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← Conditions Kidney, urinary and reproductive

Chronic kidney disease

Compared within 1 study that had both: 47 people with chronic kidney disease and 111 healthy people. 2 microbes are less common in people with chronic kidney disease, and 84 more common.

A difference is an association: it doesn’t mean these microbes cause, prevent or treat chronic kidney disease.

Phylum

Searching opens both lists and shows only matching rows.

Less common in chronic kidney disease · 2

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Roseburia faecis in 1 study Healthy 71% chronic kidney disease 40%
  2. Faecalibacillus intestinalis in 1 study Healthy 80% chronic kidney disease 55%

More common in chronic kidney disease · 84

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Hungatella hathewayi in 1 study Healthy 14% chronic kidney disease 75%
  2. Enterocloster citroniae in 1 study Healthy 6.3% chronic kidney disease 60%
  3. [Clostridium] innocuum in 1 study Healthy 32% chronic kidney disease 87%
  4. Neobittarella massiliensis (ex Bilen et al. 2018) in 1 study Healthy 9.0% chronic kidney disease 62%
  5. Eisenbergiella massiliensis in 1 study Healthy 1.8% chronic kidney disease 45%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in China.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 232 microbes

Compared within studies that had both, but not listed above.

No meaningful difference · 232
PubMed · human studies and reviews first

Recent research

All research on it
  1. Randomized trial Journal of diabetes investigation · 2026
    Effects of age, sex, and renal function on bowel movement-improving effects of Bifidobacterium bifidum G9-1 on constipation in patients with type 2 diabetes mellitus and chronic kidney disease: A prespecified subgroup analysis of the BIRDIE study.
    PubMed ↗
  2. Observational Renal failure · 2026
    Gut microbiota biomarkers of chronic kidney disease progression identified by 16S rDNA sequencing and machine learning.
    PubMed ↗
  3. Review Acta pharmacologica Sinica · 2026
    Gut microbiota and renal fibrosis: novel mechanistic insights and therapeutic potential.
    PubMed ↗
  4. Clinical trial Journal of diabetes investigation · 2026
    Efficacy of probiotics (Bifidobacterium bifidum G9-1) in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation: An exploratory, multicenter, open-label, single-arm study (BIRDIE study).
    PubMed ↗
  5. Clinical trial Journal of renal nutrition · 2025
    Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Fecal Microbiome and Host Metabolism.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 76 linked papers, last 10 years