1. 
   Microbe Pseudomonadota

   Steroidobacter NameName close to Steroidobacterales
2. 
   Microbe Pseudomonadota

   Steroidobacteraceae NameName close to Steroidobacterales
3. Research The Journal of steroid biochemistry and molecular biology · 2019

   Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells.

   [Clostridium] scindens

   MeaningAbout Steroidobacterales
   PubMed ↗
4. Research Cell · 2024

   Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas.

   Eggerthella lenta

   MeaningAbout Steroidobacterales
   PubMed ↗
5. 
   Microbe Pseudomonadota

   Enterobacterales MeaningAbout Steroidobacterales
6. Research Nature microbiology · 2022

   A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria.

   Bacteroides thetaiotaomicron

   MeaningAbout Steroidobacterales
   PubMed ↗
7. Research Nutrients · 2024

   Investigating the Metabolism of Estrogens in Ligilactobacillus salivarius Strains Isolated from Human Milk and Vaginal Microbiota.

   Ligilactobacillus salivarius

   MeaningAbout Steroidobacterales
   PubMed ↗
8. Research Nature microbiology · 2025

   An expanded metabolic pathway for androgen production by commensal bacteria.

   [Clostridium] scindens

   MeaningAbout Steroidobacterales
   PubMed ↗
9. Research Journal of lipid research · 2018

   The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase.

   [Clostridium] scindens

   MeaningAbout Steroidobacterales
   PubMed ↗
10. Research Cancer research and treatment · 2022 Animal study

    Changes in Gut Microbiome upon Orchiectomy and Testosterone Administration in AOM/DSS-Induced Colon Cancer Mouse Model.

    Ruminococcus bromiiRomboutsia timonensisAkkermansia muciniphila

    MeaningAbout Steroidobacterales
    PubMed ↗
11. Research The Journal of biological chemistry · 2019

    Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from Bifidobacterium adolescentis strain L2-32.

    Bifidobacterium adolescentisEggerthella lenta[Clostridium] scindens

    MeaningAbout Steroidobacterales
    PubMed ↗
12. Research Journal of medical microbiology · 2022

    Longitudinal analysis of the impact of oral contraceptive use on the gut microbiome.

    Eubacterium ramulus

    MeaningAbout Steroidobacterales
    PubMed ↗
13. Research Advanced healthcare materials · 2026 Animal study

    Delivery System Based on Akkermansia Muciniphila Loaded Salidroside for the Treatment of Osteoporosis in Zebrafish Model.

    Akkermansia muciniphila

    MeaningAbout Steroidobacterales
    PubMed ↗
14. Research Journal of medicinal food · 2024

    Lactobacillus gasseri BNR17 Ameliorates Dexamethasone-Induced Muscle Loss in BALB/c Mice and C2C12 Myotubes.

    Lactobacillus gasseri

    MeaningAbout Steroidobacterales
    PubMed ↗
15. Research Nature communications · 2020

    Abiraterone acetate preferentially enriches for the gut commensal Akkermansia muciniphila in castrate-resistant prostate cancer patients.

    Akkermansia muciniphila

    MeaningAbout Steroidobacterales
    PubMed ↗
16. Research Cell reports. Medicine · 2025 Randomized trial

    Glucocorticoid-induced changes of the gut microbiota and metabolic markers in healthy young men: Outcome of a randomized controlled trial.

    Dysosmobacter welbionisAnaerotignum faecicola

    MeaningAbout Steroidobacterales
    PubMed ↗
17. Research Journal of cachexia, sarcopenia and muscle · 2025 Animal study

    Polygonati Rhizoma Prevents Glucocorticoid-Induced Growth Inhibition of Muscle via Promoting Muscle Angiogenesis Through Deoxycholic Acid.

    Collinsella aerofaciens

    MeaningAbout Steroidobacterales
    PubMed ↗
18. Research Frontiers in cellular and infection microbiology · 2023

    Hormonal drugs: Influence on growth, biofilm formation, and adherence of selected gut microbiota.

    Bifidobacterium longumEscherichia coliBacteroides fragilis

    MeaningAbout Steroidobacterales
    PubMed ↗
19. Research Biochemistry · 2026

    Gut Bacterial 20-Hydroxysteroid Dehydrogenases Modify Endogenous Glucocorticoids and Corticosteroid Drugs.

    Bifidobacterium adolescentis[Clostridium] scindens

    MeaningAbout Steroidobacterales
    PubMed ↗
20. Research Bulletin of experimental biology and medicine · 2024 Animal study

    Glucocorticoid Deflazacort Normalizes the Ultrastructure of Skeletal Muscles and the State of the Colon Microbiota in Dystrophin-Deficient Mice.

    Escherichia coli

    MeaningAbout Steroidobacterales
    PubMed ↗
21. Research Applied and environmental microbiology · 2026

    Identification of the C9-hydrogenase for 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid (9,17-DOHNA) and the 7α-dehydratase essential for initiating β-oxidation of the B-, C-, and D-rings in steroid degradation by Comamonas testosteroni TA441.

    [Clostridium] scindens

    MeaningAbout Steroidobacterales
    PubMed ↗
22. Research FEMS microbiology reviews · 2025 Review

    Clostridium scindens: history and current outlook for a keystone species in the mammalian gut involved in bile acid and steroid metabolism.

    [Clostridium] scindens

    MeaningAbout Steroidobacterales
    PubMed ↗
23. Research Frontiers in cellular and infection microbiology · 2026

    SSTDhunter: a curated gene database for investigating androgen producing potential in microbiota species.

    [Clostridium] scindens

    MeaningAbout Steroidobacterales
    PubMed ↗
24. Research Archives of gerontology and geriatrics · 2024 Review

    The molecular mechanisms of steroid hormone effects on cognitive function.

    Paraprevotella clara

    MeaningAbout Steroidobacterales
    PubMed ↗
25. Research The Journal of steroid biochemistry and molecular biology · 2025 Review

    Microbial modulation of digoxin bioavailability: A pharmacomicrobiome perspective on Eggerthella lenta's role in steroid-like drug metabolism and precision therapeutics.

    Eggerthella lenta

    MeaningAbout Steroidobacterales
    PubMed ↗
26. Research Gut microbes · 2024

    Clostridium innocuum, an opportunistic gut pathogen, inactivates host gut progesterone and arrests ovarian follicular development.

    [Clostridium] innocuum

    MeaningAbout Steroidobacterales
    PubMed ↗
27. Research Comprehensive physiology · 2026

    The Role of Fecal Microbiome Transplantation in Steroid Hyporesponsive Asthma.

    Faecalibacterium prausnitziiAkkermansia muciniphila

    MeaningAbout Steroidobacterales
    PubMed ↗

Research: PubMed, U.S. National Library of Medicine · citations link to PubMed