Observational Frontiers in cellular and infection microbiology · 2026 Absolute quantification by mouthwash testing screens severe periodontitis and tracks species-specific microbial response to periodontal therapy. Eom JH, Cho MY, Kim JW, et al. Fusobacterium PubMed ↗
Observational Journal of clinical periodontology · 2026 Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression. Manzoor M, Leskelä J, Könönen E, et al. Fusobacterium PubMed ↗
Randomized trial International dental journal · 2026 Short-Term Effects of Comprehensive Periodontal Initial Therapy on Subgingival Microbiota in Nasopharyngeal Carcinoma Patients Undergoing Radiotherapy: A Pilot Randomised Controlled Trial. Lv S, Xu Z, He Q, et al. FusobacteriumHaemophilusPrevotellaVeillonella PubMed ↗
Randomized trial Nature communications · 2026 Oral microbiome modulation mitigates hyperglycemia exacerbation in gestational diabetes mellitus. Gao S, Yin N, Wei R, et al. PrevotellaStreptococcus PubMed ↗
Review Clinical and experimental dental research · 2026 The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis. Afshar Y, Rezaei N Fusobacterium PubMed ↗
Observational Journal of periodontology · 2026 Association between oral microbial diversity and periodontitis in a nationally representative U.S. population: A cross-sectional study. Pu R, Wang Z, Chen Y, et al. Veillonella PubMed ↗
Observational Journal of clinical periodontology · 2026 Stage-Associated Subgingival Dysbiosis Across the Periodontal Disease Spectrum in a Thai Cohort. Sawangpanyangkura T, Suparan K, Wechwithayakhlung C, et al. DialisterOdoribacterPrevotella PubMed ↗
Review Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026 [The Oral Microbiome: Maintenance of Homeostasis, Disease Associations, and Mechanisms of Pathogenesis]. Chen Z, Zhang X FusobacteriumStreptococcus PubMed ↗
Review Frontiers in immunology · 2026 The oral - X axis: from periodontal dysbiosis to systemic disease. Jin W, Tang L, Yang J, et al. Fusobacterium PubMed ↗
Observational Frontiers in cellular and infection microbiology · 2026 Oral microbiome profiles by periodontitis stage in a Korean population. Cho MY, Eom JH, Kim JW, et al. Megasphaera PubMed ↗
Review Microbiological research · 2026 Bacterial extracellular vesicles in the oral-gut axis: Roles in periodontitis and inflammatory bowel disease. He J, Hu H, Huang Y, et al. Akkermansia muciniphila PubMed ↗
Observational Frontiers in endocrinology · 2026 Salivary microbiota signatures of periodontitis are associated with CGM-derived short-term glycaemic control in adults with type 1 diabetes: a pilot study. Munsch K, Sun J, Canceill T, et al. Eubacterium PubMed ↗
Systematic review BMC oral health · 2026 Clinical efficacy of Lactobacillus plantarum and Lactobacillus brevis as adjuncts to professional mechanical plaque removal in periodontitis: a systematic review. Putri RRGA, Sulijaya B, Soeroso Y, et al. Lactiplantibacillus plantarumLevilactobacillus brevis PubMed ↗
Observational Journal of applied microbiology · 2026 Integrative analysis of bacterial diversity in patients with type 2 diabetes mellitus and periodontitis using a case-control microbiome approach. Martínez-Gregorio H, Vallejo-Lecuona F, Ambriz-Barrera F, et al. HaemophilusMegasphaera PubMed ↗
Observational Scientific reports · 2026 Potential biomarkers for early periodontal inflammation: investigating CD5+ B cells, salivary cytokines and oral microbiome. Gottschalk EC, Chabanovska O, Vasudevan P, et al. Megasphaera PubMed ↗
Observational BMC oral health · 2026 Periodontal disease-associated oral and gut microbiome changes in female rheumatoid arthritis patients. Wang X, Long T, Shen L, et al. FusobacteriumPrevotellaStreptococcus PubMed ↗
