Observational International journal of surgery · 2025 Microbial variations in the multibody sites of the pancreatic ductal adenocarcinoma patients. Zhu Y, Zhi M, Liang X, et al. Akkermansia muciniphilaFaecalibacterium prausnitzii PubMed ↗
Observational Cancer letters · 2025 Elevated levels of circulating microbial-associated uremic toxins are associated with metastatic duodenopancreatic neuroendocrine tumors in patients with Multiple Endocrine Neoplasia Type 1. Ballarò R, Wasylishen AR, Pieterman CRC, et al. Faecalibacterium prausnitziiKlebsiella pneumoniaeStreptococcus thermophilus PubMed ↗
Randomized trial Nutrients · 2024 Efficacy of 1-Kestose Supplementation in Patients with Pancreatic Ductal Adenocarcinoma: A Randomized Controlled Pilot Study. Nakaoka K, Ohno E, Kuramitsu K, et al. Escherichia coli PubMed ↗
Observational Cancer · 2023 Analysis of the fecal metagenome in long-term survivors of pancreas cancer. Kharofa J, Haslam D, Wilkinson R, et al. Akkermansia muciniphilaFaecalibacterium prausnitzii PubMed ↗
Review Nutrients · 2021 Pancreatic Cancer and Gut Microbiome-Related Aspects: A Comprehensive Review and Dietary Recommendations. Sobocki BK, Kaźmierczak-Siedlecka K, Folwarski M, et al. Akkermansia muciniphilaFaecalibacterium prausnitzii PubMed ↗
Science advances · 2026 Engineered probiotic Bifidobacterium for tumor-targeted pancreatic cancer therapy. Lee J, Yang K, Nowicki CA, et al. Bifidobacterium longum PubMed ↗
mBio · 2026 Potential mechanisms underlying Enterococcus faecalis-driven pancreatic cancer cell proliferation. Guan M, Guo X, Kong M, et al. Enterococcus faecalis PubMed ↗
Journal of extracellular vesicles · 2026 The Eubacterium Rectale Derived Extracellular Vesicles Alleviate Cancer Cachexia Induced Lipolysis by Inhibiting Macrophage Polarization. Wang J, Maitiabula G, Liu S, et al. Agathobacter rectalis PubMed ↗
Scientific reports · 2026 Multi-omics and network pharmacology reveal the mechanisms of Scutellaria barbata D.Don and Scleromitrion diffusum (Willd.) R.J.Wang against pancreatic cancer. Zhao Z, Yang Y, Zhang L, et al. Bacteroides caccae PubMed ↗
Cell host & microbe · 2026 Leveraging intratumoral probiotics for pancreatic cancer immunotherapy via xenophagy. Li B, Liu G, Zhu Y, et al. Bifidobacterium longum PubMed ↗
BMC cancer · 2025 Analysis of the predictive effect of gut microbiota changes on the occurrence of chemotherapy resistance in pancreatic cancer patients based on nomogram prediction models. Li Y, Liu S, Lai X, et al. Enterococcus faecalisEscherichia coli PubMed ↗
Frontiers in cellular and infection microbiology · 2025 Gut-to-tumor translocation of multidrug-resistant Klebsiella pneumoniae shapes the microbiome and chemoresistance in pancreatic cancer. Zhao L, Peng S, Ge M, et al. Klebsiella pneumoniaeAkkermansia muciniphila PubMed ↗
BMC microbiology · 2025 Oral and fecal microbiome alterations in pancreatic cancer: insights into potential diagnostic biomarkers. Tavanaeian S, Feizabadi MM, Falsafi S, et al. Bifidobacterium bifidumRoseburia intestinalis PubMed ↗
Cellular oncology · 2025 Mendelian analysis reveals novel pancreatic cancer-associated gut bacteria with tumor-suppressive effects. Tong Y, Li Q, Zhang W, et al. Eggerthella lentaParasutterella excrementihominis PubMed ↗
Biomolecules · 2025 Role of Oral Bacteria in Mediating Gemcitabine Resistance in Pancreatic Cancer. Xu G, Jiang Y, Sun C, et al. Enterococcus faecalis PubMed ↗
