Observational Gut · 2026 Gut microbiome signatures in colorectal neoplasia: a cross-sectional study across neoplasia stages and subtypes. Louca P, Manning S, Hackney E, et al. Mediterraneibacter faecis PubMed ↗
Review APMIS · 2026 Iron, Biofilm, and Colorectal Cancer: Mechanistic Insights Into Enterococcus faecalis Pathogenesis. Luthuli S, Scarpulla N, Bertolino L, et al. Enterococcus faecalis PubMed ↗
Review Frontiers in immunology · 2026 Intratumoral microbiota: implications for colorectal cancer pathogenesis and therapy. Liu J, Qi Z Escherichia coli PubMed ↗
Review Frontiers in immunology · 2026 From gut microbiota-driven mucosal barrier disruption to myeloid-dominant immunosuppressive niches in colorectal cancer. Lu N, Zhang L, Sun H, et al. Bacteroides fragilis PubMed ↗
Review Microbiological research · 2026 Mechanisms linking the gut microbiota to colorectal cancer development and progression. Zheng H, Zhang W, Pang Q, et al. Bacteroides fragilisEscherichia coliStreptococcus thermophilus PubMed ↗
Review Infection, genetics and evolution · 2026 Role of pks + Escherichia coli in colorectal cancer: Mechanisms, clinical evidence, and therapeutic perspective. Nasrollahian S, Halaji M, Bakeshloo PH, et al. Escherichia coli PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Cross-sectional gut microbiota and serum metabolite differences across clinically defined groups in colorectal cancer. Jiang Z, Li L, Long Q, et al. Phocaeicola plebeius PubMed ↗
Review Life sciences · 2026 Gut microbiota and metabolites in remodeling the tumor microenvironment and regulating immunotherapeutic efficacy in colorectal cancer. Gu M, Wang Z, Huang F, et al. Akkermansia muciniphila PubMed ↗
Observational British journal of cancer · 2026 Fecal immunochemical tests from population-based colorectal cancer screening programs support prospective microbiome cohorts. Byrd DA, Zouiouich S, Wahl D, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Journal of the Egyptian National Cancer Institute · 2026 Cholecystectomy-associated gut microbiota dysbiosis promotes colorectal carcinogenesis: from epidemiological controversy to FXR-centered mechanistic insights. Huang Z Bifidobacterium breveMediterraneibacter gnavus PubMed ↗
Observational Microbial biotechnology · 2026 Genomic Map of Escherichia coli and Single Nucleotide Polymorphism Markers in Colorectal Cancer. Xi Y, Liping Z, Yating X, et al. Escherichia coli PubMed ↗
Systematic review International journal of molecular sciences · 2026 The Hidden Link Between Intestinal Helminthiasis, Gut Microbiome Alterations, and Colorectal Cancer Risk: A Systematic Review. Shemfe DP, Mvubu NE, Naidoo P, et al. [Ruminococcus] torques PubMed ↗
Review Frontiers in immunology · 2026 The microbiota-metabolite-immune axis in colorectal cancer: mechanistic insights and emerging clinical applications. Sun B, Wang T Bacteroides fragilisEscherichia coli PubMed ↗
Observational Cell host & microbe · 2026 Long-lasting gut microbiome and fecal metabolome alterations after colorectal adenoma removal and their relationship to colorectal cancer. Nogal A, Wang K, Thompson KN, et al. Bilophila wadsworthiaFaecalibacterium prausnitziiFlavonifractor plautii PubMed ↗
Review Gut microbes · 2026 Gut microbiota and diet in colorectal cancer: Converging determinants of carcinogenesis. Thakur BK, Choudhury SR, Turpin W, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Observational Gastroenterology · 2026 Revealing the Antagonistic Interactions of Faecalibacterium prausnitzii and Bacteroides fragilis in Colorectal Cancer. Kong C, Jin Y, Guo F, et al. Bacteroides fragilisFaecalibacterium prausnitzii PubMed ↗
