Plate · Actinomycetota

Rothia

Formerly Stomatococcus.

Species10named in this genus

Products0across its species

Samples10,501healthy and not

Also known as Stomatococcus

The genus

Species in this genus

Include unnamed strains (1)

Species	Healthy guts ↓ 0–100%	Products
Rothia mucilaginosa	18%	0
Rothia aeria	<1%	0
Rothia kristinae	<1%	0
Rothia koreensis	<1%	0
Rothia terrae	<1%	0
Rothia endophytica	<1%	0
Rothia aerolata	0%	0
Rothia amarae	0%	0
Rothia halotolerans	0%	0
Rothia nasimurium	0%	0
Across the genus	18%	0

* Counted in the same healthy people as the species (whole-genome samples). All bars use the same 0–100% scale. A product with two Rothia species counts once in the genus total.

What they are

Its species' DNA

A C G T

Genome sizes · 10 Rothia species

Shortest we have Mycoplasmoides genitalium 0.6M

⋮ 483 shorter than any Rothia

Rothia mucilaginosa 2.3M

Rothia amarae 2.3M

Rothia kristinae 2.4M

Rothia aerolata 2.5M

Rothia nasimurium 2.5M

Rothia endophytica 2.5M

Rothia aeria 2.6M

Rothia terrae 2.7M

Rothia koreensis 2.9M

Rothia halotolerans 3.0M

⋮ 1,258 longer than any Rothia

Longest we have Bradyrhizobium altum 9.8M

Rothia genomes run from 2.3M to 3.0M: small for gut microbes.

One reference genome per species; strains vary.

Their ID genes, lined up: shared stretches form solid stripes

16S gene, V4 region, from one reference sequence per species, aligned so the same positions line up. A blank is a gap: letters other species have and this one lacks. Switch to “Only where they differ” to fade the letters they share.

From its species' genomes and lab tests

What its species can do

A species counts when most of its strains can. Not measured in anyone's gut. 2 of its 10 species aren't in either source yet.

Can make lactic acid 2 of 2 species R. mucilaginosa, R. aeria
Can use lactose 2 of 8 species R. terrae, R. nasimurium
Can make butyrate 0 of 2 species None of its species
Can make propionate 0 of 2 species None of its species
Can ferment fiber 0 of 8 species None of its species
Can eat inulin 0 of 5 species None of its species
Can eat resistant starch 0 of 2 species None of its species
Can eat pectin 0 of 2 species None of its species
Can feed on gut mucus 0 of 2 species None of its species
Can change bile acids 0 of 2 species None of its species
Can make B vitamins 0 of 2 species None of its species
Can make hydrogen sulfide 0 of 2 species None of its species
Can make methane 0 of 2 species None of its species

What’s typical · a description, not a comparison

In healthy guts

Everyone · 12,213 people · 129 studies

How common

Found in 18% of healthy people.

How big a slice of the gut

largest Bacteroides 9.8%
2nd largest Phocaeicola 9.1%
3rd largest Segatella 6.4%
4th largest Bifidobacterium 6.2%
5th largest Faecalibacterium 5.4%
6th largest Alistipes 5.2%
7th largest Blautia 3.6%
8th largest Ruminococcus 3.0%
⋮
Rothia under 0.01%
649 other microbes, each a sliver 32.3%
18.9%

On average, a sliver, under 0.01% of the microbes in a healthy gut.

By age and sex

Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.

By age

367 people · 41% carry it 0.04% of the microbes top 70

198 people · 5 studies 6.1% carry it under 0.01% of the microbes

57 people · 0% carry it 0.00% of the microbes

1,283 people · 27 studies 12% carry it under 0.01% of the microbes

142 people · 15 studies 15% carry it 0.02% of the microbes top 40%

By sex

2,063 people · 4.7% carry it under 0.01% of the microbes

1,530 people · 29 studies 7.3% carry it under 0.01% of the microbes

Compared within studies that had both

In conditions

Compared with healthy people in the same studies, it’s less common in none and more common in 10 conditions. Only studies that had both are counted.

A difference is an association: it doesn’t mean this microbe causes, prevents or treats any of these.

Strongest first, then the biggest gap · Each figure is 10 people

Crohn's disease 1,658 people · 15 studies More common in people with it Healthy 4.9% With it 11%
IgA nephropathy 54 people · 2 studies More common in people with it Healthy 5.2% With it 39%
Immune thrombocytopenia 45 people · 2 studies More common in people with it Healthy 6.5% With it 33%
Liver cirrhosis 45 people · 2 studies More common in people with it Healthy 46% With it 71%
Neuroblastoma 95 people · 2 studies More common in people with it Healthy 14% With it 27%
Mycoplasma pneumonia 81 people · 1 study More common in people with it Healthy 0% With it 36%
Calicivirus infections 31 people · 1 study More common in people with it Healthy 8.0% With it 58%
Blood cancers 29 people · 1 study More common in people with it Healthy 40% With it 83%
Kidney cancer (renal cell carcinoma) 51 people · 1 study More common in people with it Healthy 28% With it 67%
Chronic hepatitis B 58 people · 1 study More common in people with it Healthy 4.3% With it 24%

PubMed · human studies and reviews first

Recent research

No recent human studies or reviews yet. Probiome follows PubMed for the few hundred most-studied microbes; rarer species often only show up in large surveys. Search PubMed for this genus ↗

Rothia

Species in this genus

Its species' DNA

What its species can do

In healthy guts

Where these numbers come from

In conditions

Where these numbers come from

Also compared · 86 conditions

Studies disagree · 1

No meaningful difference · 85

Recent research