Randomized trial Nutrients · 2026 Sourdough Bread and Baker's Yeast Bread Affect Gut Symptoms and Targeted Gut Microbial Taxa Differently: A Randomised Controlled Trial. Watters SIN, Henriksen C, Gjøvik M, et al. Alistipes putredinisAlistipes shahiiBifidobacterium adolescentisBifidobacterium longum PubMed ↗
Randomized trial Journal of gastroenterology and hepatology · 2026 Consolidation Therapy of Probiotics With Rifaximin Prevent Relapse in Rifaximin-Responsive Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Randomized Clinical Trial. Zhong J, Xu Z, Chen W, et al. Enterococcus faecium PubMed ↗
Observational BMC microbiology · 2026 Metagenomic profiling of gut microbiome in post-cholecystectomy patients with diarrhea: a nested case-control study. Ye J, Mao P, Li B, et al. Bacteroides intestinalisCoprococcus comesSegatella copri PubMed ↗
Randomized trial International microbiology · 2026 Bifidobacterium breve PRL2020 mitigates antibiotic-induced gut symptoms and dysbiosis in children treated with amoxicillin or amoxicillin-clavulanate. Di Pierro F, Carugno A, Baggi E, et al. Bifidobacterium breve PubMed ↗
Randomized trial Diabetes, obesity & metabolism · 2026 Bifidobacterium bifidum G9-1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open-Label, Randomized Controlled Trial (Binary STAR Study). Kobayashi G, Hashimoto Y, Matsuyama T, et al. Bifidobacterium bifidum PubMed ↗
Review Archives of microbiology · 2026 Divergent mechanistic pathways of diarrheagenic bacterial infections at the host-microbiota interface: a review. Bayode MT, Olawale OE, Olusola-Makinde OO Escherichia coli PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Comparative metagenomic analysis of diarrheal and non-diarrheal gut microbiome delineating the identification of prospective prognostic markers and probiotics to protect from diarrhea: a brief report. De R, Kanungo S, Mukhopadhyay AK, et al. Segatella copri PubMed ↗
Randomized trial Scientific reports · 2026 Probiotic intervention not beneficial to prevent antibiotic-associated diarrhea in absence of antibiotic-induced microbiome disruption. Merenstein D, Grant-Beurmann S, Sanders ME, et al. Bifidobacterium animalis PubMed ↗
Review Terapevticheskii arkhiv · 2026 [Probiotics' position in clinical practice: focus on the combination of Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12). A review]. Gorelov AV, Kozlov RS, Andreeva IV, et al. Bifidobacterium animalis PubMed ↗
Review International journal of molecular sciences · 2026 Enteric Infections, Dysbiosis, and Metabolic Dysfunction: The Role of Diarrheagenic Pathogens in Insulin Resistance. Zermeño-Ruiz M, Gutierrez-Gutierrez F, Anaya-Ambriz EJ, et al. Escherichia coli PubMed ↗
Randomized trial Nature communications · 2025 Gut Prevotella stercorea associates with protection against infection in rural African children. Ofordile O, Pereira DIA, Prentice AM, et al. Escherichia coli PubMed ↗
Review Current opinion in clinical nutrition and metabolic care · 2025 An update on probiotics in paediatrics. Zemła M, Kotowska-Bąbol M, Szajewska H Bifidobacterium animalisStreptococcus thermophilus PubMed ↗
Randomized trial Arquivos de gastroenterologia · 2025 EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS. DE Souza GC, Araujo Filho HB, DE Oliveira CZ, et al. Bifidobacterium animalisBifidobacterium bifidum PubMed ↗
Randomized trial The American journal of gastroenterology · 2025 Efficacy and Safety of Gelatin Tannate and Tyndallized Acid Lactic Bacteria in Adults With Chronic Diarrhea and Altered Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled Study. Santos J, Iordache A, Manolache M Akkermansia muciniphilaFaecalibacterium prausnitzii PubMed ↗
Meta-analysis The Tohoku journal of experimental medicine · 2025 Live Combined Bacillus Subtilis and Enterococcus Faecium for the Treatment and Prevention of Antibiotic-Associated Diarrhea: A RCT-Based Meta-Analysis. Zhang N, Chen Y, Shen Z Enterococcus faecium PubMed ↗
Randomized trial Scientific reports · 2025 Impact of Enterococcus faecium 129 BIO 3B-R on Helicobacter pylori eradication therapy side effects in adult patients: a randomized, double-blind, placebo-controlled study. Tokunaga E, Inoue J, Asaji N, et al. Enterococcus faecium PubMed ↗
