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Neuroblastoma

Compared within 2 studies that had both: 95 people with neuroblastoma and 319 healthy people. 136 microbes are less common in people with neuroblastoma, and 29 more common.

A difference is an association: it doesn’t mean these microbes cause, prevent or treat neuroblastoma.

Phylum

Searching opens both lists and shows only matching rows.

Less common in neuroblastoma · 136

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Clostridiaceae bacterium AF18-31LB in 2 studies Healthy 65% neuroblastoma 22%
  2. Enterocloster hominis (ex Liu et al. 2021) in 2 studies Healthy 42% neuroblastoma 7.4%
  3. Faecalibacillus intestinalis in 2 studies Healthy 63% neuroblastoma 23%
  4. Lachnospira pectinoschiza in 2 studies Healthy 71% neuroblastoma 31%
  5. Mediterraneibacter faecis in 2 studies Healthy 66% neuroblastoma 26%

More common in neuroblastoma · 29

Strongest first, then the biggest gap · Each figure is 10 people Strongest first · Each figure is 10 people
  1. Eubacteriaceae bacterium CHKCI004 in 2 studies Healthy 0% neuroblastoma 13%
  2. Streptococcus peroris in 2 studies Healthy under 1% neuroblastoma 13%
  3. Lachnoclostridium sp. An118 in 2 studies Healthy 1.2% neuroblastoma 15%
  4. Claveliimonas bilis in 2 studies Healthy 9.5% neuroblastoma 30%
  5. Eubacteriaceae bacterium Marseille-Q4139 in 2 studies Healthy 7.6% neuroblastoma 25%

Where these numbers come from

Studies
Only GMrepo projects that had people with the condition and healthy people, 10 or more of each. Numbers come from those studies, never from pooling.Sampled in Italy.
How common
The share of people whose sample has any of it, in the people with the condition and in the healthy people of those same studies. Tested within studies (Cochran–Mantel–Haenszel, corrected for testing many microbes); a difference counts when it is clear and meaningful (Cohen’s h of 0.2 or more).
Strength word
Counted by code from how many studies point the same way: Seen again and again (3 or more, none clearly the other way), Seen more than once (2, the majority), Seen once (1, listed last). Where studies disagree, a row isn’t listed.
Each study
Tap a row for every study’s own numbers, and for how much carriers have.
Analysis
Our analysis of GMrepo data. GMrepo on Data sources · Read the rules

Also compared · 298 microbes

Compared within studies that had both, but not listed above.

No meaningful difference · 298
PubMed · human studies and reviews first

Recent research

All research on it
  1. Observational EBioMedicine · 2023
    Neuroblastoma is associated with alterations in gut microbiome composition subsequent to maternal microbial seeding.
    PubMed ↗
  2. Medical oncology · 2023
    Lysates from the probiotic bacterium Streptococcus thermophilus enhances the survival of T cells and triggers programmed cell death in neuroblastoma cells.
    PubMed ↗
  3. Nutrients · 2023
    Lactobacillus casei and Its Supplement Alleviate Stress-Induced Depression and Anxiety in Mice by the Regulation of BDNF Expression and NF-κB Activation.
    PubMed ↗
  4. Randomized trial Clinical nutrition · 2023
    Gut microbiota indole-3-propionic acid mediates neuroprotective effect of probiotic consumption in healthy elderly: A randomized, double-blind, placebo-controlled, multicenter trial and in vitro study.
    PubMed ↗
  5. Journal of the science of food and agriculture · 2023
    Neuroprotective effects of hydroponic ginseng fermented by Lactococcus lactis KC24 in oxidatively stressed SH-SY5Y cells.
    PubMed ↗

Source: PubMed, U.S. National Library of Medicine · 6 linked papers, last 10 years