Systematic review Arquivos de gastroenterologia · 2026 GUT MICROBIOTA ALTERATIONS IN RODENT MODELS OF CHOLESTASIS INDUCED BY BILE DUCT LIGATION: A SYSTEMATIC REVIEW. Calixto SL, Macedo ACLP, Aguiar JAK Akkermansia muciniphilaEscherichia coli PubMed ↗
Nature communications · 2026 Pharmabiotics, Phocaeicola dorei, ameliorates cholestatic liver fibrosis by alleviating macrophage efferocytosis of neutrophils. Eom JA, Park IG, Hyun JY, et al. Phocaeicola dorei PubMed ↗
Frontiers in cellular and infection microbiology · 2025 Identification and characterization of bile microbiota in patients with biliary obstructive diseases using next-generation sequencing of 16S rRNA and ITS. Wang J, Wang Y, Cao J, et al. Klebsiella pneumoniae PubMed ↗
PloS one · 2025 Study on the relationship between microbial composition within obstructive biliary stents and the severity of obstruction and duration of stent placement. Sugawara I, Kawahara Y, Takayasu L, et al. Bifidobacterium animalis PubMed ↗
Advanced science · 2024 Clostridium Scindens Protects Against Vancomycin-Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR-FGF15/19 Signaling. Xiao J, Hou Y, Luo X, et al. [Clostridium] scindens PubMed ↗
Microbes and infection · 2023 A novel gut microbiome-immune axis influencing pathology in HCMV infected infants with neonatal cholestasis. Karandikar K, Bhonde G, Palav H, et al. Bifidobacterium breveVeillonella dispar PubMed ↗
Animal study NPJ biofilms and microbiomes · 2025 Synergistic effects of ferulic acid and wogonin on cholestatic liver injury via gut microbiota modulation. Luo X, Mao T, Wang X, et al. Alistipes putredinis PubMed ↗
Animal study International immunopharmacology · 2025 Short-chain fatty acids alleviate cholestatic liver injury by improving gut microbiota and bile acid metabolism. Lu H, Zhang M, Hu Y, et al. Akkermansia muciniphila PubMed ↗
Animal study NPJ biofilms and microbiomes · 2023 Impaired flux of bile acids from the liver to the gut reveals microbiome-immune interactions associated with liver damage. Leung H, Xiong L, Ni Y, et al. Escherichia coli PubMed ↗
Animal study Journal of hazardous materials · 2023 Multi-omics reveals 2-bromo-4,6-dinitroaniline (BDNA)-induced hepatotoxicity and the role of the gut-liver axis in rats. Deng F, Qin G, Chen Y, et al. Akkermansia muciniphila PubMed ↗
Animal study Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022 Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow. Marzano M, Fosso B, Colliva C, et al. Akkermansia muciniphila PubMed ↗
Animal study Biochimica et biophysica acta. Molecular basis of disease · 2021 Prevotella copri ameliorates cholestasis and liver fibrosis in primary sclerosing cholangitis by enhancing the FXR signalling pathway. Jiang B, Yuan G, Wu J, et al. Segatella copri PubMed ↗
Scientific reports · 2020 Gut Microbiota Dysbiosis Associated with Bile Acid Metabolism in Neonatal Cholestasis Disease. Li M, Liu S, Wang M, et al. Lactobacillus gasseriParabacteroides distasonis PubMed ↗
Gastroenterology · 2018 Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic γδ T-Cell Receptor-Positive Cells and Pathogenesis of Cholestatic Liver Disease. Tedesco D, Thapa M, Chin CY, et al. Lactobacillus gasseri PubMed ↗
Animal study Scientific reports · 2019 Cholestasis induced by bile duct ligation promotes changes in the intestinal microbiome in mice. Cabrera-Rubio R, Patterson AM, Cotter PD, et al. Faecalibacterium prausnitzii PubMed ↗