Randomized trial Nutrients · 2026 Sourdough Bread and Baker's Yeast Bread Affect Gut Symptoms and Targeted Gut Microbial Taxa Differently: A Randomised Controlled Trial. Watters SIN, Henriksen C, Gjøvik M, et al. Alistipes putredinisAlistipes shahiiBifidobacterium adolescentisBifidobacterium longum +1 more PubMed ↗
Randomized trial Journal of gastroenterology and hepatology · 2026 Consolidation Therapy of Probiotics With Rifaximin Prevent Relapse in Rifaximin-Responsive Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Randomized Clinical Trial. Zhong J, Xu Z, Chen W, et al. Bacillus subtilisEnterococcus faeciumFaecalibacterium PubMed ↗
Randomized trial Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026 [Preventive effect of Saccharomyces boulardii combined with Bifidobacterium quadruple viable preparation on antibiotic-associated diarrhea in infants and young children: a prospective randomized controlled study]. Chang YY, Lu TL, Lu M, et al. Saccharomyces cerevisiae PubMed ↗
Review Microbiological research · 2026 From composition to function: Translating porcine gut microbiota research into strategies for improving intestinal health. Yi L, Shi W, Jia H, et al. BacteroidesFaecalibacterium PubMed ↗
Observational BMC microbiology · 2026 Metagenomic profiling of gut microbiome in post-cholecystectomy patients with diarrhea: a nested case-control study. Ye J, Mao P, Li B, et al. Bacteroides intestinalisCoprococcus comesSegatella copriBlautia PubMed ↗
Randomized trial Journal of visualized experiments · 2026 Age-stratified Evaluation Of Saccharomyces boulardii In A Pediatric Randomized Controlled Trial And Adult Observational Study of Infectious Enteritis. Lou Y, Wang Q, Xing X Saccharomyces cerevisiae PubMed ↗
Randomized trial International microbiology · 2026 Bifidobacterium breve PRL2020 mitigates antibiotic-induced gut symptoms and dysbiosis in children treated with amoxicillin or amoxicillin-clavulanate. Di Pierro F, Carugno A, Baggi E, et al. Bifidobacterium breve PubMed ↗
Randomized trial Diabetes, obesity & metabolism · 2026 Bifidobacterium bifidum G9-1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open-Label, Randomized Controlled Trial (Binary STAR Study). Kobayashi G, Hashimoto Y, Matsuyama T, et al. Bifidobacterium bifidum PubMed ↗
Review Archives of microbiology · 2026 Divergent mechanistic pathways of diarrheagenic bacterial infections at the host-microbiota interface: a review. Bayode MT, Olawale OE, Olusola-Makinde OO Escherichia coli PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Comparative metagenomic analysis of diarrheal and non-diarrheal gut microbiome delineating the identification of prospective prognostic markers and probiotics to protect from diarrhea: a brief report. De R, Kanungo S, Mukhopadhyay AK, et al. Segatella copri PubMed ↗
Randomized trial Beneficial microbes · 2026 Effects of a Bacillus subtilis HU58 and Heyndrickxia faecalis SC208 spore-forming probiotic formula on gastrointestinal health: results of a randomised, double-blind, placebo-controlled pilot study. Sorensen K, Khanna S, Porwal A, et al. Bacillus subtilisHeyndrickxia coagulans PubMed ↗
Randomized trial Scientific reports · 2026 Probiotic intervention not beneficial to prevent antibiotic-associated diarrhea in absence of antibiotic-induced microbiome disruption. Merenstein D, Grant-Beurmann S, Sanders ME, et al. Bifidobacterium animalis PubMed ↗
Review Terapevticheskii arkhiv · 2026 [Probiotics' position in clinical practice: focus on the combination of Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12). A review]. Gorelov AV, Kozlov RS, Andreeva IV, et al. Bifidobacterium animalisLactobacillus acidophilus PubMed ↗
Review International journal of molecular sciences · 2026 Enteric Infections, Dysbiosis, and Metabolic Dysfunction: The Role of Diarrheagenic Pathogens in Insulin Resistance. Zermeño-Ruiz M, Gutierrez-Gutierrez F, Anaya-Ambriz EJ, et al. Escherichia coli PubMed ↗
Systematic review Journal of pediatric gastroenterology and nutrition · 2026 Systematic review: Limosilactobacillus reuteri DSM 17938 for preventing antibiotic-associated diarrhoea in children. Szajewska H, Kołodziej M, Zalewski BM, et al. Limosilactobacillus reuteri PubMed ↗
Randomized trial Nature communications · 2025 Gut Prevotella stercorea associates with protection against infection in rural African children. Ofordile O, Pereira DIA, Prentice AM, et al. Escherichia coli PubMed ↗
