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Cholestasis

Compared within 2 studies that had both: 69 people with cholestasis and 56 healthy people. 5 genera are less common in people with cholestasis, and 1 more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat cholestasis. GMrepo reports this group at the genus level only, so these are genera, not species.

Phylum

Searching opens both lists and shows only matching rows.

Less common in cholestasis · 5

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Dialister genus in 2 studies Healthy 82% cholestasis 32%
  2. Allisonella genus in 2 studies Healthy 21% cholestasis 2.9%
  3. Thomasclavelia genus in 2 studies Healthy 59% cholestasis 36%
  4. Faecalibacterium genus in 2 studies Healthy 78% cholestasis 59%
  5. Flavonifractor genus in 2 studies Healthy 63% cholestasis 44%

More common in cholestasis · 1

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Fusobacterium genus in 2 studies Healthy 0% cholestasis 19%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China, Germany.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 80 genera

Compared within studies that had both, but not listed above.

Studies disagree · 26

No meaningful difference · 54
PubMed · human studies and reviews first

Recent research

All research on it
  1. Systematic review Arquivos de gastroenterologia · 2026
    GUT MICROBIOTA ALTERATIONS IN RODENT MODELS OF CHOLESTASIS INDUCED BY BILE DUCT LIGATION: A SYSTEMATIC REVIEW.
    PubMed ↗
  2. Nature communications · 2026
    Pharmabiotics, Phocaeicola dorei, ameliorates cholestatic liver fibrosis by alleviating macrophage efferocytosis of neutrophils.
    PubMed ↗
  3. Frontiers in cellular and infection microbiology · 2025
    Identification and characterization of bile microbiota in patients with biliary obstructive diseases using next-generation sequencing of 16S rRNA and ITS.
    PubMed ↗
  4. Advanced science · 2024
    Clostridium Scindens Protects Against Vancomycin-Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR-FGF15/19 Signaling.
    PubMed ↗
  5. Microbes and infection · 2023
    A novel gut microbiome-immune axis influencing pathology in HCMV infected infants with neonatal cholestasis.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 15 linked papers, last 10 years