Observational Gut · 2026 Gut microbiome signatures in colorectal neoplasia: a cross-sectional study across neoplasia stages and subtypes. Louca P, Manning S, Hackney E, et al. Mediterraneibacter faecis PubMed ↗
Review APMIS · 2026 Iron, Biofilm, and Colorectal Cancer: Mechanistic Insights Into Enterococcus faecalis Pathogenesis. Luthuli S, Scarpulla N, Bertolino L, et al. Enterococcus faecalis PubMed ↗
Review Frontiers in immunology · 2026 Intratumoral microbiota: implications for colorectal cancer pathogenesis and therapy. Liu J, Qi Z Escherichia coli PubMed ↗
Review Frontiers in immunology · 2026 From gut microbiota-driven mucosal barrier disruption to myeloid-dominant immunosuppressive niches in colorectal cancer. Lu N, Zhang L, Sun H, et al. Bacteroides fragilis PubMed ↗
Review Microbiological research · 2026 Mechanisms linking the gut microbiota to colorectal cancer development and progression. Zheng H, Zhang W, Pang Q, et al. Bacteroides fragilisEscherichia coliStreptococcus thermophilus PubMed ↗
Review Infection, genetics and evolution · 2026 Role of pks + Escherichia coli in colorectal cancer: Mechanisms, clinical evidence, and therapeutic perspective. Nasrollahian S, Halaji M, Bakeshloo PH, et al. Escherichia coli PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Cross-sectional gut microbiota and serum metabolite differences across clinically defined groups in colorectal cancer. Jiang Z, Li L, Long Q, et al. Phocaeicola plebeius PubMed ↗
Review Life sciences · 2026 Gut microbiota and metabolites in remodeling the tumor microenvironment and regulating immunotherapeutic efficacy in colorectal cancer. Gu M, Wang Z, Huang F, et al. Akkermansia muciniphila PubMed ↗
Observational British journal of cancer · 2026 Fecal immunochemical tests from population-based colorectal cancer screening programs support prospective microbiome cohorts. Byrd DA, Zouiouich S, Wahl D, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Journal of the Egyptian National Cancer Institute · 2026 Cholecystectomy-associated gut microbiota dysbiosis promotes colorectal carcinogenesis: from epidemiological controversy to FXR-centered mechanistic insights. Huang Z Bifidobacterium breveMediterraneibacter gnavus PubMed ↗
Observational Microbial biotechnology · 2026 Genomic Map of Escherichia coli and Single Nucleotide Polymorphism Markers in Colorectal Cancer. Xi Y, Liping Z, Yating X, et al. Escherichia coli PubMed ↗
Systematic review International journal of molecular sciences · 2026 The Hidden Link Between Intestinal Helminthiasis, Gut Microbiome Alterations, and Colorectal Cancer Risk: A Systematic Review. Shemfe DP, Mvubu NE, Naidoo P, et al. [Ruminococcus] torques PubMed ↗
Review Frontiers in immunology · 2026 The microbiota-metabolite-immune axis in colorectal cancer: mechanistic insights and emerging clinical applications. Sun B, Wang T Bacteroides fragilisEscherichia coli PubMed ↗
Observational Cell host & microbe · 2026 Long-lasting gut microbiome and fecal metabolome alterations after colorectal adenoma removal and their relationship to colorectal cancer. Nogal A, Wang K, Thompson KN, et al. Bilophila wadsworthiaFaecalibacterium prausnitziiFlavonifractor plautii PubMed ↗
Review Gut microbes · 2026 Gut microbiota and diet in colorectal cancer: Converging determinants of carcinogenesis. Thakur BK, Choudhury SR, Turpin W, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Observational Gastroenterology · 2026 Revealing the Antagonistic Interactions of Faecalibacterium prausnitzii and Bacteroides fragilis in Colorectal Cancer. Kong C, Jin Y, Guo F, et al. Bacteroides fragilisFaecalibacterium prausnitzii PubMed ↗
Review NPJ biofilms and microbiomes · 2026 Gut microbiome-driven colorectal cancer via immune, metabolic, neural, and endocrine axes reprogramming. Bautista J, Lamas-Maceiras M, Hidalgo-Tinoco C, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Clinical & translational oncology · 2026 Immune-microbiota crosstalk in colorectal cancer: mechanistic pathways, biomarkers, and translational therapeutics. Shekar P, Pradeep S, Shivamallu C, et al. Bacteroides fragilis PubMed ↗
Review International journal of medical sciences · 2026 Tumor-Promoting Gut Microbes in Colorectal Cancer: Mechanisms and Translational Perspectives. Yu Y, Zhao W, Yang M, et al. Bacteroides fragilisEnterococcus faecalisEscherichia coli PubMed ↗
Review International journal of molecular sciences · 2025 The Role of Gut Microbiota in Colorectal Cancer Pathogenesis: A Comprehensive Literature Review. Paduraru DN, Palcau AC, Dinca VG, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Observational Gene · 2025 Characterization of the gut microbiota in patients with stage III colorectal cancer: A case-control study. Diakité MT, Sun S, Somboro AM, et al. Escherichia coli PubMed ↗
