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← Conditions Bones, joints and muscles Genus-level

Spondyloarthritis

Compared within 1 study that had both: 24 people with spondyloarthritis and 17 healthy people. 2 genera are less common in people with spondyloarthritis, and none more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat spondyloarthritis. GMrepo reports this group at the genus level only, so these are genera, not species.

Phylum

Searching opens both lists and shows only matching rows.

Less common in spondyloarthritis · 2

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Butyricicoccus genus in 1 study Healthy 100% spondyloarthritis 33%
  2. Bilophila genus in 1 study Healthy 100% spondyloarthritis 38%

More common in spondyloarthritis · 0

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people

None compared.

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in the United States.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 58 genera

Compared within studies that had both, but not listed above.

No meaningful difference · 58
PubMed · human studies and reviews first

Recent research

All research on it
  1. Gut microbes · 2025
    IgG-seq identifies immune-reactive enteric bacteria in Crohn's disease with spondyloarthritis.
    PubMed ↗
  2. Observational Rheumatology · 2025
    16s RNA-based metagenomics reveal previously unreported gut microbiota associated with reactive arthritis and undifferentiated peripheral spondyloarthritis.
    PubMed ↗
  3. Scientific reports · 2023
    Colonoscopy aspiration lavages for mucosal metataxonomic profiling of spondylarthritis-associated gastrointestinal tract alterations.
    PubMed ↗
  4. Observational Clinical and experimental rheumatology · 2022
    The faecal microbiota is distinct in HLA-B27+ ankylosing spondylitis patients versus HLA-B27+ healthy controls.
    PubMed ↗
  5. Systematic review Seminars in arthritis and rheumatism · 2021
    Gut microbiota changes in patients with spondyloarthritis: A systematic review.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 8 linked papers, last 10 years