probiome Sign in
← Conditions Infections Genus-level

Hand, foot and mouth disease

Compared within 2 studies that had both: 34 people with hand, foot and mouth disease and 29 healthy people. 6 genera are less common in people with hand, foot and mouth disease, and 12 more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat hand, foot and mouth disease. GMrepo reports this group at the genus level only, so these are genera, not species.

Phylum

Searching opens both lists and shows only matching rows.

Less common in hand, foot and mouth disease · 6

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Caballeronia genus in 2 studies Healthy 41% hand, foot and mouth disease 0%
  2. Dubosiella genus in 2 studies Healthy 71% hand, foot and mouth disease 12%
  3. Pseudoxanthomonas genus in 2 studies Healthy 32% hand, foot and mouth disease 0%
  4. Pseudomonas genus in 2 studies Healthy 62% hand, foot and mouth disease 15%
  5. Fusicatenibacter genus in 2 studies Healthy 81% hand, foot and mouth disease 41%

More common in hand, foot and mouth disease · 12

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Anaerovibrio genus in 2 studies Healthy 0% hand, foot and mouth disease 71%
  2. Fenollaria genus in 2 studies Healthy 0% hand, foot and mouth disease 62%
  3. Porphyromonas genus in 2 studies Healthy 0% hand, foot and mouth disease 62%
  4. Negativicoccus genus in 2 studies Healthy 0% hand, foot and mouth disease 44%
  5. Peptoniphilus genus in 2 studies Healthy 2.9% hand, foot and mouth disease 56%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 104 genera

Compared within studies that had both, but not listed above.

Studies disagree · 12

No meaningful difference · 92
PubMed · human studies and reviews first

Recent research

All research on it
  1. Current microbiology · 2023
    Gut Microbiota in Children with Hand Foot and Mouth Disease on 16S rRNA Gene Sequencing.
    PubMed ↗
  2. BMC infectious diseases · 2021
    Intestinal microbiota has important effect on severity of hand foot and mouth disease in children.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 2 linked papers, last 10 years