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Systemic lupus erythematosus

Compared within 3 studies that had both: 62 people with systemic lupus erythematosus and 116 healthy people. 3 genera are less common in people with systemic lupus erythematosus, and 1 more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat systemic lupus erythematosus. GMrepo reports this group at the genus level only, so these are genera, not species.

Phylum

Searching opens both lists and shows only matching rows.

Less common in systemic lupus erythematosus · 3

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Ruminococcus genus in 3 studies Healthy 92% systemic lupus erythematosus 69%
  2. Muribaculaceae genus in 3 studies Healthy 30% systemic lupus erythematosus 9.7%
  3. Marvinbryantia genus in 3 studies Healthy 28% systemic lupus erythematosus 11%

More common in systemic lupus erythematosus · 1

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Thomasclavelia genus in 3 studies Healthy 30% systemic lupus erythematosus 60%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China, France.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 143 genera

Compared within studies that had both, but not listed above.

Studies disagree · 1

  • Dialister fewer in 2 · more in 1 · 3 studies

No meaningful difference · 142
PubMed · human studies and reviews first

Recent research

All research on it
  1. Observational Clinical rheumatology · 2025
    Exploring the gut microbiome in systemic lupus erythematosus: metagenomic and metabolomic insights into a new pro-inflammatory bacteria Clostridium scindens.
    PubMed ↗
  2. Systematic review Autoimmunity reviews · 2025
    Systemic lupus erythematosus and the gut microbiome: To look forward is to look within - A systematic review and narrative synthesis.
    PubMed ↗
  3. Observational Medical sciences · 2025
    Association of Gut Dysbiosis with Disease Phenotype and Treatment in Systemic Lupus Erythematosus.
    PubMed ↗
  4. Randomized trial Iranian journal of allergy, asthma, and immunology · 2025
    The Effect of Probiotic Yogurt Containing Lactobacillus rhamnosus and Bifidobacterium bifidum on Disease Activity and Disability in Patients with Systemic Lupus Erythematosus: A Randomized Controlled Trial.
    PubMed ↗
  5. Randomized trial Journal of food science · 2024
    Impact of synbiotics on disease activity in systemic lupus erythematosus: Results from a randomized clinical trial.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 25 linked papers, last 10 years