Heyndrickxia coagulans
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Its ID gene: the stretch scientists read to tell microbes apart. Each bar is one letter of its DNA. Every species has its own order of letters, so the pattern works like a fingerprint. Close relatives share most of it.
16S rRNA gene, V4 region: the 253 letters between the standard primers (515F/806R), which are the same in every species. One reference sequence; strains can differ by a letter or two. NCBI NR_041523.1
Formerly Bacillus coagulans.
Mid-sized for a gut microbe: longer than 56% of the 2,354 we have genomes for.
47% G+C, higher than 48% of gut microbes.
To scale: if its ID gene were 1 cm long, its genome would stretch 22 meters. Yours would stretch 21 kilometers. One reference genome; strains vary. NCBI GCF_000832905.1
What it can do
- Can ferment fiber Breaks down dietary fiber that our own enzymes can't. 1 of 5 strains can
- Can use lactose The sugar in milk and dairy.
Not seen in its lab tests: eat inulin.
All 13 capabilities and their evidence
| Capability | Verdict | Genome analysis | Lab tests | Published research |
|---|---|---|---|---|
| Can ferment fiber | Some strains | — | 1 of 5 strains · strip test | No papers |
| Can eat inulin | Not seen | — | 0 of 4 strains · strip test | No papers |
| Can use lactose | Can | — | 2 of 2 strains | No papers |
| Can make butyrate | Not checked | — | — | No papers |
| Can make propionate | Not checked | — | — | No papers |
| Can make lactic acid | Not checked | — | — | No papers |
| Can eat resistant starch | Not checked | — | — | No papers |
| Can eat pectin | Not checked | — | — | No papers |
| Can feed on gut mucus | Not checked | — | — | No papers |
| Can change bile acids | Not checked | — | — | No papers |
| Can make B vitamins | Not checked | — | — | No papers |
| Can make hydrogen sulfide | Not checked | — | — | No papers |
| Can make methane | Not checked | — | — | No papers |
AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0
In healthy guts
Found in under 1% of healthy people.
- largest Segatella copri 6.2%
- 2nd largest Phocaeicola vulgatus 5.0%
- 3rd largest Faecalibacterium prausnitzii 4.7%
- 4th largest Bacteroides uniformis 3.2%
- 5th largest Agathobacter rectalis 2.5%
- 6th largest Alistipes putredinis 2.3%
- 7th largest Bifidobacterium longum 2.1%
- 8th largest Ruminococcus bromii 1.8%
- Heyndrickxia coagulans under 0.01%
- 2,169 other microbes, each a sliver 56.7%
- 15.6%
On average, a sliver, under 0.01% of the microbes in a healthy gut.
Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.
In conditions
In studies of how people live
“Higher” is the study’s measure: on average, a bigger share of gut bacteria across everyone in the group, carriers or not. It isn’t how many people carry it. An association the authors report, measured once per person. It doesn’t mean a diet changes this microbe, or that the microbe affects health.
Recent research
Strains studied
How much each strain has been studied in people, not whether it works. Many trials test a strain inside a blend, so those are counted apart, and reviews are summaries of trials, so they're never counted as more trials.
11 strains of H. coagulans are named on product labels. 0 have human trials; 11 have none found yet, including MTCC 5856, which is in 219 products.
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No human trials found yet
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No human trials found yet
H. coagulans SNZ-1969
In 41 products →No human trials found yet
H. coagulans IS-2
In 28 products →No human trials found yet
H. coagulans SC-208
In 14 products →No human trials found yet
H. coagulans BC30
In 2 products →No human trials found yet
H. coagulans GBl-30
In 2 products →No human trials found yet
H. coagulans Uni-BactCF-15
In 2 products →No human trials found yet
H. coagulans ATCC 7050
In 1 product →No human trials found yet
H. coagulans BC99
In 1 product →No human trials found yet
H. coagulans BCP92
In 1 product →No human trials found yet
Human trials, meta-analyses and systematic reviews naming the strain · animal and lab studies not counted · Data sources