Observational JAMA network open · 2026 Probiotics and Risk of Death, Necrotizing Enterocolitis, and Sepsis in Very Preterm Infants. Mitha A, Söderquist Kruth S, Sinervo E, et al. Bifidobacterium animalisBifidobacterium longumStreptococcus thermophilus PubMed ↗
Observational PloS one · 2026 Integrated microbiomics and metabolomics analysis reveals distinct profiles in carbapenem-resistant Acinetobacter baumannii and Escherichia coli infections in Pancreatitis-associated sepsis. Zhu K, Hu H, Yang Z, et al. Escherichia coli PubMed ↗
Systematic review American journal of infection control · 2026 Flavonifractor plautii: A rare pathogen in sepsis and critical care---A systematic narrative review of literature. Kvernberg J, Rehn M, Johansen IS, et al. Flavonifractor plautii PubMed ↗
Randomized trial Zhonghua wei zhong bing ji jiu yi xue · 2025 [Effects of Yiqi Huoxue Jiedu formula on the gut microbiota in elderly patients with pulmonary-derived sepsis based on 16S rDNA sequencing: a multicenter prospective randomized double-blind controlled trial]. Chen R, Lai J, Zhong M, et al. Ligilactobacillus salivarius PubMed ↗
Meta-analysis The journal of maternal-fetal & neonatal medicine · 2025 Efficacy of probiotic supplementation in preventing necrotizing enterocolitis in preterm infants: a systematic review and meta-analysis. Abdullahi AM, Zhao S, Xu Y Bifidobacterium bifidum PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2024 Investigating gut microbiota-blood and urine metabolite correlations in early sepsis-induced acute kidney injury: insights from targeted KEGG analyses. Xu Y, Xu J, Zhu Y, et al. Bacteroides caccae PubMed ↗
Meta-analysis Pediatric research · 2023 Bifidobacterium infantis as a probiotic in preterm infants: a systematic review and meta-analysis. Batta VK, Rao SC, Patole SK Bifidobacterium longum PubMed ↗
Randomized trial The Pediatric infectious disease journal · 2023 Long Duration of Oral Care Using Mother's Own Milk Influences Oral Microbiota and Clinical Outcomes in Very-low-birthweight Infants: Randomized Controlled Trial. Thatrimontrichai A, Surachat K, Singkhamanan K, et al. Bifidobacterium bifidum PubMed ↗
Observational Critical care · 2022 The pathogens of secondary infection in septic patients share a similar genotype to those that predominate in the gut. Mu S, Xiang H, Wang Y, et al. Enterococcus faeciumKlebsiella pneumoniae PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2022 Association Between Gut Dysbiosis and Sepsis-Induced Myocardial Dysfunction in Patients With Sepsis or Septic Shock. Chen Y, Zhang F, Ye X, et al. Phocaeicola vulgatus PubMed ↗
Review Acta clinica Belgica · 2021 A case of Flavonifractor plautii blood stream infection in a severe burn patient and a review of the literature. Costescu Strachinaru DI, Gallez JL, Daras S, et al. Flavonifractor plautii PubMed ↗
Journal of microbiological methods · 2026 Comparison of human DNA depletion and bacterial enrichment methods from large blood volumes to improve bloodstream infection diagnosis. Wijen A, von Wintersdorff C, Lijnen A, et al. Klebsiella pneumoniae PubMed ↗
Frontiers in cellular and infection microbiology · 2026 Gut microbiota and serum metabolic profiles in patients with sepsis-induced cardiomyopathy and their association with the disease. Chen K, Lin J, Zhang Y, et al. [Clostridium] innocuum PubMed ↗
mSystems · 2026 Higher abundance of Faecalibacterium prausnitzii in the gut microbiome is associated with a lower risk of sepsis development among 6,372 individuals followed for 20 years. Diab H, Kullberg RFJ, Yeo L-F, et al. Faecalibacterium prausnitzii[Clostridium] symbiosum PubMed ↗
mSphere · 2026 Isolation of a highly virulent colibactin-positive tumor-promoting strain of Escherichia coli from the gut microbiota of an adult. Weis AM, Matthews OJ, Bell R, et al. Escherichia coli PubMed ↗