Observational Scientific reports · 2026 Culturable and unculturable periodontal microorganisms in non-small cell lung cancer: an exploratory analysis. Chamat M, Lafaurie GI, Castillo DM, et al. Eubacterium PubMed ↗
Observational BMC oral health · 2025 Comparative analysis of the microbiota in gingival crevicular fluid from peri-implantitis and periodontitis using 16 S ribosomal RNA gene amplicon sequencing: a cross-sectional study. Liu H, Chen J, Chen Q, et al. FusobacteriumHaemophilusPrevotellaVeillonella PubMed ↗
Review Biomolecules · 2025 Oral-Gut Microbial Crosstalk and Therapeutic Applications of Bacterial Extracellular Vesicles. Fu W, Yang N, Yan J, et al. Akkermansia muciniphila PubMed ↗
Observational Microbiome · 2025 Periodontitis salivary microbiota exacerbates colitis by CXCL3 derived from gut microbiota-induced macrophages. Qian J, Tao Q, Shen Y, et al. Escherichia coliLacticaseibacillus rhamnosus PubMed ↗
Meta-analysis Current microbiology · 2025 The Role of the Oral Microbiome in Periodontal Disease: A Systematic Review of Microbial Associations and Therapeutic Implications. Alavi SE, Ebrahimi Shahmabadi H, Sharma LA, et al. Fusobacterium PubMed ↗
Meta-analysis BMC oral health · 2025 Causal effects of gut microbiota on periodontitis risk: a meta-analysis of Mendelian randomization studies. Yu J, Zuo Y, Yang L, et al. ButyricicoccusPrevotella PubMed ↗
Review Neuro endocrinology letters · 2025 Periodontitis, Fusobacterium nucleatum, and Colorectal Carcinoma. A Review. Straka M, Borecová P, Straka M Fusobacterium PubMed ↗
Review International journal of molecular sciences · 2025 Microbial Coaggregation in the Oral Cavity: Molecular Interactions and Current Insights. Oogai Y, Tanaka Y, Nakata M Fusobacterium PubMed ↗
Observational Journal of medical microbiology · 2025 Correlation in the change of gut microbiota with clinical periodontal parameters in grade C periodontitis patients after non-surgical periodontal therapy. Mutafcilar Velioglu E, Arslan U, Kayis SA, et al. Bacteroides PubMed ↗
Randomized trial Oral health & preventive dentistry · 2025 Clinical Effects of Lactobacillus reuteri on Gingival Inflammation and Alveolar Bone Loss in Periodontitis. Lu J, He X, Du T, et al. Limosilactobacillus reuteri PubMed ↗
Observational Journal of dentistry · 2025 Combined quantitative and relative microbiome profiling reveals key salivary bacteriome shifts associated with periodontal health and different stages of periodontitis. He J, Liu Y, Liu H, et al. FusobacteriumHaemophilusPrevotellaStreptococcus PubMed ↗
Randomized trial Journal of clinical periodontology · 2025 Use of the Probiotic Limosilactobacillus reuteri as an Adjunct to Subgingival Instrumentation in the Treatment of Periodontitis Patients With Diabetes: A Randomised Clinical Trial. Bujaldón R, Montero E, Gamonal JD, et al. Limosilactobacillus reuteri PubMed ↗
Randomized trial Clinical oral investigations · 2025 Clinical and microbiological effectiveness of limosilactobacillus reuteri in supportive periodontal therapy: randomized clinical trial. Mensi M, Scotti E, Marchetti S, et al. Limosilactobacillus reuteri PubMed ↗
Observational Journal of clinical periodontology · 2025 Oral Microbiota Linking Humoral Response, Periodontitis and Atherosclerosis. Akhi R, Lavrinienko A, Hakula M, et al. Prevotella PubMed ↗
Randomized trial BMC oral health · 2025 The impact of Limosilactobacillus reuteri in combination with non-surgical periodontal therapy on periodontal clinical parameters and salivary and subgingival microbiota composition in individuals with stage III-IV periodontitis: a randomized controlled trial. Huo P, Deng L, Lu J, et al. Limosilactobacillus reuteriPrevotella PubMed ↗
