Randomized trial BMJ open · 2026 BLIS study: a feasibility randomised controlled trial assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis) in adults in England. Wilcox CR, Cleary DW, Augustine M, et al. Streptococcus salivarius PubMed ↗
Randomized trial European journal of pediatrics · 2026 Preventing otitis media and respiratory tract infections with the oral probiotic Streptococcus salivarius K12. Halley C, Honeywill C, Kang J, et al. Streptococcus salivarius PubMed ↗
Clinical trial Nutrients · 2026 Gut Microbiota Changes Following Aerobic Exercise in Malnourished Octogenarians: An Assessor-Blinded Intervention Study Stratified by Nutritional Status. Yang H, Li J, Ren S, et al. Faecalibacterium prausnitziiStreptococcus salivarius PubMed ↗
Observational Pancreatology · 2026 Analysis of gut microbiome dynamics in patients with type 1 autoimmune pancreatitis before and after glucocorticoid treatment. Zhang XD, Shen XN, Liu CX, et al. Dorea formicigeneransStreptococcus salivarius PubMed ↗
Observational Gut microbes · 2026 Strain-level translocation and enrichment dynamics of oral bacteria in the lower gastrointestinal tract of stunted children. Yersin S, Gody JC, Mazel F, et al. Streptococcus salivarius PubMed ↗
Observational BMC microbiology · 2026 Oral dryness related symptoms in radiation-treated head and neck cancer patients: a pilot study of oral microbiome composition and function. Mougeot JC, Beckman MF, Henry AA, et al. Haemophilus parainfluenzaeStreptococcus salivarius PubMed ↗
Review Ageing research reviews · 2026 Advocating gut-retina connection and microbiota mediated pathways in management of age-related macular degeneration: Preclinical to clinical perspective. Waghmare PV, Kolekar KA, Bashir B, et al. Bifidobacterium bifidumBifidobacterium breveBifidobacterium longumEnterococcus faecalis +3 more PubMed ↗
Randomized trial Frontiers in cellular and infection microbiology · 2026 Effect of probiotic lozenges on improvement in tympanometric classification within 12 weeks in children aged 3-6 years with adenoid hypertrophy and otitis media with effusion undergoing non-surgical management: a randomized controlled trial. Shi J, Liu Y, Chen X, et al. Streptococcus salivarius PubMed ↗
Randomized trial BMC infectious diseases · 2026 Effect of probiotic colonization on oral hygiene and ventilator-associated pneumonia in ICU patients: a triple-blind randomized controlled trial. Salehi A, Ebrahimzadeh F, Behzadfar A, et al. Streptococcus salivarius PubMed ↗
Randomized trial Probiotics and antimicrobial proteins · 2026 Probiotic-Containing Nanofiber-Based Dental Floss Suppresses Subgingival Red Complex Periopathogens: A Randomized Double-Blind Crossover Trial. Hromcik F, Holochova P, Bohm J, et al. Ligilactobacillus salivariusStreptococcus salivarius PubMed ↗
Review International journal of molecular sciences · 2025 A New Perspective on Nasal Microbiota Dysbiosis-Mediated Allergic Rhinitis: From the Mechanism of Immune Microenvironment Remodeling to Microbiota-Targeted Therapeutic Strategies. Du L, Cheng X, Liu B, et al. Streptococcus salivarius PubMed ↗
Clinical trial Frontiers in nutrition · 2025 Study to evaluate the safety and tolerability of Streptococcus salivarius eK12, a genetically modified strain derived from the oral probiotic S. salivarius K12: Results from a randomized, double-blind, placebo-controlled, parallel-group clinical trial. Di Pierro F, Bugti AA, Bano A, et al. Streptococcus salivarius PubMed ↗
Review Alzheimer's & dementia · 2025 Unraveling the oral microbiome's role in Alzheimer's disease: From pathophysiology to therapeutic potential. Rozenblum G, Ait-Aissa K, Zahran G, et al. Streptococcus salivarius PubMed ↗
Review Discover oncology · 2025 Understanding the potential of probiotics in oral cancer prevention: a short review on microbial modulation. Rivera C Ligilactobacillus salivariusStreptococcus salivarius PubMed ↗
Review Archives of microbiology · 2025 The role of probiotics in controlling oral biofilm formation and mitigating oral squamous-cell carcinoma risk. Naz SS, Zafar S Bifidobacterium animalisStreptococcus salivarius PubMed ↗
Review Folia microbiologica · 2025 Microbiota-based therapies in oral health and disorders. Salah AN, Doghish YA, Abbass SO, et al. Streptococcus salivarius PubMed ↗
Randomized trial The journal of contemporary dental practice · 2025 Oral Probiotic Containing Streptococcus salivarius K12 and Lactobacillus brevis CD2 for Preventing Bacterial Pneumonia in Severe COVID-19: Randomized Clinical Trial. Lauxen JR, Callegari-Jacques SM, Mombelli AS, et al. Streptococcus salivarius PubMed ↗
Review Journal of applied biomaterials & functional materials · 2025 Probiotics for caries prevention: A narrative review. Nizami MZI, Chu S, Chu S, et al. Streptococcus salivarius PubMed ↗
Observational Journal of gastroenterology · 2025 Development of gastric mucosa-associated microbiota in autoimmune gastritis with neuroendocrine tumors. Otani K, Nakatsu G, Fujimoto K, et al. Haemophilus parainfluenzaeStreptococcus salivariusVeillonella atypica PubMed ↗
Randomized trial Beneficial microbes · 2025 The impact of Bifidobacterium longum CCFM1112 on chronic constipation: a randomised, double-blind, placebo-controlled study. Liu W, Wang J, Xue Y, et al. Bifidobacterium longumAnaerobutyricum halliiStreptococcus salivarius PubMed ↗