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Postmenopausal osteoporosis

Compared within 1 study that had both: 55 people with postmenopausal osteoporosis and 44 healthy people. No microbes less common in people with postmenopausal osteoporosis, and 1 more common.

A difference is an association: it doesn’t mean these microbes cause, prevent or treat postmenopausal osteoporosis.

Searching opens both lists and shows only matching rows.

Less common in postmenopausal osteoporosis · 0

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people

None compared.

More common in postmenopausal osteoporosis · 1

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Clostridiales bacterium KLE1615 in 1 study Healthy 16% postmenopausal osteoporosis 51%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 206 microbes

Compared within studies that had both, but not listed above.

No meaningful difference · 206
PubMed · human studies and reviews first

Recent research

All research on it
  1. Free radical biology & medicine · 2026
    The Metabolite indole-3-acetic acid of Bacteroides ovatus ameliorates ovariectomy-induced bone loss by activating AhR and inhibiting oxidative stress.
    PubMed ↗
  2. Journal of nanobiotechnology · 2026
    Engineered Akkermansia muciniphila extracellular vesicles for targeted delivery of miR-21-5p alleviate postmenopausal osteoporosis via PI3K-AKT pathway.
    PubMed ↗
  3. Turkish journal of medical sciences · 2026
    Comprehensive profiling of gut microbiota in postmenopausal osteoporosis.
    PubMed ↗
  4. Journal of leukocyte biology · 2025
    Gut-resident regulatory T cells (GTregs) play a pivotal role in maintaining bone health under postmenopausal osteoporotic conditions.
    PubMed ↗
  5. Randomized trial European journal of nutrition · 2022
    Bifidobacterium lactis Probio-M8 improves bone metabolism in patients with postmenopausal osteoporosis, possibly by modulating the gut microbiota.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 8 linked papers, last 10 years