Frontiers in cellular and infection microbiology · 2025 Microbiological colonization of the pancreatic tumor affects postoperative complications and outcome after pancreatic surgery. Biesel EA, Sundheimer J, Badr MT, et al. Enterococcus faecalisEnterococcus faecium PubMed ↗
Medicina · 2025 Gut Microbiota-Based Immunotherapy: Engineered Escherichia coli Nissle 1917 for Oral Delivery of Glypican-1 in Pancreatic Cancer. Vruzhaj I, Gambirasi M, Busato D, et al. Escherichia coli PubMed ↗
Frontiers in immunology · 2024 Succession of the multi-site microbiome along pancreatic ductal adenocarcinoma tumorigenesis. Zhu Y, Liang X, Zhi M, et al. Bifidobacterium breve PubMed ↗
Gut microbes · 2024 A powerful machine learning approach to identify interactions of differentially abundant gut microbial subsets in patients with metastatic and non-metastatic pancreatic cancer. Villani A, Fontana A, Panebianco C, et al. Anaerostipes hadrusRoseburia inulinivorans PubMed ↗
PloS one · 2024 Microbial profile in bile from pancreatic and extra-pancreatic biliary tract cancer. Di Carlo P, Serra N, Fasciana TMA, et al. Klebsiella pneumoniae PubMed ↗
Frontiers in immunology · 2023 B cell immune profiles in dysbiotic vermiform appendixes of pancreatic cancer patients. Vietsch EE, Latifi D, Verheij M, et al. Adlercreutzia equolifaciensBifidobacterium animalisKlebsiella pneumoniae PubMed ↗
Gastroenterology · 2022 Metagenomic Identification of Microbial Signatures Predicting Pancreatic Cancer From a Multinational Study. Nagata N, Nishijima S, Kojima Y, et al. Faecalibacterium prausnitzii PubMed ↗
Frontiers in cellular and infection microbiology · 2021 Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study. Genton L, Lazarevic V, Stojanovic O, et al. [Clostridium] scindensAlistipes communisEnterocloster bolteaePhascolarctobacterium faecium PubMed ↗
Applied microbiology and biotechnology · 2021 Metagenomic analysis of gut microbiome reveals a dynamic change in Alistipes onderdonkii in the preclinical model of pancreatic cancer, suppressing its proliferation. Lee K, Oh HJ, Kang MS, et al. Alistipes onderdonkiiRoseburia hominis PubMed ↗
The British journal of surgery · 2021 Influence of Klebsiella pneumoniae and quinolone treatment on prognosis in patients with pancreatic cancer. Weniger M, Hank T, Qadan M, et al. Klebsiella pneumoniae PubMed ↗
Journal of translational medicine · 2021 The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing. Zhou W, Zhang D, Li Z, et al. Agathobacter rectalisFaecalibacterium prausnitziiOdoribacter splanchnicusRoseburia intestinalis PubMed ↗
Animal study Journal of controlled release · 2025 Gut microbial diversity is preserved through localised chemo-immunotherapy delivery in a KPC mouse model of pancreatic cancer. Minaei E, Joyce P, Wade SJ, et al. Akkermansia muciniphilaBifidobacterium longum PubMed ↗
Surgery · 2020 Effect of bacterial contamination in bile on pancreatic cancer cell survival. Shrader HR, Miller AM, Tomanek-Chalkley A, et al. Enterococcus faecalis PubMed ↗
BioMed research international · 2020 Novel Discoveries Targeting Pathogenic Gut Microbes and New Therapies in Pancreatic Cancer: Does Pathogenic E. coli Infection Cause Pancreatic Cancer Progression Modulated by TUBB/Rho/ROCK Signaling Pathway? A Bioinformatic Analysis. Luo W, Cao Z, Qiu J, et al. Escherichia coli PubMed ↗
Cancer chemotherapy and pharmacology · 2018 Influence of gemcitabine chemotherapy on the microbiota of pancreatic cancer xenografted mice. Panebianco C, Adamberg K, Jaagura M, et al. Akkermansia muciniphila PubMed ↗