Cell host & microbe · 2026 Gut microbiota immaturity with DL-endopeptidase deficiency links antibiotic use to preterm late-onset sepsis. Shen W, Wang H, Wang J, et al. Enterococcus faecium PubMed ↗
Pathogens · 2026 Novel Insights on Clinical Outcomes Using Integrated Shotgun Metagenomic Profiling of the Gut Microbiome, Resistome, and Host Immune-Inflammatory Response in Hospitalized Patients with Decompensated Cirrhosis. Philips CA, Oommen TT, Theruvath AH, et al. Ligilactobacillus salivarius PubMed ↗
Probiotics and antimicrobial proteins · 2025 Assessment of Protective Role of Different Probiotic Strains against Bacterial and Endotoxin-Induced Sepsis in a Mouse Model. Sajjal S, Bilal HA, Zahra A, et al. Escherichia coliStreptococcus salivarius PubMed ↗
Scientific reports · 2025 Modulation of sepsis by Lacticaseibacillus rhamnosus and the potential role of short-chain fatty acid levels in feces and blood. Chancharoenthana W, Kamolratanakul S, Pinitchun C, et al. Klebsiella pneumoniae PubMed ↗
British journal of pharmacology · 2025 Angiotensin-(1-7) alleviates intestinal barrier dysfunction and dysbiosis in mice with polymicrobial sepsis. Wang J, Li J, Li Y, et al. Lactobacillus gasseri PubMed ↗
Computers in biology and medicine · 2025 AI-driven rapid identification of bacterial and fungal pathogens in blood smears of septic patients. Sroka-Oleksiak A, Pardyl A, Rymarczyk D, et al. Enterococcus faecium PubMed ↗
Cell reports · 2025 Bacterial metabolite patterns of infants receiving multi-strain probiotics and risk of late-onset sepsis. Waschina S, Pagel J, Seeger K, et al. Bifidobacterium longum PubMed ↗
Frontiers in immunology · 2025 Comprehensive characterization of multi-omics landscapes between gut microbial metabolites and the druggable genome in sepsis. Liu J, Li T, Xin L, et al. Akkermansia muciniphila PubMed ↗
Nutrients · 2025 Butyrate Producers in Very Low Birth Weight Infants with Neither Culture-Proven Sepsis nor Necrotizing Enterocolitis. Thatrimontrichai A, Praditaukrit M, Maneenil G, et al. Bacteroides fragilis PubMed ↗
Acta microbiologica et immunologica Hungarica · 2025 Detection of morphological variants of colistin-resistant Klebsiella pneumoniae associated with sepsis in Kerala, India. Paul M, Thomas S Klebsiella pneumoniae PubMed ↗
Pathogens and disease · 2025 Akkermansia muciniphila attenuates sepsis-induced immunosuppression by shaping endotoxin-tolerant macrophage phenotypes. Qian H, Zhao F Akkermansia muciniphila PubMed ↗
Neonatology · 2024 Gut Pathogen Colonization: A Risk Factor to Bloodstream Infections in Preterm Neonates Admitted in the Neonatal Intensive Care Unit - A Prospective Cohort Study. Iqbal F, Siva N, Shenoy PA, et al. Klebsiella pneumoniae PubMed ↗
Microbiology spectrum · 2024 Multi-omics analysis reveals the interplay between pulmonary microbiome and host in immunocompromised patients with sepsis-induced acute lung injury. Lu F, Huang T, Chen R, et al. Streptococcus salivarius PubMed ↗
Frontiers in cellular and infection microbiology · 2024 Gut microbes improve prognosis of Klebsiella pneumoniae pulmonary infection through the lung-gut axis. Tang Y, Chen L, Yang J, et al. Klebsiella pneumoniae PubMed ↗
Early human development · 2024 No differences were observed in the prevention of necrotizing enterocolitis and late-onset sepsis among preterm infants who received either single-species or multi-species probiotics. Korček P, Straňák Z Bifidobacterium bifidumBifidobacterium breveBifidobacterium longum PubMed ↗
Frontiers in immunology · 2024 The causality of gut microbiota on onset and progression of sepsis: a bi-directional Mendelian randomization analysis. Gao Y, Liu L, Cui Y, et al. [Ruminococcus] torques PubMed ↗
BMC microbiology · 2024 Gut microbiota composition and changes in patients with sepsis: potential markers for predicting survival. Luan F, Zhou Y, Ma X, et al. Escherichia coli PubMed ↗
