Candidatus Borkfalkia ceftriaxoniphila
No reference ID-gene sequence in NCBI yet Data sources
Small for a gut microbe: longer than 33% of the 2,354 we have genomes for.
52% G+C, higher than 58% of gut microbes.
To scale: if its ID gene were 1 cm long, its genome would stretch 17 meters. Yours would stretch 21 kilometers. One reference genome; strains vary. NCBI GCF_004134775.1
What it can do
- Can make propionate A short-chain fatty acid, mostly used by the liver.
- Can make lactic acid What yogurt bacteria make; other microbes turn it into butyrate.
- Can ferment fiber Breaks down dietary fiber that our own enzymes can't.
Not seen in its genomes: make butyrate, eat inulin, eat resistant starch, eat pectin, use lactose, feed on gut mucus, change bile acids, make B vitamins, make hydrogen sulfide, make methane.
All 13 capabilities and their evidence
| Capability | Verdict | Genome analysis | Lab tests | Published research |
|---|---|---|---|---|
| Can make butyrate | Not seen | 0 of 1 genome | — | No papers |
| Can make propionate | Can | 1 of 1 genome | — | No papers |
| Can make lactic acid | Can | 1 of 1 genome | — | No papers |
| Can ferment fiber | Can | 1 of 1 genome | — | No papers |
| Can eat inulin | Not seen | 0 of 1 genome | — | No papers |
| Can eat resistant starch | Not seen | 0 of 1 genome | — | No papers |
| Can eat pectin | Not seen | 0 of 1 genome | — | No papers |
| Can use lactose | Not seen | 0 of 1 genome | — | No papers |
| Can feed on gut mucus | Not seen | 0 of 1 genome | — | No papers |
| Can change bile acids | Not seen | 0 of 1 genome | — | No papers |
| Can make B vitamins | Not seen | 0 of 1 genome | — | No papers |
| Can make hydrogen sulfide | Not seen | 0 of 1 genome | — | No papers |
| Can make methane | Not seen | 0 of 1 genome | — | No papers |
AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0
In healthy guts
Found in 13% of healthy people.
- largest Segatella copri 6.2%
- 2nd largest Phocaeicola vulgatus 5.0%
- 3rd largest Faecalibacterium prausnitzii 4.7%
- 4th largest Bacteroides uniformis 3.2%
- 5th largest Agathobacter rectalis 2.5%
- 6th largest Alistipes putredinis 2.3%
- 7th largest Bifidobacterium longum 2.1%
- 8th largest Ruminococcus bromii 1.8%
- top 15% Candidatus Borkfalkia ceftriaxoniphila 0.01%
- 2,169 other microbes, each a sliver 56.7%
- 15.6%
On average, 0.01% of the microbes in a healthy gut: larger than 85% of species’ slices.
Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.
In conditions
Compared with healthy people in the same studies, it’s less common in 4 conditions and more common in 2 conditions. Only studies that had both are counted.
A difference is an association: it doesn’t mean this microbe causes, prevents or treats any of these.
Strongest first, then the biggest gap · Each figure is 10 peopleIn studies of how people live
“Higher” is the study’s measure: on average, a bigger share of gut bacteria across everyone in the group, carriers or not. It isn’t how many people carry it. An association the authors report, measured once per person. It doesn’t mean a diet changes this microbe, or that the microbe affects health.