Ruminococcus bicirculans (ex Wegman et al. 2014)

No reference ID-gene sequence in NCBI yet Data sources

NCBI now calls it Ruminococcus bicirculans.

Healthy guts55%

Samples11,696

Products0

Genome

No reference genome in NCBI yet Data sources

Lab traits Cell shape: not yet known

Capabilities, not measurements of anyone's gut

What it can do

Eats

Can ferment fiber Breaks down dietary fiber that our own enzymes can't.

Not seen in its genomes: make butyrate, make propionate, make lactic acid, eat inulin, eat resistant starch, eat pectin, use lactose, feed on gut mucus, change bile acids, make B vitamins, make hydrogen sulfide, make methane.

All 13 capabilities and their evidence

Capability	Verdict	Genome analysis	Lab tests	Published research
Can make butyrate	Not seen	0 of 6 genomes	—	No papers
Can make propionate	Not seen	0 of 6 genomes	—	No papers
Can make lactic acid	Not seen	0 of 6 genomes	—	No papers
Can ferment fiber	Can	6 of 6 genomes	—	No papers
Can eat inulin	Not seen	0 of 6 genomes	—	No papers
Can eat resistant starch	Not seen	0 of 6 genomes	—	No papers
Can eat pectin	Not seen	0 of 6 genomes	—	No papers
Can use lactose	Not seen	0 of 6 genomes	—	No papers
Can feed on gut mucus	Not seen	0 of 6 genomes	—	No papers
Can change bile acids	Not seen	0 of 6 genomes	—	No papers
Can make B vitamins	Not seen	0 of 6 genomes	—	No papers
Can make hydrogen sulfide	Not seen	0 of 6 genomes	—	No papers
Can make methane	Not seen	0 of 6 genomes	—	No papers

AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0

What’s typical · a description, not a comparison

In healthy guts

Everyone · 12,213 people · 129 studies

How common

Found in 55% of healthy people.

How big a slice of the gut

largest Segatella copri 6.2%
2nd largest Phocaeicola vulgatus 5.0%
3rd largest Faecalibacterium prausnitzii 4.7%
4th largest Bacteroides uniformis 3.2%
5th largest Agathobacter rectalis 2.5%
6th largest Alistipes putredinis 2.3%
7th largest Bifidobacterium longum 2.1%
8th largest Ruminococcus bromii 1.8%
⋮
top 30 Ruminococcus bicirculans (ex Wegman et al. 2014) 0.8%
2,169 other microbes, each a sliver 55.9%
15.6%

On average, 0.8% of the microbes in a healthy gut: among the 30 largest slices.

By age and sex

Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.

By age

367 people · 4.1% carry it 0.03% of the microbes top 25%

198 people · 5 studies 56% carry it 0.9% of the microbes top 20

57 people · 37% carry it 0.4% of the microbes top 40

1,283 people · 27 studies 62% carry it 0.6% of the microbes top 30

142 people · 15 studies 63% carry it 0.6% of the microbes top 40

By sex

2,063 people · 59% carry it 0.8% of the microbes top 30

1,530 people · 29 studies 56% carry it 0.7% of the microbes top 40

Compared within studies that had both

In conditions

Compared with healthy people in the same studies, it’s less common in 10 conditions and more common in none. Only studies that had both are counted.

A difference is an association: it doesn’t mean this microbe causes, prevents or treats any of these.

Strongest first, then the biggest gap · Each figure is 10 people

Crohn's disease 1,313 people · 8 studies Less common in people with it Healthy 57% With it 31%
Chronic fatigue syndrome 302 people · 3 studies Less common in people with it Healthy 65% With it 46%
Ulcerative colitis 820 people · 7 studies Less common in people with it Healthy 58% With it 41%
Parkinson's disease 339 people · 6 studies Less common in people with it Healthy 62% With it 50%
Colorectal cancer 475 people · 10 studies Less common in people with it Healthy 62% With it 52%
Neuroblastoma 95 people · 2 studies Less common in people with it Healthy 55% With it 35%
Cystic fibrosis 52 people · 1 study Less common in people with it Healthy 40% With it 0%
Diarrhea 65 people · 1 study Less common in people with it Healthy 60% With it 7.7%
Campylobacter infections 26 people · 1 study Less common in people with it Healthy 36% With it 3.8%
High blood pressure 50 people · 1 study Less common in people with it Healthy 70% With it 44%

PubMed · human studies and reviews first

Recent research

No recent human studies or reviews yet. Probiome follows PubMed for the few hundred most-studied microbes; rarer species often only show up in large surveys. Search PubMed for this species ↗

Ruminococcus bicirculans (ex Wegman et al. 2014)

What it can do

In healthy guts

Where these numbers come from

In conditions

Where these numbers come from

Also compared · 46 conditions

No meaningful difference · 46

Recent research