Observational International journal of rheumatic diseases · 2026 Integrated Analysis of Gut Microbiota and Fecal Metabolites in Chinese Patients With Rheumatoid Arthritis: Associations With Disease Activity. Liang J, Wei X, Shang C, et al. Bifidobacterium adolescentis PubMed ↗
Systematic review The Journal of rheumatology · 2026 Gut Microbiota as a Biomarker and Target in Biologic Therapy for Autoimmune and Immune-Mediated Arthritis: A Systematic Review. Rondla M, Zaazouee MS, Perumangote Vasudevan AA, et al. Faecalibacterium prausnitzii PubMed ↗
Review Frontiers in immunology · 2026 Mechanistic insights into gut microbiota-driven autoimmunity in rheumatoid arthritis. Li J, Chen X, Xie X Segatella copri PubMed ↗
Randomized trial Journal of infection in developing countries · 2025 Therapeutical efficacy of immunobiotics in patients with newly diagnosed rheumatoid arthritis. Barac B, Lukovic S, Kojic T, et al. Bifidobacterium breveLigilactobacillus salivarius PubMed ↗
Review The Journal of clinical investigation · 2025 Microbial threads in the tapestry of rheumatoid arthritis. Li J, Kuhn KA Eggerthella lentaSegatella copri PubMed ↗
Review Autoimmunity reviews · 2025 Gut microbiota in rheumatoid arthritis: Mechanistic insights, clinical biomarkers, and translational perspectives. Qi XY, Liu MX, Jiang XJ, et al. Mediterraneibacter gnavusSegatella copri PubMed ↗
Review Clinical and experimental medicine · 2025 Immunomodulatory properties of the gut microbiome: diagnostic and therapeutic potential for rheumatoid arthritis. Abebaw D, Akelew Y, Adugna A, et al. Segatella copri PubMed ↗
Review Clinical and experimental rheumatology · 2025 Research trends and hotspots on gut microbiota in rheumatoid arthritis: a bibliometric analysis from 2004 to 2024. Zheng Z, Liu X, Zhang Y, et al. Segatella copri PubMed ↗
Review International journal of rheumatic diseases · 2025 Impact of Gut Microbiota and Probiotics on Rheumatoid Arthritis: A Potential Treatment Challenge. Ajith TA, Anita B Agathobacter rectalisSegatella copri PubMed ↗
Review International journal of molecular sciences · 2024 Infectious and Commensal Bacteria in Rheumatoid Arthritis-Role in the Outset and Progression of the Disease. Korzeniowska A, Bryl E Segatella copri PubMed ↗
Review International journal of rheumatic diseases · 2024 The role of microbiota on rheumatoid arthritis onset. Juárez-Chairez MF, Cid-Gallegos MS, Jiménez-Martínez C, et al. Ligilactobacillus salivariusSegatella copri PubMed ↗
Observational International journal of molecular sciences · 2023 Serum Levels of IFABP2 and Differences in Lactobacillus and Porphyromonas gingivalis Abundance on Gut Microbiota Are Associated with Poor Therapeutic Response in Rheumatoid Arthritis: A Pilot Study. Zaragoza-García O, Castro-Alarcón N, Pérez-Rubio G, et al. Bacteroides fragilis PubMed ↗
Review Joint bone spine · 2022 Contribution of HLA DRB1, PTPN22, and CTLA4, to RA dysbiosis. Berthelot JM, Darrieutort-Laffite C, Le Goff B Faecalibacterium prausnitziiSegatella copri PubMed ↗
Observational Frontiers in immunology · 2021 Therapeutic Potential of a Novel Bifidobacterium Identified Through Microbiome Profiling of RA Patients With Different RF Levels. Jeong Y, Jhun J, Lee SY, et al. Bifidobacterium longum PubMed ↗
Review Probiotics and antimicrobial proteins · 2021 Interplay of Microbiota and Citrullination in the Immunopathogenesis of Rheumatoid Arthritis. Alghamdi MA, Redwan EM Segatella copri PubMed ↗
Randomized trial Nutrition · 2021 Mixture of probiotics reduces inflammatory biomarkers and improves the oxidative/nitrosative profile in people with rheumatoid arthritis. Cannarella LAT, Mari NL, Alcântara CC, et al. Bifidobacterium animalisLactococcus lactis PubMed ↗
Molecular nutrition & food research · 2026 Heat-Killed Bifidobacterium longum ZFML0012 Alleviates Rheumatoid Arthritis via Gut-Joint Axis Regulation: Remodeling Microbiota, Boosting SCFAs/L-Glutamine, and Rebalancing Th17/Treg Immunity. Yang T, Zhang Y, Huang Y, et al. Bifidobacterium longum PubMed ↗
Medicine · 2026 Causal relationship between gut microbiota and rheumatoid arthritis: A bidirectional 2-sample Mendelian randomization study. Zhang S, Li Y, Cheng H, et al. Alistipes shahiiBifidobacterium breveLactococcus lactis PubMed ↗
Gut · 2026 Pueraria lobata-derived exosome-like nanovesicles alleviate rheumatoid arthritis via targeting Ruminococcus gnavus phenylethylamine production. Han B, Jiang Y, Liu H, et al. Mediterraneibacter gnavus PubMed ↗