Review Current opinion in clinical nutrition and metabolic care · 2025 An update on probiotics in paediatrics. Zemła M, Kotowska-Bąbol M, Szajewska H Bifidobacterium animalisLacticaseibacillus rhamnosusLimosilactobacillus reuteriSaccharomyces cerevisiae +1 more PubMed ↗
Randomized trial Arquivos de gastroenterologia · 2025 EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS. DE Souza GC, Araujo Filho HB, DE Oliveira CZ, et al. Bifidobacterium animalisBifidobacterium bifidumLacticaseibacillus paracaseiLactobacillus acidophilus PubMed ↗
Randomized trial The American journal of gastroenterology · 2025 Efficacy and Safety of Gelatin Tannate and Tyndallized Acid Lactic Bacteria in Adults With Chronic Diarrhea and Altered Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled Study. Santos J, Iordache A, Manolache M Akkermansia muciniphilaFaecalibacterium prausnitzii PubMed ↗
Randomized trial Pediatric research · 2025 Saccharomyces boulardii's impact on pediatric diarrhea-predominant irritable bowel syndrome: animal model findings. Jin X, Guo P, Jin X, et al. Saccharomyces cerevisiae PubMed ↗
Meta-analysis The Tohoku journal of experimental medicine · 2025 Live Combined Bacillus Subtilis and Enterococcus Faecium for the Treatment and Prevention of Antibiotic-Associated Diarrhea: A RCT-Based Meta-Analysis. Zhang N, Chen Y, Shen Z Bacillus subtilisEnterococcus faecium PubMed ↗
Randomized trial Scientific reports · 2025 Impact of Enterococcus faecium 129 BIO 3B-R on Helicobacter pylori eradication therapy side effects in adult patients: a randomized, double-blind, placebo-controlled study. Tokunaga E, Inoue J, Asaji N, et al. Enterococcus faecium PubMed ↗
Randomized trial Scientific reports · 2025 High-dose multi-strain Bacillus probiotics enhance treatment and reduce antibiotic usage in children with persistent diarrhea through immune and microbiota modulation. Dang HT, Phung TTB, Tran DM, et al. Lacticaseibacillus rhamnosus PubMed ↗
Observational European journal of pediatrics · 2025 Fecal gut microbiome alterations and its association with lactose intolerance in children with rotavirus infection-related diarrhea. Ye Q, Zhang Z, Chen T, et al. Mediterraneibacter gnavus PubMed ↗
Review The Journal of nutrition · 2025 The Potential and Underlying Mechanisms of Punicalagin in Mitigating Enterotoxigenic Escherichia coli-Induced Diarrhea. Li XG, Zhao X, Zheng J, et al. Escherichia coli PubMed ↗
Meta-analysis Food & function · 2025 The effects of Lacticaseibacillus rhamnosus GG supplementation on gastrointestinal and respiratory outcomes: a systematic review and meta-analysis of randomized controlled trials. Hidayat K, Zhang L, Wei H, et al. Lacticaseibacillus rhamnosus PubMed ↗
Randomized trial Beneficial microbes · 2025 Effects of spore-forming probiotic Bacillus subtilis HU58™ in children with antibiotic-associated diarrhoea: a randomised, double-blind, placebo-controlled trial. Sorensen K, Jog P, Mankar S, et al. Bacillus subtilis PubMed ↗
Observational Inflammatory bowel diseases · 2025 The Fecal Microbiome of IBD Patients Is Less Divertible by Bowel Preparation Compared to Healthy Controls: Results From a Prospective Study. Blesl A, Binder L, Halwachs B, et al. Anaerobutyricum hallii PubMed ↗
Randomized trial Phytomedicine · 2025 Butyrate-producing commensal bacteria mediates the efficacy of herbal medicine JCM-16021 on abdominal pain in diarrhea-predominant irritable bowel syndrome: a randomized clinical trial. Zhai L, Zheng Y, Lo CW, et al. Agathobacter rectalis PubMed ↗
Review Open veterinary journal · 2025 Fermented purple onion (Allium cepa L.) and chive (Allium schoenoprasum) bulb extracts as antibiotic alternatives against toxin-carrying bacteria: In vitro and pathogenicity assessment in chickens. Hai PV, Hoa NX, Phuong HTA Bacillus subtilis PubMed ↗
Randomized trial Supportive care in cancer · 2025 Impact of Saccharomyces boulardii on acute gastrointestinal toxicities in patients undergoing pelvic radiotherapy for gynecologic cancers: a randomized controlled trial. Muangwong P, Tharavichitkul E, Thiennimitr P, et al. Saccharomyces cerevisiae PubMed ↗
Randomized trial European journal of pediatrics · 2025 Effect of Limosilactobacillus reuteri DSM17938 to prevent antibiotic-associated diarrhea in children: prospective, multi-center, randomized, placebo-controlled clinical trial (PEARL Study). Dinleyici EC, Ozen M, Guven S, et al. Limosilactobacillus reuteri PubMed ↗
