Review The lancet. Gastroenterology & hepatology · 2026 Rifaximin in cirrhosis: when therapeutic drift meets antimicrobial stewardship. Jalan R, Patel VC, Shoaie S Enterococcus faecium PubMed ↗
Observational Journal of gastroenterology and hepatology · 2026 Gut Microbiome Signatures Differ in Cirrhosis With and Without Hepatocellular Carcinoma in a Southeast Asian Cohort. Jinato T, Sikaroodia M, Gilleveta PM, et al. Mediterraneibacter gnavus PubMed ↗
Randomized trial Canadian journal of gastroenterology & hepatology · 2026 Rifaximin Plus Probiotics Reshape Gut Microbiota, Serum Propionate, and Mucosal Immunity in Cirrhosis-Related Hepatic Encephalopathy Microbiota-Immune Remodeling in HE. Wang Y, Zhu H, Wang S, et al. Bacteroides ovatusLigilactobacillus salivarius PubMed ↗
Randomized trial Liver international · 2025 A Metagenomics Approach to Frailty in Patients With Cirrhosis Undergoing a Multifactorial Intervention. Vega-Abellaneda S, Román E, Soler Z, et al. Akkermansia muciniphilaStreptococcus thermophilus PubMed ↗
Observational Clinical and translational gastroenterology · 2025 Fecal Microbiota and Bile Acid Profiles in Early-Stage Hepatocellular Carcinoma: A Matched Case-Control Study. Nobel YR, Park H, Tillman AM, et al. Klebsiella pneumoniae PubMed ↗
Observational mSphere · 2025 Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses. Majernik SN, Beaver L, Bradley PH Lachnospira eligens PubMed ↗
Randomized trial Clinical nutrition ESPEN · 2024 Probiotics may be useful for drug-induced liver dysfunction in patients with depression - A secondary analysis of a randomized clinical trial. Gawlik-Kotelnicka O, Burzyński J, Rogalski J, et al. Bifidobacterium longum PubMed ↗
Observational Clinical and molecular hepatology · 2024 Gut microbiome and metabolome signatures in liver cirrhosis-related complications. Sharma SP, Gupta H, Kwon GH, et al. [Clostridium] symbiosumBacteroides ovatusMediterraneibacter gnavus PubMed ↗
Review Journal of gastroenterology · 2024 Gut microbiota and metabolites of cirrhotic portal hypertension: a novel target on the therapeutic regulation. Hao Y, Hao Z, Zeng X, et al. Alistipes putredinisRoseburia faecisVeillonella dispar PubMed ↗
Randomized trial The Journal of nutrition · 2023 Probiotic Supplementation, Hepatic Fibrosis, and the Microbiota Profile in Patients with Nonalcoholic Steatohepatitis: A Randomized Controlled Trial. Escouto GS, Port GZ, Tovo CV, et al. Bifidobacterium animalis PubMed ↗
Review Frontiers of medicine · 2022 Role of Akkermansia muciniphila in the development of nonalcoholic fatty liver disease: current knowledge and perspectives. Han Y, Li L, Wang B Akkermansia muciniphila PubMed ↗
Observational AIDS · 2022 A pilot study of microbial signatures of liver disease in those with HIV mono-infection in Rio de Janeiro, Brazil. Yanavich C, Perazzo H, Li F, et al. Agathobacter rectalisAkkermansia muciniphilaBacteroides fragilisBacteroides stercoris +5 more PubMed ↗
Randomized trial Journal of hepatology · 2021 Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial. Patel VC, Lee S, McPhail MJW, et al. Veillonella atypica PubMed ↗
Nature communications · 2026 Pharmabiotics, Phocaeicola dorei, ameliorates cholestatic liver fibrosis by alleviating macrophage efferocytosis of neutrophils. Eom JA, Park IG, Hyun JY, et al. Phocaeicola dorei PubMed ↗
Pathogens · 2026 Novel Insights on Clinical Outcomes Using Integrated Shotgun Metagenomic Profiling of the Gut Microbiome, Resistome, and Host Immune-Inflammatory Response in Hospitalized Patients with Decompensated Cirrhosis. Philips CA, Oommen TT, Theruvath AH, et al. Ligilactobacillus salivarius PubMed ↗
Nature microbiology · 2025 Microbial collagenase activity is linked to oral-gut translocation in advanced chronic liver disease. Jin S, Cenier A, Wetzel D, et al. Veillonella parvula PubMed ↗
Liver transplantation · 2025 Baseline oral microbiome associated with post-living donor liver transplant early complications within 6 months. Babu R, Kaur M, Sharma S, et al. Klebsiella pneumoniae PubMed ↗
Clinical laboratory · 2025 Ruminococcus Gnavus Infection Detected in Ascites Fluid in a Patient with Cirrhosis. Xie Y, Wang X, Yan X, et al. Mediterraneibacter gnavus PubMed ↗
Acta microbiologica et immunologica Hungarica · 2025 Changes in intestinal microbiota and abnormal amino acid metabolism lead to neurotransmitter disorders in patients with liver cirrhosis. Gao X, Zhou K, Li S Escherichia coli PubMed ↗
Life sciences · 2025 Phocaeicola plebeius oral treatment improve fibrosis by reversing cirrhosis-related hepatic gene dysregulation. Sharma SP, Cha MG, Kwon GH, et al. Phocaeicola plebeius PubMed ↗
