Randomized trial European journal of nutrition · 2022 Bifidobacterium lactis Probio-M8 improves bone metabolism in patients with postmenopausal osteoporosis, possibly by modulating the gut microbiota. Zhao F, Guo Z, Kwok LY, et al. Bifidobacterium animalis PubMed ↗
Free radical biology & medicine · 2026 The Metabolite indole-3-acetic acid of Bacteroides ovatus ameliorates ovariectomy-induced bone loss by activating AhR and inhibiting oxidative stress. Cui P, Zhang H, Hu T, et al. Bacteroides ovatus PubMed ↗
Journal of nanobiotechnology · 2026 Engineered Akkermansia muciniphila extracellular vesicles for targeted delivery of miR-21-5p alleviate postmenopausal osteoporosis via PI3K-AKT pathway. Ji N, Zhao J, Mao Y, et al. Akkermansia muciniphila PubMed ↗
Turkish journal of medical sciences · 2026 Comprehensive profiling of gut microbiota in postmenopausal osteoporosis. Ertürk Çelik G, Yildiz S, Aksoy Bektaş M, et al. Faecalibacterium prausnitzii PubMed ↗
Journal of leukocyte biology · 2025 Gut-resident regulatory T cells (GTregs) play a pivotal role in maintaining bone health under postmenopausal osteoporotic conditions. Bhardwaj A, Sapra L, Madan D, et al. Bifidobacterium longum PubMed ↗
Calcified tissue international · 2024 The Characteristics of Gut Microbiota and Its Relation with Diet in Postmenopausal Osteoporosis. Chen T, Meng F, Wang N, et al. Bifidobacterium animalisBifidobacterium breve PubMed ↗
Cell proliferation · 2022 Gut microbiota modulates osteoclast glutathione synthesis and mitochondrial biogenesis in mice subjected to ovariectomy. Yuan Y, Yang J, Zhuge A, et al. Ligilactobacillus salivarius PubMed ↗
Animal study African journal of reproductive health · 2026 Effects of probiotic modulation on bone health in estrogen-deficient female Sprague-Dawley rats. Zhang D, Wang X, Deng T, et al. Bifidobacterium breveBifidobacterium longum PubMed ↗