Observational JAMA network open · 2026 Probiotics and Risk of Death, Necrotizing Enterocolitis, and Sepsis in Very Preterm Infants. Mitha A, Söderquist Kruth S, Sinervo E, et al. Bifidobacterium animalisBifidobacterium longumStreptococcus thermophilus PubMed ↗
Randomized trial Pediatric research · 2025 L.Fermentum CECT5716 and B.Breve CECT7263 on premature infants morbidities: a randomized clinical trial. Hurtado Suazo JA, Alonso Ojembarrena A, Sánchez Tamayo T, et al. Bifidobacterium breve PubMed ↗
Meta-analysis The journal of maternal-fetal & neonatal medicine · 2025 Efficacy of probiotic supplementation in preventing necrotizing enterocolitis in preterm infants: a systematic review and meta-analysis. Abdullahi AM, Zhao S, Xu Y Bifidobacterium bifidum PubMed ↗
Randomized trial Medicine · 2024 Effects of synbiotics on necrotizing enterocolitis and full enteral feeding in very low birth weight infants: A double-blind, randomized controlled trial. Mahboobipour AA, Bitaraf A, Mohammadi P, et al. Bifidobacterium longum PubMed ↗
Meta-analysis Medicine · 2023 Can Enterococcus faecium prevent NEC in preterm infants?: A systematic review and meta-analysis. Men G, Wang L, Lu X, et al. Enterococcus faecium PubMed ↗
Meta-analysis Pediatric research · 2023 Bifidobacterium infantis as a probiotic in preterm infants: a systematic review and meta-analysis. Batta VK, Rao SC, Patole SK Bifidobacterium longum PubMed ↗
Systematic review Nutrients · 2022 The Metabolome and the Gut Microbiota for the Prediction of Necrotizing Enterocolitis and Spontaneous Intestinal Perforation: A Systematic Review. Moschino L, Verlato G, Duci M, et al. Phocaeicola dorei PubMed ↗
Observational Beneficial microbes · 2021 Effectiveness of two probiotics in preventing necrotising enterocolitis in a cohort of very-low-birth-weight premature new-borns. Uberos J, Campos-Martinez A, Fernandez-Marín E, et al. Bifidobacterium bifidum PubMed ↗
Observational Pediatrics and neonatology · 2021 Risk factors for hyperglycemia in extremely low birth weight infants during the first 14 days. Inage Y, Hirano D, Nakagawa A, et al. Bifidobacterium breve PubMed ↗
Systematic review Nutrients · 2021 Probiotics for Preventing Necrotizing Enterocolitis in Preterm Infants: A Network Meta-Analysis. Beghetti I, Panizza D, Lenzi J, et al. Bifidobacterium animalis PubMed ↗
Observational Gut microbes · 2021 The effect of early probiotic exposure on the preterm infant gut microbiome development. Hui Y, Smith B, Mortensen MS, et al. Bifidobacterium animalis PubMed ↗
JAMA network open · 2026 Probiotic Implementation and Necrotizing Enterocolitis Risk in Preterm Infants. Imren C, Jongejans V, Onland W, et al. Bifidobacterium animalisBifidobacterium longumStreptococcus thermophilus PubMed ↗
Cell reports. Medicine · 2026 Gut-microbiota-derived 3-indoleacrylic acid alleviates neonatal necrotizing enterocolitis by inhibiting epithelial necroptosis. Dong X, Wang M, Wang B, et al. Bifidobacterium longum PubMed ↗
The Journal of pediatrics · 2025 Increase in Necrotizing Enterocolitis with Cessation of Bifidobacteriumlongum ssp. infantis Administration in Very Low Birthweight Infants: A Single Center Retrospective Cohort Study. Selesner L, Hedges M, Pung R, et al. Bifidobacterium longum PubMed ↗
Food & function · 2025 From microbiota to metabolomics: how Bifidobacterium infantis YLGB-1496 shields neonates from necrotizing enterocolitis. Li J, Lan H, Liu Y, et al. Bifidobacterium longum PubMed ↗
Scientific reports · 2025 An early post-birth immune-microbiota landscape predicts the development of necrotizing enterocolitis in term newborns with congenital heart defects. Zaikova E, Kaplina A, Belozertsev D, et al. Mediterraneibacter gnavus PubMed ↗
Frontiers in cellular and infection microbiology · 2025 Characterization of gut microbiota signatures in Indian preterm infants with necrotizing enterocolitis: a shotgun metagenomic approach. Devarajalu P, Attri SV, Kumar J, et al. Klebsiella pneumoniae PubMed ↗
Nutrients · 2025 Butyrate Producers in Very Low Birth Weight Infants with Neither Culture-Proven Sepsis nor Necrotizing Enterocolitis. Thatrimontrichai A, Praditaukrit M, Maneenil G, et al. Bacteroides fragilis PubMed ↗
Gut microbes · 2024 Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production. Pan LL, Sun Y, Dong X, et al. Lactobacillus gasseri PubMed ↗
Journal of perinatology · 2024 Bifidobacterium longum subsp infantis (EVC001) is associated with reduced incidence of necrotizing enterocolitis stage ≥2 and bloody stools in premature babies. Sohn K, Palacios V, Clark R Bifidobacterium longum PubMed ↗