Review NPJ biofilms and microbiomes · 2026 Gut microbiome-driven colorectal cancer via immune, metabolic, neural, and endocrine axes reprogramming. Bautista J, Lamas-Maceiras M, Hidalgo-Tinoco C, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Clinical & translational oncology · 2026 Immune-microbiota crosstalk in colorectal cancer: mechanistic pathways, biomarkers, and translational therapeutics. Shekar P, Pradeep S, Shivamallu C, et al. Bacteroides fragilis PubMed ↗
Review International journal of medical sciences · 2026 Tumor-Promoting Gut Microbes in Colorectal Cancer: Mechanisms and Translational Perspectives. Yu Y, Zhao W, Yang M, et al. Bacteroides fragilisEnterococcus faecalisEscherichia coli PubMed ↗
Review International journal of molecular sciences · 2025 The Role of Gut Microbiota in Colorectal Cancer Pathogenesis: A Comprehensive Literature Review. Paduraru DN, Palcau AC, Dinca VG, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Observational Gene · 2025 Characterization of the gut microbiota in patients with stage III colorectal cancer: A case-control study. Diakité MT, Sun S, Somboro AM, et al. Escherichia coli PubMed ↗
Review Journal of physiological investigation · 2025 Infectious Carcinogens Derived from Intestinal Microflora: Mechanisms of Microbial Transitions from Eubionts to Pathobionts. Pai YC, Huang CY, Lin LY, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Observational Anaerobe · 2025 Strain-specific genetic signatures of enterotoxigenic Bacteroides fragilis (ETBF) reveal bft-2 as a candidate biomarker for colorectal cancer. Rezaei A, Taheri M, Alikhani MY, et al. Bacteroides fragilis PubMed ↗
Systematic review BMC gastroenterology · 2025 The pathobiont role of Akkermansia muciniphila in colorectal cancer: a systematic review. Soheilipour M, Noursina A, Nekookhoo M, et al. Akkermansia muciniphila PubMed ↗
Review NPJ biofilms and microbiomes · 2025 Harnessing gut microbiota for colorectal cancer therapy: from clinical insights to therapeutic innovations. Chen C, Su Q, Zi M, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Postgraduate medical journal · 2025 Mechanisms of intestinal flora in colorectal cancer. Li J, Liu L, Zhong X, et al. Bacteroides fragilisEnterococcus faecalisEscherichia coli PubMed ↗
Randomized trial The American journal of clinical nutrition · 2025 Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial. Sun E, Zhu X, Ness RM, et al. Faecalibacterium prausnitzii PubMed ↗
Review Probiotics and antimicrobial proteins · 2025 The Role of Next-Generation Probiotics in Colorectal Cancer Pathways: Mechanisms and Therapeutic Potential. Naz SS, Sabate Ortega J Akkermansia muciniphilaBacteroides fragilis PubMed ↗
Clinical trial Investigational new drugs · 2025 Phase 1/2, open-label study of oral bacterial supplementation (EDP1503) plus pembrolizumab in participants with advanced or metastatic microsatellite-stable colorectal cancer, triple-negative breast cancer, and checkpoint inhibitor-relapsed tumors. Wang JS, Arrowsmith ER, Beck JT, et al. Bifidobacterium animalis PubMed ↗
Review Studies in health technology and informatics · 2025 Unraveling the Role of Gut Microbiota in Colorectal Cancer: A Global Perspectives and Biomarkers as Early Screening Tool for Colorectal Cancer. Upadhyay U, Dhar E, Bomrah S, et al. Bacteroides fragilis PubMed ↗
Review Frontiers in cellular and infection microbiology · 2025 Anaerobic gut bacteria and their potential role in the initiation, exacerbation, and development of human colorectal cancer: a narrative review. Sabour S, Sadeghi Koupaei H, Ghasemi H, et al. Bacteroides fragilis PubMed ↗
Review Biomolecules · 2025 The Impact of the Microbiota on the Immune Response Modulation in Colorectal Cancer. Neagu AI, Bostan M, Ionescu VA, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Ageing research reviews · 2025 The role of intratumoral microbiome in the occurrence, proliferation, metastasis of colorectal cancer and its underlying therapeutic strategies. Liao K, Wen J, Liu Z, et al. Escherichia coli PubMed ↗