Review Journal of physiological investigation · 2025 Infectious Carcinogens Derived from Intestinal Microflora: Mechanisms of Microbial Transitions from Eubionts to Pathobionts. Pai YC, Huang CY, Lin LY, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Observational Anaerobe · 2025 Strain-specific genetic signatures of enterotoxigenic Bacteroides fragilis (ETBF) reveal bft-2 as a candidate biomarker for colorectal cancer. Rezaei A, Taheri M, Alikhani MY, et al. Bacteroides fragilis PubMed ↗
Systematic review BMC gastroenterology · 2025 The pathobiont role of Akkermansia muciniphila in colorectal cancer: a systematic review. Soheilipour M, Noursina A, Nekookhoo M, et al. Akkermansia muciniphila PubMed ↗
Review NPJ biofilms and microbiomes · 2025 Harnessing gut microbiota for colorectal cancer therapy: from clinical insights to therapeutic innovations. Chen C, Su Q, Zi M, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Postgraduate medical journal · 2025 Mechanisms of intestinal flora in colorectal cancer. Li J, Liu L, Zhong X, et al. Bacteroides fragilisEnterococcus faecalisEscherichia coli PubMed ↗
Randomized trial The American journal of clinical nutrition · 2025 Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial. Sun E, Zhu X, Ness RM, et al. Faecalibacterium prausnitzii PubMed ↗
Review Probiotics and antimicrobial proteins · 2025 The Role of Next-Generation Probiotics in Colorectal Cancer Pathways: Mechanisms and Therapeutic Potential. Naz SS, Sabate Ortega J Akkermansia muciniphilaBacteroides fragilis PubMed ↗
Clinical trial Investigational new drugs · 2025 Phase 1/2, open-label study of oral bacterial supplementation (EDP1503) plus pembrolizumab in participants with advanced or metastatic microsatellite-stable colorectal cancer, triple-negative breast cancer, and checkpoint inhibitor-relapsed tumors. Wang JS, Arrowsmith ER, Beck JT, et al. Bifidobacterium animalis PubMed ↗
Review Studies in health technology and informatics · 2025 Unraveling the Role of Gut Microbiota in Colorectal Cancer: A Global Perspectives and Biomarkers as Early Screening Tool for Colorectal Cancer. Upadhyay U, Dhar E, Bomrah S, et al. Bacteroides fragilis PubMed ↗
Review Frontiers in cellular and infection microbiology · 2025 Anaerobic gut bacteria and their potential role in the initiation, exacerbation, and development of human colorectal cancer: a narrative review. Sabour S, Sadeghi Koupaei H, Ghasemi H, et al. Bacteroides fragilis PubMed ↗
Review Biomolecules · 2025 The Impact of the Microbiota on the Immune Response Modulation in Colorectal Cancer. Neagu AI, Bostan M, Ionescu VA, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review Ageing research reviews · 2025 The role of intratumoral microbiome in the occurrence, proliferation, metastasis of colorectal cancer and its underlying therapeutic strategies. Liao K, Wen J, Liu Z, et al. Escherichia coli PubMed ↗
Review Biochimica et biophysica acta. Reviews on cancer · 2025 Gut microbiota as a mediator of cancer development and management: From colitis to colitis-associated dysplasia and carcinoma. Dan W, Xiong C, Zhou G, et al. Bacteroides fragilisEscherichia coli PubMed ↗
Review APMIS · 2025 Examining the Role of Virulence Proteins From Pathogenic Anaerobes in the Initiation of Colorectal Cancer. Gopalakrishnan V, Saravanan V, Mahendran MIMS, et al. Bacteroides fragilis PubMed ↗
Meta-analysis Journal of translational medicine · 2025 Cross-cohort analysis identifies shared gut microbial signatures and validates microbial risk scores for colorectal cancer. Zhang Y, Luo J, Chen K, et al. [Clostridium] symbiosumBacteroides fragilis PubMed ↗
Review Toxins · 2025 Biological Mechanisms of Enterotoxigenic Bacteroides fragilis Toxin: Linking Inflammation, Colorectal Cancer, and Clinical Implications. Jasemi S, Molicotti P, Fais M, et al. Bacteroides fragilis PubMed ↗
Review PeerJ · 2025 Advances in drug resistance and resistance mechanisms of four colorectal cancer-associated gut microbiota. Gan Y, Yang H, Wang M, et al. Bacteroides fragilisEnterococcus faecalisEscherichia coli PubMed ↗
Observational Nature medicine · 2025 Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer. Piccinno G, Thompson KN, Manghi P, et al. Faecalibacterium prausnitzii PubMed ↗
Observational International journal of medical sciences · 2025 Diagnostic Value of the Combined Detection of Microbiota, Multiple Inflammation-Related Indicators, Serum Lipid Indices, and Tumour Markers in Colorectal Polyps: A Case-Control Study. Zhang L, Xiao G, Su D, et al. Bacteroides ovatusMediterraneibacter gnavusParabacteroides distasonis PubMed ↗