probiome Sign in
← Conditions Digestive system

Inflammatory bowel disease

Long-term inflammation of the gut, mainly Crohn's disease and ulcerative colitis.

Compared within 2 studies that had both: 39 people with inflammatory bowel disease and 155 healthy people. 21 microbes are less common in people with inflammatory bowel disease, and 1 more common.

A difference is an association: it doesn’t mean these microbes cause, prevent or treat inflammatory bowel disease.

Phylum

Searching opens both lists and shows only matching rows.

Less common in inflammatory bowel disease · 21

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Anaerostipes hadrus in 2 studies Healthy 90% inflammatory bowel disease 41%
  2. Coprococcus comes in 2 studies Healthy 66% inflammatory bowel disease 18%
  3. Anaerobutyricum soehngenii in 2 studies Healthy 64% inflammatory bowel disease 18%
  4. Blautia obeum in 2 studies Healthy 77% inflammatory bowel disease 31%
  5. Blautia faecis in 2 studies Healthy 85% inflammatory bowel disease 44%

More common in inflammatory bowel disease · 1

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Actinomyces sp. ICM47 in 2 studies Healthy 8.0% inflammatory bowel disease 23%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in Japan, the United States.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 297 microbes

Compared within studies that had both, but not listed above.

Studies disagree · 1

No meaningful difference · 296
PubMed · human studies and reviews first

Recent research

All research on it
  1. Review Reviews on environmental health · 2026
    Dietary patterns, gut microbiota, and gastrointestinal disorders: mechanistic insights into irritable bowel syndrome and inflammatory bowel disease.
    PubMed ↗
  2. Review Pathogens · 2026
    Deciphering the Implications of Escherichia coli in Inflammatory Bowel Disease: From Symbiont to Pathogen.
    PubMed ↗
  3. Review Microbiological research · 2026
    Bacterial extracellular vesicles in the oral-gut axis: Roles in periodontitis and inflammatory bowel disease.
    PubMed ↗
  4. Systematic review Pathogens · 2026
    The Role of Microbiota and Fecal Transplantation in Inflammatory Bowel Disease.
    PubMed ↗
  5. Review Antonie van Leeuwenhoek · 2026
    Redrawing the gut map: evolving probiotic approaches to microbiota modulation in inflammatory bowel disease.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 324 linked papers, last 10 years