Cell reports · 2026 Mucosal innate immune activation as the trigger to Prevotella species-induced arthritis in genetically resistant mice. Maeda Y, Rabenow M, Xiang W, et al. Segatella copri PubMed ↗
Annals of the rheumatic diseases · 2025 Short-chain fatty acids and their gut microbial pathways distinguish rheumatoid arthritis in discordant monozygotic twins. Blank RB, Bu K, Zhang X, et al. Blautia faecisFaecalicatena fissicatenaGemmiger formicilis PubMed ↗
Frontiers in immunology · 2025 From gut to joint: the protective impact of Eubacterium rectale on rheumatoid arthritis. Liu X, Wu R, Fan Y, et al. Agathobacter rectalis PubMed ↗
Cell metabolism · 2024 Dietary-timing-induced gut microbiota diurnal oscillations modulate inflammatory rhythms in rheumatoid arthritis. Ma F, Li Z, Liu H, et al. Parabacteroides distasonis PubMed ↗
Journal of medical virology · 2024 Multikingdom characterization of gut microbiota in patients with rheumatoid arthritis and rheumatoid arthritis-associated interstitial lung disease. Xing Y, Liu Y, Sha S, et al. Bifidobacterium longumCollinsella aerofaciensDorea formicigeneransFaecalibacterium prausnitzii +4 more PubMed ↗
Scientific reports · 2023 CXCL10 as a shared specific marker in rheumatoid arthritis and inflammatory bowel disease and a clue involved in the mechanism of intestinal flora in rheumatoid arthritis. Guan Y, Zhang Y, Zhu Y, et al. Ruminococcus bromii PubMed ↗
Cellular & molecular immunology · 2022 A high-fiber diet synergizes with Prevotella copri and exacerbates rheumatoid arthritis. Jiang L, Shang M, Yu S, et al. Segatella copri PubMed ↗
Microbiology spectrum · 2022 Dysbiotic Oral and Gut Viromes in Untreated and Treated Rheumatoid Arthritis Patients. Guo R, Li S, Zhang Y, et al. Lactococcus lactisPhocaeicola vulgatus PubMed ↗
BMC oral health · 2021 Subgingival microbiome of deep and shallow periodontal sites in patients with rheumatoid arthritis: a pilot study. Lehenaff R, Tamashiro R, Nascimento MM, et al. Streptococcus parasanguinis PubMed ↗
Immunology letters · 2021 Protective effect of Bacteroides fragilis LPS on Escherichia coli LPS-induced inflammatory changes in human monocytic cells and in a rheumatoid arthritis mouse model. Kitamura K, Sasaki M, Matsumoto M, et al. Bacteroides fragilis PubMed ↗
Rheumatology · 2021 Influence of proton pump inhibitor or rebamipide use on gut microbiota of rheumatoid arthritis patients. Kim JW, Jeong Y, Park SJ, et al. Enterocloster bolteae PubMed ↗
Animal study Frontiers in immunology · 2026 The alterations in the gut microbiota and Bifidobacterium animalis BD400 during the development and progression of collagen-induced arthritis in rats. Yang Y, Hong Q, Liu Z Bifidobacterium animalis PubMed ↗
Animal study Journal of ethnopharmacology · 2025 Total flavonoids of Drynaria fortunei ameliorates rheumatoid arthritis by suppressing P. copri-mediated Th17 cell differentiation. Liang H, Li C, Wang Y, et al. Segatella copri PubMed ↗
Animal study Food & function · 2025 Lactiplantibacillus plantarum fermented hemp (Cannabis sativa) seeds modulate the gut microbiota and metabolic pathways to alleviate autoimmune inflammation in collagen-induced arthritis mice. Shan L, Chelliah R, Park S, et al. Akkermansia muciniphilaPhocaeicola vulgatus PubMed ↗
Animal study PloS one · 2025 Comprehensive safety assessment and therapeutic potential of Pediococcus acidilactici NMCC-B in attenuating arthritis progression. Zulfiqar T, Tipu MK, Khan MT, et al. Escherichia coli PubMed ↗
Animal study Frontiers in immunology · 2025 Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism. Yang Y, Hong Q, Zhang X, et al. Bifidobacterium animalis PubMed ↗
Animal study Nutrients · 2023 Gut-Joint Axis: Impact of Bifidobacterial Cell Wall Lipoproteins on Arthritis Development. Piva F, Gervois P, Karrout Y, et al. Bifidobacterium longum PubMed ↗
Animal study Annals of the rheumatic diseases · 2023 Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis. Nii T, Maeda Y, Motooka D, et al. Segatella copri PubMed ↗
Animal study Gut · 2023 Gut commensal Parabacteroides distasonis alleviates inflammatory arthritis. Sun H, Guo Y, Wang H, et al. Parabacteroides distasonis PubMed ↗
Animal study Nutrients · 2023 Bifidobacterium pseudocatenulatum-Mediated Bile Acid Metabolism to Prevent Rheumatoid Arthritis via the Gut-Joint Axis. Zhao Q, Ren H, Yang N, et al. Bifidobacterium pseudocatenulatum PubMed ↗
Observational Annals of the rheumatic diseases · 2020 Circulating microbial small RNAs are altered in patients with rheumatoid arthritis. Ormseth MJ, Wu Q, Zhao S, et al. Ligilactobacillus salivarius PubMed ↗