Observational Genome medicine · 2026 Maternal-prenatal gut microbiome-systemic metabolome perturbations and TH2-skewed immunity link to offspring gut microbiome disruption and atopic dermatitis susceptibility. Ng DZW, Yap GC, Tay CJX, et al. Akkermansia muciniphilaAlistipes ihumiiKlebsiella pneumoniaeRomboutsia timonensis +1 more PubMed ↗
Systematic review Experimental dermatology · 2026 The Emerging Role of Gut Microbiota in Inflammatory Skin Diseases: A Systematic Review. Malgesini A, Marsiglia MD, Borghi E, et al. Akkermansia muciniphilaFaecalibacterium prausnitziiMediterraneibacter gnavus PubMed ↗
Randomized trial Nutrients · 2025 Effect of Supplementation with a Specific Probiotic (Bifidobacterium bifidum PRL2010) in Pregnancy for the Prevention of Atopic Dermatitis in Children: Preliminary Results of a Randomized Trial. Anania C, Matys V, Marra S, et al. Bifidobacterium bifidum PubMed ↗
Observational The Journal of allergy and clinical immunology · 2024 Developmental trajectories of atopic dermatitis with multiomics approaches in the infant gut: COCOA birth cohort. Lee E, Kim JH, Lee SY, et al. Mediterraneibacter gnavus PubMed ↗
Observational Journal of medicine and life · 2024 Gut microbiota profile and atopic dermatitis in the first year of life. Pantazi AC, Nori W, Kassim MAK, et al. Escherichia coli PubMed ↗
Randomized trial Neonatology · 2024 The Role of Infant Gut Microbiota Modulation by Perinatal Maternal Probiotic Intervention in Atopic Eczema Risk Reduction. Puisto R, Gómez-Gallego C, Collado MC, et al. Bifidobacterium longum PubMed ↗
Meta-analysis Clinical and experimental dermatology · 2023 Effects of probiotic supplementation in adult with atopic dermatitis: a systematic review with meta-analysis. Husein-ElAhmed H, Steinhoff M Ligilactobacillus salivarius PubMed ↗
Observational Medicina · 2023 Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study. Colombo D, Rigoni C, Cantù A, et al. Bifidobacterium animalis PubMed ↗
Randomized trial Pediatric allergy and immunology · 2023 Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old. Komulainen M, Saros L, Vahlberg T, et al. Bifidobacterium animalis PubMed ↗
Randomized trial Clinical and experimental dermatology · 2023 Randomized double-blind placebo-controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and use of corticosteroids in children and adolescents with atopic dermatitis. Feíto-Rodríguez M, Ramírez-Boscà A, Vidal-Asensi S, et al. Bifidobacterium animalisBifidobacterium longum PubMed ↗
Observational BioMed research international · 2022 Gut Microbiome Characteristics in Mothers and Infants According to the Presence of Atopic Dermatitis. Sung M, Choi Y, Park H, et al. Akkermansia muciniphila PubMed ↗
Systematic review Pediatric allergy and immunology · 2021 Comparative effectiveness of probiotic strains on the prevention of pediatric atopic dermatitis: A systematic review and network meta-analysis. Tan-Lim CSC, Esteban-Ipac NAR, Recto MST, et al. Bifidobacterium animalisBifidobacterium longum PubMed ↗
Journal of agricultural and food chemistry · 2026 Early-Life Intervention with Bifidobacterium longum subsp. infantis CCFM1269 Alleviates Atopic Dermatitis in Mice via the Indole-3-Lactic Acid-AHR Signaling Pathway. Huang Z, Zhang Q, Zhao J, et al. Bifidobacterium longum PubMed ↗
Microbiology spectrum · 2026 Gut microbiota contributes to the therapeutic effect of acupuncture in atopic dermatitis. Seo Y, Kim J, Yeom M, et al. Alistipes ihumiiOdoribacter splanchnicus PubMed ↗
Pediatric allergy and immunology · 2026 Salivary OMICS factors associated with atopic dermatitis in early infancy. Alomeir N, Chinchilli E, Terio C, et al. Bifidobacterium breveVeillonella atypica PubMed ↗
The British journal of dermatology · 2026 Associations between early-life exposures and the infant skin microbiome. Broderick C, Poulsen CS, Hjelmsø MH, et al. Streptococcus parasanguinis PubMed ↗
Immunity · 2026 Intestinal dysbiosis exacerbates skin inflammation via microbial metabolite-driven Th2 cell differentiation. Yu L, Peng S, Chen X, et al. Akkermansia muciniphila PubMed ↗
Food & function · 2026 Bifidobacterium breve CCFM1078 alleviates DNFB-induced atopic dermatitis in early-life via AhR activation, Th1/Th2 immune modulation, and gut microbiota regulation. Li Y, Li H, Zhang Q, et al. Bifidobacterium breve PubMed ↗
Asian Pacific journal of allergy and immunology · 2026 Oral administration of Lactobacillus delbrueckii subsp. lactis LDL557 attenuates airway inflammation and changes the gut microbiota in a Der p-sensitized mouse model of allergic asthma. Chen PC, Hsieh MH, Chen WL, et al. Lactobacillus gasseri PubMed ↗
Advanced science · 2026 Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice. Shi Y, He S, Li C, et al. Akkermansia muciniphilaBifidobacterium breve PubMed ↗
