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← Conditions Immune systemKidney, urinary and reproductive Genus-level

IgA nephropathy

Compared within 2 studies that had both: 54 people with IgA nephropathy and 40 healthy people. 1 genus is less common in people with IgA nephropathy, and 2 more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat IgA nephropathy. GMrepo reports this group at the genus level only, so these are genera, not species.

Phylum

Searching opens both lists and shows only matching rows.

Less common in IgA nephropathy · 1

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Paraprevotella genus in 2 studies Healthy 76% IgA nephropathy 35%

More common in IgA nephropathy · 2

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Rothia genus in 2 studies Healthy 5.2% IgA nephropathy 39%
  2. Acinetobacter genus in 2 studies Healthy 30% IgA nephropathy 59%

As many carry these · 1 the amount differs

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Streptococcus genus in 2 studies Healthy 91% IgA nephropathy 100%

    Carriers have more, in 2 of 2 studies (0.80% → 1.1% of their gut microbes).

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 125 genera

Compared within studies that had both, but not listed above.

Studies disagree · 1

No meaningful difference · 124
PubMed · human studies and reviews first

Recent research

All research on it
  1. Review Microbial biotechnology · 2026
    Potential Roles of Escherichia coli in IgA Nephropathy: Evidence, Mechanistic Hypotheses and Microbiota-Targeted Strategies.
    PubMed ↗
  2. Observational Renal failure · 2026
    Regulatory effects of leflunomide on gut microecology during IgA nephropathy treatment.
    PubMed ↗
  3. Observational Scientific reports · 2025
    Reduced butyrate-producing bacteria and altered metabolic pathways in the gut microbiome of immunoglobulin A nephropathy patients.
    PubMed ↗
  4. Review Theranostics · 2025
    The evolving understanding of systemic mechanisms in organ-specific IgA nephropathy: a focus on gut-kidney crosstalk.
    PubMed ↗
  5. Observational Renal failure · 2024
    Characteristics and function of the gut microbiota in patients with IgA nephropathy via metagenomic sequencing technology.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 8 linked papers, last 10 years