Randomized trial Clinical oral investigations · 2026 Salivary microbiome responses to chlorhexidine and Coriandrum sativum essential oil mouthwashes in patients with periodontitis in a randomized 2-week clinical trial. Kazarina A, Vaškevica A, Senkāne DE, et al. Porphyromonas PubMed ↗
Review Einstein · 2026 Bacteria-induced immunity: from homeostasis to immune subversion in periodontitis. Miranda VL, Teixeira MA, Souza JGS, et al. Porphyromonas PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Absolute quantification by mouthwash testing screens severe periodontitis and tracks species-specific microbial response to periodontal therapy. Eom JH, Cho MY, Kim JW, et al. FusobacteriumPorphyromonas PubMed ↗
Observational Journal of clinical periodontology · 2026 Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression. Manzoor M, Leskelä J, Könönen E, et al. FusobacteriumPorphyromonas PubMed ↗
Review Journal of cellular and molecular medicine · 2026 From Periodontal Pocket to Systemic Diseases: Mechanistic Insights Into the Role of Porphyromonas gingivalis in Host Pathology. Basalim AA, Lu EM Porphyromonas PubMed ↗
Randomized trial International dental journal · 2026 Short-Term Effects of Comprehensive Periodontal Initial Therapy on Subgingival Microbiota in Nasopharyngeal Carcinoma Patients Undergoing Radiotherapy: A Pilot Randomised Controlled Trial. Lv S, Xu Z, He Q, et al. FusobacteriumHaemophilusPrevotellaVeillonella PubMed ↗
Randomized trial Journal of dentistry · 2026 Cross-kingdom dynamics of the subgingival bacteriome and mycobiome: A pilot study on the effects of a novel HA-H₂O₂-Glycine formulation to treat periodontitis. Gini C, Farronato M, Manunza A, et al. Rothia PubMed ↗
Review Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology · 2026 [Oral-gut axis: the microbial and immune bridge linking periodontitis to inflammatory bowel disease]. Gu ZY, Cao J, Hu WJ, et al. Porphyromonas PubMed ↗
Randomized trial Nature communications · 2026 Oral microbiome modulation mitigates hyperglycemia exacerbation in gestational diabetes mellitus. Gao S, Yin N, Wei R, et al. PorphyromonasPrevotellaStreptococcus PubMed ↗
Observational International dental journal · 2026 Differential Associations of Human Herpesviruses With Oral Bacteria and Periodontitis Severity: A Cross-Sectional Analysis. Zhao M, Zhou J, Yang W, et al. Porphyromonas PubMed ↗
Review Clinical and experimental dental research · 2026 The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis. Afshar Y, Rezaei N FusobacteriumPorphyromonas PubMed ↗
Observational Journal of periodontology · 2026 Association between oral microbial diversity and periodontitis in a nationally representative U.S. population: A cross-sectional study. Pu R, Wang Z, Chen Y, et al. PorphyromonasRothiaVeillonella PubMed ↗
Observational Journal of clinical periodontology · 2026 Stage-Associated Subgingival Dysbiosis Across the Periodontal Disease Spectrum in a Thai Cohort. Sawangpanyangkura T, Suparan K, Wechwithayakhlung C, et al. AllisonellaDialisterOdoribacterPorphyromonas +1 more PubMed ↗
Observational Future microbiology · 2026 Oral microbiome dysbiosis of Porphyromonas gingivalis in oral leukoplakia, oral squamous cell carcinoma and radiation-induced oral mucositis: a qPCR-based cross-sectional study. Verma AK, Narwal A, Kamboj M, et al. Porphyromonas PubMed ↗
Review Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026 [The Oral Microbiome: Maintenance of Homeostasis, Disease Associations, and Mechanisms of Pathogenesis]. Chen Z, Zhang X FusobacteriumPorphyromonasStreptococcus PubMed ↗
Review Frontiers in immunology · 2026 The oral - X axis: from periodontal dysbiosis to systemic disease. Jin W, Tang L, Yang J, et al. FusobacteriumPorphyromonas PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Oral microbiome profiles by periodontitis stage in a Korean population. Cho MY, Eom JH, Kim JW, et al. MegasphaeraRothia PubMed ↗
