Systematic review International journal of molecular sciences · 2026 Gut, Oral, and Fungal Microbiota in Hypertension: A Multi-Compartment Systematic Review. Carini F, Sorce A, Ciuppa ME, et al. Mediterraneibacter gnavus PubMed ↗
Review Medicina · 2026 Gut Microbiota in Metabolic Syndrome: Differences in Microbial Signatures and Clinical Profiles. Scarlata GGM, Belančić A, Scarpellini E, et al. Akkermansia muciniphila PubMed ↗
Observational BMC microbiology · 2026 A validation for sex differences in gut microbiome of essential hypertension based on cohort analysis. Wang P, Yao Y, Yan K, et al. Mediterraneibacter gnavus PubMed ↗
Review Clinical and experimental hypertension · 2025 Gut microbiota and hypertension: role of exercise training. Zhao M, Liu Q, Shi NJ, et al. Faecalibacterium prausnitzii PubMed ↗
Observational American journal of physiology. Heart and circulatory physiology · 2025 Altered tryptophan metabolism and gut immune crosstalk in hypertensive middle-aged women. Shah S, Mu C, Shen-Tu G, et al. Alistipes shahiiBacteroides stercoris PubMed ↗
Observational mSystems · 2025 Cross-cohort microbiome-wide study reveals consistent alterations in the gut bacteriome, but not the gut mycobiome, in patients with hypertension. Gao Y, Wang D, Lu T, et al. [Clostridium] symbiosumEnterocloster bolteae PubMed ↗
Randomized trial Microbiome · 2025 Fecal microbiota transplantation for hypertension: an exploratory, multicenter, randomized, blinded, placebo-controlled trial. Fan L, Chen J, Zhang Q, et al. Anaerostipes hadrusCoprococcus catusEggerthella lentaParabacteroides merdae +2 more PubMed ↗
Review Journal of translational medicine · 2025 The differences in intestinal flora and metabolites between H-type hypertension and non-H-type hypertension. Wu J, Zhao J, Cheng Y, et al. Bacteroides stercorisPhocaeicola plebeiusPhocaeicola vulgatus PubMed ↗
Observational Journal of clinical hypertension · 2024 Causal Associations Between the Gut Microbiota and Hypertension-Related Traits Through Mendelian Randomization: A Cross-Sectional Cohort Study. Tian Y, Gu M, Chen D, et al. [Clostridium] innocuumFaecalicatena fissicatena PubMed ↗
Observational Journal of the American Heart Association · 2024 Disordered Gut Microbiome and Alterations in Metabolic Patterns Are Associated With Hypertensive Left Ventricular Hypertrophy. Cao R, Gao T, Yue J, et al. [Ruminococcus] torques PubMed ↗
Randomized trial PeerJ · 2024 Microbiota based personalized nutrition improves hyperglycaemia and hypertension parameters and reduces inflammation: a prospective, open label, controlled, randomized, comparative, proof of concept study. Kallapura G, Prakash AS, Sankaran K, et al. Alistipes finegoldii PubMed ↗
Randomized trial Probiotics and antimicrobial proteins · 2024 Effects of Probiotics on Inflammatory Biomarkers and Its Associations With Cardiac Autonomic Function in Women With Arterial Hypertension: A Secondary Analysis of a Randomized Clinical Trial. Maia LA, de Souza JR, da Silva LFR, et al. Bifidobacterium animalis PubMed ↗
Observational Hypertension · 2023 Sex Differences in Association Between Gut Microbiome and Essential Hypertension Based on Ambulatory Blood Pressure Monitoring. Virwani PD, Qian G, Hsu MSS, et al. Bacteroides ovatusDorea formicigeneransEnterocloster bolteaeMediterraneibacter gnavus PubMed ↗
Meta-analysis Hypertension · 2022 Causality of Opportunistic Pathogen Klebsiella pneumoniae to Hypertension Development. Li J, Gao Q, Ma Y, et al. Klebsiella pneumoniae PubMed ↗
Review Journal of translational medicine · 2022 The potential impact of a probiotic: Akkermansia muciniphila in the regulation of blood pressure-the current facts and evidence. Lakshmanan AP, Murugesan S, Al Khodor S, et al. Akkermansia muciniphila PubMed ↗
Observational Journal of Alzheimer's disease · 2021 The Alzheimer-E. coli Axis: What Can We Learn from an Electronic Health Record Platform. Katz J, Gao H Escherichia coli PubMed ↗
Nutrients · 2026 Bifidobacterium Mediates the Associations Between the Dietary Approaches to Stop Hypertension (DASH) Diet and Blood Pressure and Blood Lipids in Chinese Adults. Zhang Q, Zhang Y, Ren M, et al. Bifidobacterium longum PubMed ↗
Pharmacological research · 2025 Intermittent fasting ameliorates resistant hypertension through modulation of gut microbiota. Yun F, Han X, Wang Z, et al. Adlercreutzia equolifaciensAkkermansia muciniphila PubMed ↗
Gene · 2024 Genetic association between gut microbiome and blood pressure and blood cell count as mediator: A two-step Mendelian randomization analysis. Zhang J, He J, Liao Y, et al. Eubacterium ventriosum PubMed ↗
Frontiers in cellular and infection microbiology · 2024 Oral-to-rectum microbial transmission in orthopedic patients without a history of intestinal disorders. Lin G, Kageyama S, Maeda A, et al. Alistipes finegoldiiKlebsiella pneumoniaeStreptococcus parasanguinisStreptococcus salivarius PubMed ↗