Mediators of inflammation · 2026 Genetic Correlations and Causal Relationships Among Allergic Diseases: A Comprehensive Mendelian Randomization Study With Multiomic Mediation Analysis. Zhang PA, Wang JL, Fu SY, et al. Bacteroides intestinalis PubMed ↗
mSystems · 2025 Integrative multi-omics analysis reveals gut-skin axis mechanisms and novel therapeutic target GALE in atopic dermatitis. Cao F, Liu A, Tong J, et al. Lachnospira eligens PubMed ↗
Journal of microbiology and biotechnology · 2025 Strain-Level Differences of Bifidobacterium breve in the Gut Microbiome between Infants with and without Atopic Dermatitis: Insights from Genome Analysis and Immune Assays. Lee I, Kim SH, Lee MJ, et al. Bifidobacterium breve PubMed ↗
Asian Pacific journal of allergy and immunology · 2025 Moonlighting glyceraldehyde-3-phosphate dehydrogenase of Lactobacillus gasseri inhibits keratinocyte apoptosis and skin inflammation in experimental atopic dermatitis. Chen PC, Hsu HY, Liao YC, et al. Lactobacillus gasseri PubMed ↗
NPJ biofilms and microbiomes · 2025 Integrated multi-omics reveals different host crosstalk of atopic dermatitis-enriched Bifidobacterium longum Strains. Seong HJ, Park YM, Kim BS, et al. Bifidobacterium longum[Clostridium] innocuum PubMed ↗
Archives of dermatological research · 2025 Ligilactobacillus salivarius Lac45 inhibits MRSA and suppresses inflammation in human keratinocyte. Klawkla P, Tran HG, Somparn P, et al. Ligilactobacillus salivarius PubMed ↗
Gut microbes · 2025 2'-FL and cross-feeding bifidobacteria reshaped the gut microbiota of infants with atopic dermatitis ex vivo and prevented dermatitis in mice post-microbiota transplantation through retinol metabolism activation. Qi C, Li Z, Tu H, et al. Bifidobacterium bifidumBifidobacterium longum PubMed ↗
Medicine · 2024 Exploring the causal relationship between gut microbiota and atopic dermatitis: A Mendelian randomization study. Li W, Li A Parabacteroides merdaeRoseburia hominis PubMed ↗
Skin research and technology · 2024 Characteristics of gut microbiota and serum metabolism in patients with atopic dermatitis. Zeng Y, Fan N, Gu X, et al. Faecalibacterium prausnitziiSegatella copri PubMed ↗
International immunopharmacology · 2024 Dupilumab therapy improves gut microbiome dysbiosis and tryptophan metabolism in Chinese patients with atopic dermatitis. Yang L, Li D, Sun S, et al. Mediterraneibacter gnavus PubMed ↗
Nutrients · 2024 Probiotic Consortium Confers Synergistic Anti-Inflammatory Effects in Inflammatory Disorders. Lee C, Kim SW, Verma R, et al. Bifidobacterium animalis PubMed ↗
The Australasian journal of dermatology · 2024 Investigating causal relationships between the gut microbiota and inflammatory skin diseases: A Mendelian randomization study. Gu Y, Zhang W, Zhao W, et al. Faecalicatena fissicatena PubMed ↗
Scientific reports · 2024 A novel infant microbiome formula (SIM03) improved eczema severity and quality of life in preschool children. Chan OM, Xu W, Cheng NS, et al. Bifidobacterium bifidumBifidobacterium breve PubMed ↗
mSystems · 2024 Co-occurrence network analysis reveals the alterations of the skin microbiome and metabolome in adults with mild to moderate atopic dermatitis. P Gomes PW, Mannochio-Russo H, Mao J, et al. Streptococcus thermophilus PubMed ↗
Journal of microbiology and biotechnology · 2023 Anti-Inflammatory Response in TNFα/IFNγ-Induced HaCaT Keratinocytes and Probiotic Properties of Lacticaseibacillus rhamnosus MG4644, Lacticaseibacillus paracasei MG4693, and Lactococcus lactis MG5474. Lee JY, Park JY, Jeong Y, et al. Lactococcus lactis PubMed ↗
Molecular nutrition & food research · 2022 Breast Milk-Derived Limosilactobacillus reuteri Prevents Atopic Dermatitis in Mice via Activating Retinol Absorption and Metabolism in Peyer's Patches. Qi C, Tu H, Zhao Y, et al. Akkermansia muciniphilaBacteroides thetaiotaomicron PubMed ↗
Drug design, development and therapy · 2022 Influences of Bifid Triple Viable Capsules Plus Cetirizine on Gut Microbiota and Immune Function in Children with Eczema. Su Z, Kang Y Escherichia coli PubMed ↗
Frontiers in cellular and infection microbiology · 2022 The Difference of Gut Microbiota and Their Correlations With Urinary Organic Acids Between Autistic Children With and Without Atopic Dermatitis. Hong RP, Hou YY, Xu XJ, et al. Akkermansia muciniphilaAnaerobutyricum halliiBifidobacterium bifidumHaemophilus parainfluenzae +1 more PubMed ↗
Immunity, inflammation and disease · 2022 Synbiotic containing extensively hydrolyzed formula improves gastrointestinal and atopic symptom severity, growth, caregiver quality of life, and hospital-related healthcare use in infants with cow's milk allergy. Hubbard GP, Atwal K, Graham L, et al. Bifidobacterium breve PubMed ↗
Experimental dermatology · 2022 Bifidobacterium infantis strain YLGB-1496 possesses excellent antioxidant and skin barrier-enhancing efficacy in vitro. Ma X, Pan Y, Zhao W, et al. Bifidobacterium longum PubMed ↗