Review Biochimica et biophysica acta. Reviews on cancer · 2025 Gut microbiota as a mediator of cancer development and management: From colitis to colitis-associated dysplasia and carcinoma. Dan W, Xiong C, Zhou G, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review APMIS · 2025 Examining the Role of Virulence Proteins From Pathogenic Anaerobes in the Initiation of Colorectal Cancer. Gopalakrishnan V, Saravanan V, Mahendran MIMS, et al. Bacteroides fragilis PubMed ↗
Meta-analysis Journal of translational medicine · 2025 Cross-cohort analysis identifies shared gut microbial signatures and validates microbial risk scores for colorectal cancer. Zhang Y, Luo J, Chen K, et al. [Clostridium] symbiosumBacteroides fragilis PubMed ↗
Review Toxins · 2025 Biological Mechanisms of Enterotoxigenic Bacteroides fragilis Toxin: Linking Inflammation, Colorectal Cancer, and Clinical Implications. Jasemi S, Molicotti P, Fais M, et al. Bacteroides fragilis PubMed ↗
Review PeerJ · 2025 Advances in drug resistance and resistance mechanisms of four colorectal cancer-associated gut microbiota. Gan Y, Yang H, Wang M, et al. Bacteroides fragilisEnterococcus faecalisEscherichia coli PubMed ↗
Observational Nature medicine · 2025 Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer. Piccinno G, Thompson KN, Manghi P, et al. Faecalibacterium prausnitzii PubMed ↗
Observational International journal of medical sciences · 2025 Diagnostic Value of the Combined Detection of Microbiota, Multiple Inflammation-Related Indicators, Serum Lipid Indices, and Tumour Markers in Colorectal Polyps: A Case-Control Study. Zhang L, Xiao G, Su D, et al. Bacteroides ovatusMediterraneibacter gnavusParabacteroides distasonis PubMed ↗
Review Microbiological research · 2025 Illuminating prospects of probiotic Akkermansia muciniphila in intestinal inflammation and carcinogenesis. Zhang K, Dong Y, Ding Y, et al. Akkermansia muciniphila PubMed ↗
Review Chinese medical journal · 2025 Intestinal dysbiosis and colorectal cancer. Kang Z, Jiang S, Fang JY, et al. Bacteroides fragilis PubMed ↗
Review Trends in microbiology · 2025 Physiological drivers of pks+ E. coli in colorectal cancer. Jans M, Vereecke L Escherichia coli PubMed ↗
Observational mSystems · 2025 Temporal network analysis of gut microbiota unveils aging trajectories associated with colon cancer. Chen Z, Zhang Z, Nie BN, et al. Phocaeicola vulgatus PubMed ↗
Review International journal of molecular sciences · 2025 Gut Microbiota and Colorectal Cancer: A Balance Between Risk and Protection. Ionescu VA, Diaconu CC, Gheorghe G, et al. Bacteroides fragilisEscherichia coliFaecalibacterium prausnitzii PubMed ↗
Observational Virulence · 2025 Comprehensive analysis of faecal metagenomic and serum metabolism revealed the role of gut microbes and related metabolites in detecting colorectal lateral spreading tumours. Lin H, Chen Y, Zhou M, et al. Roseburia intestinalis PubMed ↗
Observational Cell host & microbe · 2025 Multi-cohort analysis reveals colorectal cancer tumor location-associated fecal microbiota and their clinical impact. Lin Y, Lau HC, Liu C, et al. Veillonella parvula PubMed ↗
Observational Polish journal of microbiology · 2025 Comparative Analysis of Microbiological Profiles and Antibiotic Resistance Genes in Subjects with Colorectal Cancer and Healthy Individuals. Li J, Zhu Y, Chang Q, et al. Alistipes finegoldiiAlistipes shahiiBifidobacterium bifidumBifidobacterium breve +1 more PubMed ↗
Review Molecular medicine reports · 2025 Advances in research on the intestinal microbiota in the mechanism and prevention of colorectal cancer (Review). Sun W, Ma S, Meng D, et al. Escherichia coli PubMed ↗
Meta-analysis Frontiers in cellular and infection microbiology · 2025 Prevalence of enterotoxigenic Bacteroides fragilis in patients with colorectal cancer: a systematic review and meta-analysis. Xia S, Ma L, Li H, et al. Bacteroides fragilis PubMed ↗