Nutrients · 2023 Effect of Lactobacillus kefiri, in Conjunction with PENS T6 and a Hypocaloric Diet, on Weight Loss, Hypertension and Laboratory Glycemic and Lipid Profile. Ruiz-Tovar J, Llavero C, Fernandez-Contreras ME Akkermansia muciniphila PubMed ↗
mSystems · 2023 Probiotics Bifidobacterium lactis M8 and Lactobacillus rhamnosus M9 prevent high blood pressure via modulating the gut microbiota composition and host metabolic products. Zhang Y, Zheng T, Ma D, et al. Bifidobacterium animalis PubMed ↗
BMC microbiology · 2023 Gut microbiome profile of Chinese hypertension patients with and without type 2 diabetes mellitus. Ding H, Xu Y, Cheng Y, et al. Alistipes onderdonkiiAlistipes putredinisBacteroides uniformisBlautia wexlerae +4 more PubMed ↗
The Journal of nutrition · 2022 Tea Consumption and Gut Microbiome in Older Chinese Adults. Wang L, Shu XO, Cai H, et al. Collinsella aerofaciensCoprococcus catusDorea formicigenerans PubMed ↗
Circulation research · 2022 Gut Dysbiosis Promotes Preeclampsia by Regulating Macrophages and Trophoblasts. Jin J, Gao L, Zou X, et al. Akkermansia muciniphila PubMed ↗
Frontiers in cellular and infection microbiology · 2022 The P4 Study: Postpartum Maternal and Infant Faecal Microbiome 6 Months After Hypertensive Versus Normotensive Pregnancy. Susic DF, Wang L, Roberts LM, et al. Barnesiella intestinihominisEnterocloster aldenensis PubMed ↗
Georgian medical news · 2022 QUANTITATIVE CHARACTERISTICS OF GUT MICROBIOTA IN PATIENTS WITH ARTERIAL HYPERTENSION. Koval S, Snihurska I, Yushko K, et al. Faecalibacterium prausnitzii PubMed ↗
American heart journal · 2021 Depressive hypertension: A proposed human endotype of brain/gut microbiome dysbiosis. Stevens BR, Pepine CJ, Richards EM, et al. [Eubacterium] siraeumAlistipes communisHoldemania filiformis PubMed ↗
Journal of human hypertension · 2021 Profile of gut flora in hypertensive patients with insufficient sleep duration. Jiao J, Dong Y, Wang P, et al. Roseburia inulinivorans PubMed ↗
Acta diabetologica · 2021 Fecal microbiota signatures of insulin resistance, inflammation, and metabolic syndrome in youth with obesity: a pilot study. Del Chierico F, Manco M, Gardini S, et al. Bacteroides caccaeBacteroides ovatusFaecalibacterium prausnitziiHaemophilus parainfluenzae PubMed ↗
Animal study International journal of molecular sciences · 2026 Vine Tea (Ampelopsis grossedentata) Extract Mitigates High-Salt-Diet-Induced Hypertension by Remodeling the Gut Microbiota-Metabolite Axis in Mice. Gu Y, Li Q, Cao L, et al. [Ruminococcus] torques PubMed ↗
Animal study Food & function · 2025 Antihypertensive effects of rice peptides involve intestinal microbiome alterations and intestinal inflammation alleviation in spontaneously hypertensive rats. Li J, Wei W, Ma X, et al. Lactococcus lactis PubMed ↗
Animal study Scientific reports · 2024 Differential gene expression in the kidneys of SHR and WKY rats after intravenous administration of Akkermansia muciniphila-derived extracellular vesicles. Olarinoye ZY, Kim CW, Kim JY, et al. Akkermansia muciniphila PubMed ↗
Animal study Hypertension research · 2024 Akkermansia muciniphila extracellular vesicles have a protective effect against hypertension. Kim JY, Kim CW, Oh SY, et al. Akkermansia muciniphila PubMed ↗
Animal study Journal of dairy science · 2023 The therapeutic effects of fermented milk with lactic acid bacteria from traditional Daqu on hypertensive mice. Jiang Y, Wu J, Tian L, et al. Enterococcus faecium PubMed ↗
Animal study International journal of molecular sciences · 2023 Clostridium butyricum Prevents Dysbiosis and the Rise in Blood Pressure in Spontaneously Hypertensive Rats. Luo X, Han Z, Kong Q, et al. Akkermansia muciniphila PubMed ↗
Animal study Food & function · 2022 Bifidobacterium longum CCFM752 prevented hypertension and aortic lesion, improved antioxidative ability, and regulated the gut microbiome in spontaneously hypertensive rats. Lu W, Wang Y, Fang Z, et al. Bifidobacterium longum PubMed ↗
Animal study mSystems · 2022 Multi-omic Profiling Reveals that Intra-abdominal-Hypertension-Induced Intestinal Damage Can Be Prevented by Microbiome and Metabolic Modulations with 5-Hydroxyindoleacetic Acid as a Diagnostic Marker. Li F, Jiang L, Pan S, et al. Bacteroides eggerthiiBacteroides fragilisBacteroides ovatusFaecalibacterium prausnitzii PubMed ↗
Animal study Gut microbes · 2022 Kidney microbiota dysbiosis contributes to the development of hypertension. Liu XY, Li J, Zhang Y, et al. Klebsiella pneumoniae PubMed ↗
Animal study Nutrients · 2021 Probiotics Prevent Hypertension in a Murine Model of Systemic Lupus Erythematosus Induced by Toll-Like Receptor 7 Activation. de la Visitación N, Robles-Vera I, Moleón-Moya J, et al. Bifidobacterium breve PubMed ↗