probiome Sign in
← Conditions Other Genus-level

Macular degeneration

Compared within 3 studies that had both: 59 people with macular degeneration and 44 healthy people. No genera less common in people with macular degeneration, and none more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat macular degeneration. GMrepo reports this group at the genus level only, so these are genera, not species.

Searching opens both lists and shows only matching rows.

Less common in macular degeneration · 0

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people

None compared.

More common in macular degeneration · 0

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people

None compared.

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China, Switzerland.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 103 genera

Compared within studies that had both, but not listed above.

No meaningful difference · 103
PubMed · human studies and reviews first

Recent research

All research on it
  1. Review Ageing research reviews · 2026
    Advocating gut-retina connection and microbiota mediated pathways in management of age-related macular degeneration: Preclinical to clinical perspective.
    PubMed ↗
  2. International journal of medical sciences · 2026
    Gut Microbiota Signatures and Potential Mediators in the Trajectory of Age-related Macular Degeneration: A Phased Atlas by Genetic Inference.
    PubMed ↗
  3. Investigative ophthalmology & visual science · 2023
    Metagenomic Sequencing Analysis Identifies Cross-Cohort Gut Microbial Signatures Associated With Age-Related Macular Degeneration.
    PubMed ↗
  4. Observational Scientific reports · 2017
    Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 4 linked papers, last 10 years