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Familial adenomatous polyposis

Compared within 1 study that had both: 165 people with familial adenomatous polyposis and 310 healthy people. No genera less common in people with familial adenomatous polyposis, and none more common.

A difference is an association: it doesn’t mean these genera cause, prevent or treat familial adenomatous polyposis. GMrepo reports this group at the genus level only, so these are genera, not species.

Searching opens both lists and shows only matching rows.

Less common in familial adenomatous polyposis · 0

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people

None compared.

More common in familial adenomatous polyposis · 0

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people

None compared.

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in the United States.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 36 genera

Compared within studies that had both, but not listed above.

No meaningful difference · 36
PubMed · human studies and reviews first

Recent research

All research on it
  1. Animal study Microbiology spectrum · 2022
    Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene.
    PubMed ↗
  2. Animal study International journal of molecular sciences · 2021
    Microencapsulated Bifidobacterium bifidum and Lactobacillus gasseri in Combination with Quercetin Inhibit Colorectal Cancer Development in ApcMin/+ Mice.
    PubMed ↗
  3. Review Human genetics · 2020
    The microbiome, genetics, and gastrointestinal neoplasms: the evolving field of molecular pathological epidemiology to analyze the tumor-immune-microbiome interaction.
    PubMed ↗
  4. Science · 2018
    Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria.
    PubMed ↗
  5. Journal of Crohn's & colitis · 2017
    NOD2 Genetic Variants Predispose One of Two Familial Adenomatous Polyposis Siblings to Pouchitis Through Microbiome Dysbiosis.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 5 linked papers, last 10 years