Gut · 2023 Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis. Xie S, Li J, Lyu F, et al. Akkermansia muciniphila PubMed ↗
BMC pediatrics · 2023 Relationship between gut microbiota dysbiosis and immune indicator in children with sepsis. Lin X, Abdalla M, Yang J, et al. Bacteroides uniformisKlebsiella pneumoniaeLachnospira eligens PubMed ↗
Scientific reports · 2023 Effectiveness of a probiotic combination on the neurodevelopment of the very premature infant. Baucells BJ, Sebastiani G, Herrero-Aizpurua L, et al. Bifidobacterium bifidum PubMed ↗
American journal of critical care · 2023 Bloodstream Infections in Infants and Children With Congenital Heart Disease Undergoing Cardiac Surgery. Ward J, Herrera-Eguizabal J, Andersen K, et al. Enterococcus faecalis PubMed ↗
Immunity · 2023 Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation. Chen X, Wu R, Li L, et al. Parabacteroides merdae PubMed ↗
Frontiers in public health · 2023 Assessment of blood cultures and antibiotic susceptibility testing for bacterial sepsis diagnosis and utilization of results by clinicians in Benin: A qualitative study. Legba BB, Dougnon V, Koudokpon H, et al. Klebsiella pneumoniae PubMed ↗
Nature microbiology · 2022 Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Carvalho MJ, Sands K, Thomson K, et al. Escherichia coliKlebsiella pneumoniae PubMed ↗
International journal of molecular sciences · 2022 Candida Worsens Klebsiella pneumoniae Induced-Sepsis in a Mouse Model with Low Dose Dextran Sulfate Solution through Gut Dysbiosis and Enhanced Inflammation. Panpetch W, Phuengmaung P, Hiengrach P, et al. Klebsiella pneumoniae PubMed ↗
Scientific reports · 2022 Macrophage depletion alters bacterial gut microbiota partly through fungal overgrowth in feces that worsens cecal ligation and puncture sepsis mice. Hiengrach P, Panpetch W, Chindamporn A, et al. Enterococcus faecalisKlebsiella pneumoniae PubMed ↗
Microbiome · 2022 Gut microbiota-derived ursodeoxycholic acid from neonatal dairy calves improves intestinal homeostasis and colitis to attenuate extended-spectrum β-lactamase-producing enteroaggregative Escherichia coli infection. He Z, Ma Y, Yang S, et al. Escherichia coli PubMed ↗
Laboratory medicine · 2022 First Case of Bloodstream Infection Caused by Ruminococcus gnavus in an 85 Year Old Man in China. Fan X, Chen Y, Liu Y, et al. Mediterraneibacter gnavus PubMed ↗
mSphere · 2021 A 21-Year Survey of Escherichia coli from Bloodstream Infections (BSI) in a Tertiary Hospital Reveals How Community-Hospital Dynamics of B2 Phylogroup Clones Influence Local BSI Rates. Rodríguez I, Figueiredo AS, Sousa M, et al. Escherichia coli PubMed ↗
Animal study mBio · 2026 Ecology of protection: probiotic biogeography and sepsis prevention in the neonatal intestine. Hansen SC, Hamm CW, Singer JR, et al. Escherichia coliKlebsiella pneumoniae PubMed ↗
Animal study Frontiers in immunology · 2026 The microbiome protects against septic hyperinflammation and bacterial proliferation in a zebrafish model of blood infection with Escherichia coli and mycobacteria. Liu L, Koch BEV, Krekels EHJ, et al. Escherichia coli PubMed ↗
Animal study ACS infectious diseases · 2025 Bacterial Carbonic Anhydrase Inhibitor CAI0019 Demonstrates Efficacy in Enterococcus faecium Septicemic Peritonitis Mouse Model While Sparing the Microbiome. Abutaleb NS, Holly KJ, Metcalfe CK, et al. Enterococcus faecium PubMed ↗
Animal study CNS neuroscience & therapeutics · 2025 Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy. Gong B, Li F, Bai Y, et al. Akkermansia muciniphila PubMed ↗
Animal study Journal of controlled release · 2025 SpyTag-PEGylated probiotics delivering IL-1Ra modulate gut-lung crosstalk to mitigate septic lung injury. Yao Q, Liu T, Wen J, et al. Escherichia coli PubMed ↗
Animal study Nature microbiology · 2025 Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice. Udayan S, Floyd AN, John V, et al. Escherichia coli PubMed ↗