Review Microbiological research · 2026 Bacterial extracellular vesicles in the oral-gut axis: Roles in periodontitis and inflammatory bowel disease. He J, Hu H, Huang Y, et al. Akkermansia muciniphilaPorphyromonas PubMed ↗
Randomized trial BMC oral health · 2026 Adjunctive effect of gaseous ozone on inflammatory biomarkers and microbial profile in grade C molar-incisor pattern periodontitis: a randomized split-mouth placebo-controlled clinical trial. Cetiner DO, Karaduman B, Selman AE, et al. Porphyromonas PubMed ↗
Review Journal of Alzheimer's disease · 2026 From periodontitis to neurodegeneration: Can probiotics modulate the P. gingivalis-amyloid pathway in Alzheimer's disease? Sharif-Askari Z, Atoui K, El Zein W, et al. Porphyromonas PubMed ↗
Review APMIS · 2026 Mapping the Research Landscape and Evolutionary Trends of the Oral Microbiome in Periodontitis. Wang X, Ma Y, Yang Y, et al. Porphyromonas PubMed ↗
Review Frontiers in immunology · 2026 Red-complex bacteria: immunological background leading to the development of head and neck cancers. Kaźmierczak-Siedlecka K, Kucharski R, Kosiński A, et al. Porphyromonas PubMed ↗
Observational Frontiers in endocrinology · 2026 Salivary microbiota signatures of periodontitis are associated with CGM-derived short-term glycaemic control in adults with type 1 diabetes: a pilot study. Munsch K, Sun J, Canceill T, et al. Eubacterium PubMed ↗
Systematic review BMC oral health · 2026 Clinical efficacy of Lactobacillus plantarum and Lactobacillus brevis as adjuncts to professional mechanical plaque removal in periodontitis: a systematic review. Putri RRGA, Sulijaya B, Soeroso Y, et al. Lactiplantibacillus plantarumLevilactobacillus brevis PubMed ↗
Observational Journal of applied microbiology · 2026 Integrative analysis of bacterial diversity in patients with type 2 diabetes mellitus and periodontitis using a case-control microbiome approach. Martínez-Gregorio H, Vallejo-Lecuona F, Ambriz-Barrera F, et al. GemellaHaemophilusMegasphaera PubMed ↗
Randomized trial BMC oral health · 2026 Oral probiotic Weissella cibaria improves halitosis and reduces periodontal pathogens: a randomized, double-blind, placebo-controlled trial. Lee SK, Lim KO, Yang KI, et al. Porphyromonas PubMed ↗
Observational Scientific reports · 2026 Potential biomarkers for early periodontal inflammation: investigating CD5+ B cells, salivary cytokines and oral microbiome. Gottschalk EC, Chabanovska O, Vasudevan P, et al. Megasphaera PubMed ↗
Observational Journal of periodontal research · 2026 Molar-Incisor and Generalized Grade C Periodontitis: Distinct Microbiome-Immune Interactions Suggest Divergent Pathogenesis. Stolf CS, Paz HES, Paraluppi MC, et al. Porphyromonas PubMed ↗
Review Frontiers in immunology · 2026 Immunomodulatory effects of oral microbiota in the pathogenesis of rheumatoid arthritis. Yang Y, Wang G, Song Y, et al. Porphyromonas PubMed ↗
Observational BMC oral health · 2026 Periodontal disease-associated oral and gut microbiome changes in female rheumatoid arthritis patients. Wang X, Long T, Shen L, et al. FusobacteriumPorphyromonasPrevotellaStreptococcus PubMed ↗
Observational Scientific reports · 2026 Culturable and unculturable periodontal microorganisms in non-small cell lung cancer: an exploratory analysis. Chamat M, Lafaurie GI, Castillo DM, et al. EubacteriumPorphyromonas PubMed ↗
Review Wiadomosci lekarskie · 2026 Periodontitis as a systemic inflammatory disorder - implications for cardiovascular and neurodegenerative diseases. Sobiech L, Wójcik L, Jankowska N, et al. Porphyromonas PubMed ↗
Review CNS neuroscience & therapeutics · 2026 The Interface of Oral and Brain Health: Current Insights Into the Bidirectional Relationship Between Alzheimer's Disease and Periodontitis. Zhang W, Li S, Cui Y, et al. Porphyromonas PubMed ↗
Observational BMC oral health · 2025 Comparative analysis of the microbiota in gingival crevicular fluid from peri-implantitis and periodontitis using 16 S ribosomal RNA gene amplicon sequencing: a cross-sectional study. Liu H, Chen J, Chen Q, et al. FusobacteriumHaemophilusPrevotellaVeillonella PubMed ↗
