 of 11 strains can
- Can use lactose The sugar in milk and dairy.
Not seen in its genomes: make butyrate, make propionate, make lactic acid, eat inulin, eat resistant starch, eat pectin, feed on gut mucus, change bile acids, make B vitamins, make hydrogen sulfide, make methane.
All 13 capabilities and their evidence
| Capability | Verdict | Genome analysis | Lab tests | Published research |
|---|---|---|---|---|
| Can make butyrate | Not seen | 0 of 2 genomes | — | No papers |
| Can make propionate | Not seen | 0 of 2 genomes | — | No papers |
| Can make lactic acid | Not seen | 0 of 2 genomes | — | No papers |
| Can ferment fiber | Some strains | 0 of 2 genomes | 2 of 11 strains · strip test | No papers |
| Can eat inulin | Not seen | 0 of 2 genomes | — | No papers |
| Can eat resistant starch | Not seen | 0 of 2 genomes | — | No papers |
| Can eat pectin | Not seen | 0 of 2 genomes | — | No papers |
| Can use lactose | Can | 2 of 2 genomes | — | No papers |
| Can feed on gut mucus | Not seen | 0 of 2 genomes | — | No papers |
| Can change bile acids | Not seen | 0 of 2 genomes | — | No papers |
| Can make B vitamins | Not seen | 0 of 2 genomes | — | No papers |
| Can make hydrogen sulfide | Not seen | 0 of 2 genomes | — | No papers |
| Can make methane | Not seen | 0 of 2 genomes | — | No papers |
AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0
In healthy guts
Found in 3.4% of healthy people.
- largest Segatella copri 6.2%
- 2nd largest Phocaeicola vulgatus 5.0%
- 3rd largest Faecalibacterium prausnitzii 4.7%
- 4th largest Bacteroides uniformis 3.2%
- 5th largest Agathobacter rectalis 2.5%
- 6th largest Alistipes putredinis 2.3%
- 7th largest Bifidobacterium longum 2.1%
- 8th largest Ruminococcus bromii 1.8%
- top 20% Prevotella bivia 0.01%
- 2,169 other microbes, each a sliver 56.7%
- 15.6%
On average, 0.01% of the microbes in a healthy gut: larger than 80% of species’ slices.
Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.
In conditions
Compared with healthy people in the same studies, it’s less common in none and more common in none. Only studies that had both are counted.
A difference is an association: it doesn’t mean this microbe causes, prevents or treats any of these.