Observational European journal of pediatrics · 2025 Fecal gut microbiome alterations and its association with lactose intolerance in children with rotavirus infection-related diarrhea. Ye Q, Zhang Z, Chen T, et al. Mediterraneibacter gnavus PubMed ↗
Review The Journal of nutrition · 2025 The Potential and Underlying Mechanisms of Punicalagin in Mitigating Enterotoxigenic Escherichia coli-Induced Diarrhea. Li XG, Zhao X, Zheng J, et al. Escherichia coli PubMed ↗
Observational Inflammatory bowel diseases · 2025 The Fecal Microbiome of IBD Patients Is Less Divertible by Bowel Preparation Compared to Healthy Controls: Results From a Prospective Study. Blesl A, Binder L, Halwachs B, et al. Anaerobutyricum hallii PubMed ↗
Randomized trial Phytomedicine · 2025 Butyrate-producing commensal bacteria mediates the efficacy of herbal medicine JCM-16021 on abdominal pain in diarrhea-predominant irritable bowel syndrome: a randomized clinical trial. Zhai L, Zheng Y, Lo CW, et al. Agathobacter rectalis PubMed ↗
Observational Nature communications · 2025 Association of distinct microbial and metabolic signatures with microscopic colitis. Chen AS, Kim H, Nzabarushimana E, et al. Bacteroides stercorisBlautia gluceraseaHaemophilus parainfluenzaeVeillonella dispar PubMed ↗
Review Nutrients · 2025 Undernutrition and Intestinal Infections in Children: A Narrative Review. Carvalho MCDC, Ribeiro SA, de Sousa LS, et al. Escherichia coli PubMed ↗
Observational Nature communications · 2024 Gut microbiota patterns associated with duration of diarrhea in children under five years of age in Ethiopia. Tesfaw G, Siraj DS, Abdissa A, et al. Faecalibacterium prausnitziiSegatella copri PubMed ↗
Randomized trial Gut microbes · 2024 Effects of postbiotics on chronic diarrhea in young adults: a randomized, double-blind, placebo-controlled crossover trial assessing clinical symptoms, gut microbiota, and metabolite profiles. Guo S, Ma T, Kwok LY, et al. Dysosmobacter welbionisFaecalibacterium prausnitzii PubMed ↗
Randomized trial Nutrients · 2024 Effectiveness of Psychobiotic Bifidobacterium breve BB05 in Managing Psychosomatic Diarrhea in College Students by Regulating Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled Trial. Wang Y, Wang Y, Ding K, et al. Bifidobacterium breve PubMed ↗
Randomized trial Gut microbes · 2024 A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Srivastava S, Basak U, Naghibi M, et al. Bifidobacterium longum PubMed ↗
Randomized trial European journal of clinical nutrition · 2024 Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study. Chen K, Jin S, Ma Y, et al. Bifidobacterium animalisBifidobacterium breveCollinsella aerofaciens PubMed ↗
Review Frontiers in cellular and infection microbiology · 2024 Fine-tuning of post-weaning pig microbiome structure and functionality by in-feed zinc oxide and antibiotics use. Ortiz Sanjuán JM, Manzanilla EG, Cabrera-Rubio R, et al. Escherichia coli PubMed ↗
Randomized trial Gut microbes · 2024 Collinsella aerofaciens as a predictive marker of response to probiotic treatment in non-constipated irritable bowel syndrome. Gargari G, Mantegazza G, Cremon C, et al. Collinsella aerofaciens PubMed ↗
Observational Gut microbes · 2023 Why are so many enteric pathogen infections asymptomatic? Pathogen and gut microbiome characteristics associated with diarrhea symptoms and carriage of diarrheagenic E. coli in northern Ecuador. Jesser KJ, Trueba G, Konstantinidis KT, et al. Escherichia coli PubMed ↗
Meta-analysis Journal of infection and chemotherapy · 2023 Effects of probiotics in children with acute gastroenteritis: A systematic review and meta-analysis focusing on probiotics utilized in Japan. Higuchi T, Furuichi M, Maeda N, et al. Enterococcus faecium PubMed ↗
Randomized trial Journal of medical microbiology · 2023 Gut microbiota associated with the mitigation effect of synbiotics on adverse events of neoadjuvant chemotherapy in patients with esophageal cancer: A retrospective exploratory study. Sugimoto T, Atobe S, Kado Y, et al. Anaerostipes hadrusBifidobacterium breveBifidobacterium pseudocatenulatum PubMed ↗
Review Drugs · 2023 Antibiotics and Probiotics for Irritable Bowel Syndrome. Goodoory VC, Ford AC Bifidobacterium bifidum PubMed ↗
