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Autism spectrum disorder

Compared within 2 studies that had both: 123 people with autism spectrum disorder and 128 healthy people. 11 microbes are less common in people with autism spectrum disorder, and 3 more common.

A difference is an association: it doesn’t mean these microbes cause, prevent or treat autism spectrum disorder.

Phylum

Searching opens both lists and shows only matching rows.

Less common in autism spectrum disorder · 11

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Blautia massiliensis (ex Durand et al. 2017) in 2 studies Healthy 56% autism spectrum disorder 31%
  2. Lachnospiraceae bacterium AM48-27BH in 2 studies Healthy 25% autism spectrum disorder 8.1%
  3. [Eubacterium] siraeum in 2 studies Healthy 33% autism spectrum disorder 14%
  4. Frisingicoccus caecimuris in 2 studies Healthy 9.4% autism spectrum disorder under 1%
  5. Mediterraneibacter faecis in 2 studies Healthy 45% autism spectrum disorder 24%

More common in autism spectrum disorder · 3

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Alistipes indistinctus in 2 studies Healthy 21% autism spectrum disorder 50%
  2. Enterocloster alcoholdehydrogenati in 2 studies Healthy 2.4% autism spectrum disorder 15%
  3. Oxalobacter formigenes in 2 studies Healthy 3.1% autism spectrum disorder 15%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 389 microbes

Compared within studies that had both, but not listed above.

Studies disagree · 4

No meaningful difference · 385
PubMed · human studies and reviews first

Recent research

All research on it
  1. Randomized trial BMC psychiatry · 2026
    Comparison of clinical efficacy and gut microbiota characteristics in children with ASD treated with fecal microbiota transplantation and ketogenic diet.
    PubMed ↗
  2. Observational Psychiatry research · 2026
    Multi-cohort evidence for impaired microbial support of the methionine cycle in children with autism spectrum disorder.
    PubMed ↗
  3. Observational BMC microbiology · 2026
    Gut bacterial characteristics in children with autism spectrum disorder according to symptom severity: a cross-sectional study.
    PubMed ↗
  4. Randomized trial BMC pediatrics · 2026
    Kefir-derived probiotic mixture for children with autism spectrum disorder: a double-blind randomized clinical trial.
    PubMed ↗
  5. Observational Translational psychiatry · 2025
    Identifying gut microbiota composition disparities in autistic individuals and their unaffected siblings: correlations with clinical characteristics.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 56 linked papers, last 10 years