Journal of translational medicine · 2025 Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients. Li S, Xu Z, Diao H, et al. Phocaeicola vulgatus PubMed ↗
Nutrients · 2025 The Association Between Prevotella copri and Advanced Fibrosis in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease. Zhang D, Leitman M, Pawar S, et al. Segatella copri PubMed ↗
Journal of medical microbiology · 2025 Comprehensive toolkit integrating lifestyle and clinical questionnaires with gut microbiota profiling via rectal swabs: application in intensive care cirrhotic patients. Marin J, Ghalayini M, Kaoudji Y, et al. Escherichia coli PubMed ↗
Acta pharmacologica Sinica · 2025 Peptidoglycan isolated from the fruit of Lycium barbarum alleviates liver fibrosis in mice by regulating the TGF-β/Smad7 signaling and gut microbiota. Nie YM, Zhou WQ, Niu T, et al. Akkermansia muciniphila PubMed ↗
Nature medicine · 2025 The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis. He X, Hu M, Xu Y, et al. Mediterraneibacter gnavus PubMed ↗
Advanced science · 2024 Clostridium Scindens Protects Against Vancomycin-Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR-FGF15/19 Signaling. Xiao J, Hou Y, Luo X, et al. [Clostridium] scindens PubMed ↗
Microbiome · 2024 Akkermansia muciniphila improve cognitive dysfunction by regulating BDNF and serotonin pathway in gut-liver-brain axis. Kang EJ, Cha MG, Kwon GH, et al. Akkermansia muciniphila PubMed ↗
Cellular and molecular life sciences · 2024 Splenectomy ameliorates liver cirrhosis by restoring the gut microbiota balance. Jin Y, Shi M, Feng J, et al. Veillonella parvula PubMed ↗
Microbiology spectrum · 2023 Systemic multiomics evaluation of the therapeutic effect of Bacteroides species on liver cirrhosis in male mice. Park YR, Lee HL, Hyun JY, et al. Phocaeicola dorei PubMed ↗
Journal of cachexia, sarcopenia and muscle · 2023 Altered gut microbiome, bile acid composition and metabolome in sarcopenia in liver cirrhosis. Aliwa B, Horvath A, Traub J, et al. Bacteroides fragilisBacteroides ovatusVeillonella parvula PubMed ↗
Frontiers in cellular and infection microbiology · 2023 Integrated microbiome and metabolome analysis reveals the interaction between intestinal flora and serum metabolites as potential biomarkers in hepatocellular carcinoma patients. Li X, Yi Y, Wu T, et al. Odoribacter splanchnicus PubMed ↗
Hepatobiliary & pancreatic diseases international · 2023 Fecal cytolysin does not predict disease severity in acutely decompensated cirrhosis and acute-on-chronic liver failure. Hartmann P, Lang S, Schierwagen R, et al. Enterococcus faecalis PubMed ↗
Nature microbiology · 2022 Longitudinal multi-omics analyses of the gut-liver axis reveals metabolic dysregulation in hepatitis C infection and cirrhosis. Ali RO, Quinn GM, Umarova R, et al. Anaerostipes hadrusPhocaeicola vulgatus PubMed ↗
Gut · 2022 Longitudinal transkingdom gut microbial approach towards decompensation in outpatients with cirrhosis. Bajaj JS, Peña-Rodriguez M, La Reau A, et al. Anaerobutyricum halliiStreptococcus parasanguinis PubMed ↗
Frontiers in cellular and infection microbiology · 2022 Alterations of gut microbiota in cirrhotic patients with spontaneous bacterial peritonitis: A distinctive diagnostic feature. Zhou Z, Lv H, Lv J, et al. Faecalibacterium prausnitziiKlebsiella pneumoniaeRuminococcus callidus PubMed ↗
Medicine · 2022 Changes in intestinal microbiota of HBV-associated liver cirrhosis with/without hepatic encephalopathy. Hua X, Feng H Veillonella parvula PubMed ↗
Journal of gastroenterology · 2022 Pathogenic effects of Desulfovibrio in the gut on fatty liver in diet-induced obese mice and children with obesity. Lin YC, Lin HF, Wu CC, et al. Bifidobacterium animalis PubMed ↗
Expert review of gastroenterology & hepatology · 2022 Altered gut microbiota is associated with sleep disturbances in patients with minimal hepatic encephalopathy caused by hepatitis B-related liver cirrhosis. Luo M, Hu FR, Xin RJ, et al. Streptococcus salivarius PubMed ↗
Hepatology · 2022 Impact of bacterial infections and spontaneous bacterial peritonitis prophylaxis on phage-bacterial dynamics in cirrhosis. Bajaj JS, Rodriguez MP, Fagan A, et al. Enterococcus faecium PubMed ↗
Hepatology communications · 2022 Distinct responsiveness to rifaximin in patients with hepatic encephalopathy depends on functional gut microbial species. Yukawa-Muto Y, Kamiya T, Fujii H, et al. Mediterraneibacter gnavusStreptococcus salivarius PubMed ↗