Randomized trial Nutrition · 2023 Adjunctive efficacy of Lactis XLTG11 for Acute diarrhea in children: A randomized, blinded, placebo-controlled study. Chen K, Jin S, Ma Y, et al. Bifidobacterium animalis PubMed ↗
Randomized trial Internal medicine · 2023 Efficacy and Safety of Synbiotics in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation: A Randomized, Double-blinded, Placebo-controlled Pilot Study. Mizutani Y, Kawamoto S, Takahashi M, et al. Bifidobacterium longum PubMed ↗
Randomized trial Food & function · 2023 Cinnamon (Cinnamomum cassia) water extract improves diarrhea symptoms by changing the gut environment: a randomized controlled trial. Park SY, Kim YD, Kim MS, et al. Bifidobacterium longum PubMed ↗
Randomized trial Digestive diseases · 2023 Impact of Saccharomyces boulardii CNCM I-745 on Bacterial Overgrowth and Composition of Intestinal Microbiota in Diarrhea-Predominant Irritable Bowel Syndrome Patients: Results of a Randomized Pilot Study. Bustos Fernández LM, Man F, Lasa JS Faecalibacterium prausnitzii PubMed ↗
Randomized trial JPMA. The Journal of the Pakistan Medical Association · 2022 Evaluation of treatment in acute gastroenteritis: A comparative study. Yalcin G, Demirbas F, Bacalan F, et al. Bifidobacterium bifidumBifidobacterium breveBifidobacterium longum PubMed ↗
Randomized trial JAMA pediatrics · 2022 Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial. Lukasik J, Dierikx T, Besseling-van der Vaart I, et al. Bifidobacterium animalisBifidobacterium bifidumLigilactobacillus salivarius PubMed ↗
Meta-analysis Frontiers in cellular and infection microbiology · 2022 Efficacy and safety of herbal formulas with the function of gut microbiota regulation for gastric and colorectal cancer: A systematic review and meta-analysis. Xu B, Wang X, Wang H, et al. Enterococcus faecalis PubMed ↗
Review Food & function · 2022 Probiotic Escherichia coli NISSLE 1917 for inflammatory bowel disease applications. Zhao Z, Xu S, Zhang W, et al. Escherichia coli PubMed ↗
Observational The American journal of clinical nutrition · 2022 Full breastfeeding protection against common enteric bacteria and viruses: results from the MAL-ED cohort study. McCormick BJJ, Richard SA, Murray-Kolb LE, et al. Escherichia coli PubMed ↗
Randomized trial Probiotics and antimicrobial proteins · 2022 Bifidobacterium lactis CCT 7858 Improves Gastrointestinal Symptoms by Antibiotics Treatment: a Double-Blind, Randomized, Placebo-Controlled Trial. Michels M, Córneo E, Cucker L, et al. Bifidobacterium animalis PubMed ↗
Observational BMC microbiology · 2021 Involvement of mucosal flora and enterochromaffin cells of the caecum and descending colon in diarrhoea-predominant irritable bowel syndrome. Yang J, Wang P, Liu T, et al. [Ruminococcus] torques PubMed ↗
Randomized trial Frontiers in immunology · 2021 Lactobacillus plantarum CCFM1143 Alleviates Chronic Diarrhea via Inflammation Regulation and Gut Microbiota Modulation: A Double-Blind, Randomized, Placebo-Controlled Study. Yang B, Yue Y, Chen Y, et al. Escherichia coli PubMed ↗
Randomized trial Probiotics and antimicrobial proteins · 2021 Efficacy of a Probiotic Consisting of Lacticaseibacillus rhamnosus PDV 1705, Bifidobacterium bifidum PDV 0903, Bifidobacterium longum subsp. infantis PDV 1911, and Bifidobacterium longum subsp. longum PDV 2301 in the Treatment of Hospitalized Patients with COVID-19: a Randomized Controlled Trial. Ivashkin V, Fomin V, Moiseev S, et al. Bifidobacterium bifidumBifidobacterium longum PubMed ↗
Review Minerva gastroenterology · 2021 Microbiota and the irritable bowel syndrome. Sabo CM, Dumitrascu DL Escherichia coli PubMed ↗
Randomized trial Nutrients · 2021 Bifidobacterium animalis subsp. lactis BB-12 Protects against Antibiotic-Induced Functional and Compositional Changes in Human Fecal Microbiome. Merenstein D, Fraser CM, Roberts RF, et al. Bifidobacterium animalis PubMed ↗
Randomized trial Clinical gastroenterology and hepatology · 2021 A Nonviable Probiotic in Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. Mack I, Schwille-Kiuntke J, Mazurak N, et al. Enterococcus faecalis PubMed ↗
Randomized trial Nutrients · 2021 The Effectiveness and Safety of Multi-Strain Probiotic Preparation in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Controlled Study. Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, et al. Streptococcus thermophilus PubMed ↗