Randomized trial Journal of tropical pediatrics · 2025 Efficacy of Lactobacillus reuteri DSM 17938 in Thai children with acute gastroenteritis and normal or mild dehydration in an outpatient setting: a randomized controlled trial. Rerksuppaphol L, Rerksuppaphol S Limosilactobacillus reuteri PubMed ↗
Meta-analysis Frontiers in cellular and infection microbiology · 2025 Efficacy and safety of Saccharomyces boulardii CNCM I-745 for the treatment of pediatric acute diarrhea in China: a systematic review and meta-analysis. McFarland LV, Li T Saccharomyces cerevisiae PubMed ↗
Randomized trial Scientific reports · 2025 Efficacy and safety of Saccharomyces boulardii as adjunct therapy with Vancomycin in treating Clostridioides difficile infection: A randomized controlled trial. Chitapanarux T, Wiracha U, Winichakoon P, et al. Saccharomyces cerevisiae PubMed ↗
Observational Nature communications · 2025 Association of distinct microbial and metabolic signatures with microscopic colitis. Chen AS, Kim H, Nzabarushimana E, et al. Bacteroides stercorisBlautia gluceraseaHaemophilus parainfluenzaeVeillonella dispar PubMed ↗
Review Nutrients · 2025 Undernutrition and Intestinal Infections in Children: A Narrative Review. Carvalho MCDC, Ribeiro SA, de Sousa LS, et al. Escherichia coli PubMed ↗
Randomized trial Critical care medicine · 2025 Diarrhea in Mechanically Ventilated Patients: A Nested Multicenter Substudy. Dionne JC, Johnstone J, Heels-Ansdell D, et al. Lacticaseibacillus rhamnosus PubMed ↗
Randomized trial Journal of pediatric gastroenterology and nutrition · 2025 Lactobacillus reuteri protectis DSM 17938 at high doses versus placebo in children with acute gastroenteritis in a Pediatric Emergency Department. Iramain R, Jara A, Ortiz J, et al. Limosilactobacillus reuteri PubMed ↗
Review Journal of gastroenterology and hepatology · 2024 The evidence for probiotics in the treatment of digestive disorders in the pediatric population. Gwee KA, Lee WRW, Chua Q, et al. Lacticaseibacillus rhamnosusLimosilactobacillus reuteriSaccharomyces cerevisiae PubMed ↗
Randomized trial Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024 [A prospective randomized controlled study on probiotics for the prevention of antibiotic-associated diarrhea in infants and young children]. Zhang SW, Zhi X, Wang MY, et al. Saccharomyces cerevisiae PubMed ↗
Observational The oncologist · 2024 Optimizing abemaciclib-induced diarrhea management in patients with breast cancer: a pragmatic 2-group study using a postbiotic microbiota stabilizer. De Sanctis R, Tiberio P, Jacobs F, et al. Lacticaseibacillus paracasei PubMed ↗
Observational Nature communications · 2024 Gut microbiota patterns associated with duration of diarrhea in children under five years of age in Ethiopia. Tesfaw G, Siraj DS, Abdissa A, et al. Faecalibacterium prausnitziiSegatella copri PubMed ↗
Randomized trial Gut microbes · 2024 Effects of postbiotics on chronic diarrhea in young adults: a randomized, double-blind, placebo-controlled crossover trial assessing clinical symptoms, gut microbiota, and metabolite profiles. Guo S, Ma T, Kwok LY, et al. Dysosmobacter welbionisFaecalibacterium prausnitzii PubMed ↗
Randomized trial Nature communications · 2024 Lactiplantibacillus plantarum P9 for chronic diarrhea in young adults: a large double-blind, randomized, placebo-controlled trial. Yang N, Ma T, Xie Y, et al. Lactiplantibacillus plantarum PubMed ↗
Review Expert opinion on pharmacotherapy · 2024 An update on the use of 'biotics' in pediatric infectious gastroenteritis. Wampers A, Huysentruyt K, Vandenplas Y Lacticaseibacillus rhamnosusLimosilactobacillus reuteriSaccharomyces cerevisiae PubMed ↗
Randomized trial Nutrients · 2024 Effectiveness of Psychobiotic Bifidobacterium breve BB05 in Managing Psychosomatic Diarrhea in College Students by Regulating Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled Trial. Wang Y, Wang Y, Ding K, et al. Bifidobacterium breveBacteroides PubMed ↗
Randomized trial Gut microbes · 2024 A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Srivastava S, Basak U, Naghibi M, et al. Bifidobacterium longum PubMed ↗
Randomized trial Spinal cord · 2024 Lactobacillus casei Shirota probiotic drinks reduce antibiotic associated diarrhoea in patients with spinal cord injuries who regularly consume proton pump inhibitors: a subgroup analysis of the ECLISP multicentre RCT. Wong S, Hirani SP, Forbes A, et al. PubMed ↗
Randomized trial European journal of clinical nutrition · 2024 Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study. Chen K, Jin S, Ma Y, et al. Bifidobacterium animalisBifidobacterium breveCollinsella aerofaciens PubMed ↗