Randomized trial Clinical oral investigations · 2025 Three-session non-surgical therapy stabilizes microbiological and biochemical responses in patients with stage III/IV grade C periodontitis: a randomized clinical trial. Paşalı Ç, Emingil G, Yılmaz B, et al. Porphyromonas PubMed ↗
Review Biomolecules · 2025 Oral-Gut Microbial Crosstalk and Therapeutic Applications of Bacterial Extracellular Vesicles. Fu W, Yang N, Yan J, et al. Akkermansia muciniphila PubMed ↗
Observational Microbiome · 2025 Periodontitis salivary microbiota exacerbates colitis by CXCL3 derived from gut microbiota-induced macrophages. Qian J, Tao Q, Shen Y, et al. Escherichia coliLacticaseibacillus rhamnosus PubMed ↗
Meta-analysis Current microbiology · 2025 The Role of the Oral Microbiome in Periodontal Disease: A Systematic Review of Microbial Associations and Therapeutic Implications. Alavi SE, Ebrahimi Shahmabadi H, Sharma LA, et al. FusobacteriumPorphyromonasStaphylococcus PubMed ↗
Randomized trial Clinical oral investigations · 2025 Effects of daily home-use water flossing as an adjunct to non-surgical periodontal therapy in the treatment of stage I-II periodontitis: a 6-month randomized controlled trial. Liu J, Zhou Y, Zhang L, et al. Gemella PubMed ↗
Meta-analysis BMC oral health · 2025 Causal effects of gut microbiota on periodontitis risk: a meta-analysis of Mendelian randomization studies. Yu J, Zuo Y, Yang L, et al. ButyricicoccusGranulicatellaPrevotella PubMed ↗
Observational Scientific reports · 2025 Interaction between serum levels of Porphyromonas gingivalis immunoglobulin G and lutein/zeaxanthin is associated with risk for age-related macular degeneration. Chiu CJ, Chiu ES, Chang ML Porphyromonas PubMed ↗
Review Neuro endocrinology letters · 2025 Periodontitis, Fusobacterium nucleatum, and Colorectal Carcinoma. A Review. Straka M, Borecová P, Straka M FusobacteriumPorphyromonas PubMed ↗
Review International journal of molecular sciences · 2025 Microbial Coaggregation in the Oral Cavity: Molecular Interactions and Current Insights. Oogai Y, Tanaka Y, Nakata M FusobacteriumPorphyromonas PubMed ↗
Review Frontiers in immunology · 2025 Periodontopathic bacteria in rheumatoid arthritis pathogenesis: bridging clinical associations to molecular mechanisms. Guo X, Wang S, Ding J, et al. Porphyromonas PubMed ↗
Observational Journal of clinical periodontology · 2025 Salivary Biomarker Panel That Identifies Periodontitis in Persons With Type 2 Diabetes: A Secondary Analysis of a Cross-Sectional Study. Miller CS, Yan Q, Kirakodu SS, et al. Porphyromonas PubMed ↗
Observational Molecular oral microbiology · 2025 Long Noncoding RNA Malat1 and Neat1 Associated With Dysbiotic Microbiome and Epithelial-Mesenchymal Transition in Periodontitis. Al-Mufti SM, Abdulkareem AA, Chasib NH, et al. Porphyromonas PubMed ↗
Observational BMC oral health · 2025 FimA genotype variants of Porphyromonas gingivalis in periodontal health and disease: a preliminary observational study among the UAE population. Yadadi SS, Sekar P, Mohammed MM, et al. Porphyromonas PubMed ↗
Observational Journal of medical microbiology · 2025 Correlation in the change of gut microbiota with clinical periodontal parameters in grade C periodontitis patients after non-surgical periodontal therapy. Mutafcilar Velioglu E, Arslan U, Kayis SA, et al. Bacteroides PubMed ↗
Randomized trial Oral health & preventive dentistry · 2025 Clinical Effects of Lactobacillus reuteri on Gingival Inflammation and Alveolar Bone Loss in Periodontitis. Lu J, He X, Du T, et al. Limosilactobacillus reuteri PubMed ↗
Observational Journal of dentistry · 2025 Combined quantitative and relative microbiome profiling reveals key salivary bacteriome shifts associated with periodontal health and different stages of periodontitis. He J, Liu Y, Liu H, et al. FusobacteriumHaemophilusPorphyromonasPrevotella +2 more PubMed ↗