Meta-analysis Journal of periodontal research · 2025 The Effect of Non-Surgical Periodontal Therapy on Subgingival Microbiota: A Systematic Review and Meta-Analysis. Krajewski A, Perussolo J, Ercal P, et al. EubacteriumPrevotella PubMed ↗
Observational Clinical oral investigations · 2025 Bacterial translocation signatures and subgingival microbiome in individuals with periodontitis. Britos M, Hernández M, Fernández A, et al. FusobacteriumPrevotella PubMed ↗
Review Frontiers in immunology · 2025 Dental problems and oral microbiome alterations in ulcerative colitis. Kucharski R, Sobocki BK, Stachowska E, et al. Fusobacterium PubMed ↗
Meta-analysis Journal of periodontal research · 2025 Diagnostic Accuracy of Microbiome-Derived Biomarkers in Periodontitis: Systematic Review and Meta-Analysis. Dong A, Proctor G, Zaric S Prevotella PubMed ↗
Observational Journal of oral biosciences · 2024 Oral microbiome profiles of gingivitis and periodontitis by next-generation sequencing among a group of hospital patients in Korea: A cross-sectional study. Lee YH, Park HJ, Jeong SJ, et al. Phocaeicola PubMed ↗
Observational BMC oral health · 2024 Alterations in subgingival microbiome and advanced glycation end-products levels in periodontitis with and without type 1 diabetes mellitus: a cross-sectional study. Chen J, Wang H, Bu S, et al. HaemophilusVeillonella PubMed ↗
Review International journal of molecular sciences · 2024 Oral Pathobiont-Derived Outer Membrane Vesicles in the Oral-Gut Axis. Catalan EA, Seguel-Fuentes E, Fuentes B, et al. Akkermansia muciniphilaFusobacterium PubMed ↗
Observational Translational psychiatry · 2024 Probing the oral-brain connection: oral microbiome patterns in a large community cohort with anxiety, depression, and trauma symptoms, and periodontal outcomes. Malan-Müller S, Vidal R, O'Shea E, et al. Haemophilus parainfluenzae PubMed ↗
Observational Journal of the American Heart Association · 2024 Alterations in the Salivary Microbiome and Metabolism in Patients With Carotid Atherosclerosis from Rural Northeast China. Wu Y, Xing L, Lu L, et al. Megasphaera PubMed ↗
Systematic review European journal of medical research · 2024 Bacteria of healthy periodontal tissues as candidates of probiotics: a systematic review. Del Pilar Angarita-Díaz M, Fong C, Medina D Haemophilus parainfluenzaeActinomycesPrevotellaStreptococcus PubMed ↗
Review Expert opinion on therapeutic patents · 2024 An insight into the last 5-year patents on Porphyromonas gingivalis and Streptococcus mutans, the pivotal pathogens in the oral cavity. Bernardoni BL, D'Agostino I, La Motta C, et al. Streptococcus PubMed ↗
Systematic review Medicina · 2024 Microbiota Transplantation as an Adjunct to Standard Periodontal Treatment in Periodontal Disease: A Systematic Review. Lindo CE, Sebastian J, Kuntjoro KN, et al. Haemophilus parainfluenzaeFusobacteriumPrevotella PubMed ↗
Review Critical reviews in microbiology · 2024 Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecular mechanisms. Mukherjee S, Chopra A, Karmakar S, et al. FusobacteriumHaemophilusVeillonella PubMed ↗
Review Annals of agricultural and environmental medicine · 2024 Relationship between periodontal diseases and non-specific inflammatory bowel diseases - an overview. Part I. Goździewska M, Łyszczarz A, Kaczoruk M, et al. Fusobacterium PubMed ↗
Review Frontiers in immunology · 2024 Oral microbiota-host interaction: the chief culprit of alveolar bone resorption. Xu J, Yu L, Ye S, et al. Fusobacterium PubMed ↗
Observational Alzheimer's research & therapy · 2024 Profiles of subgingival microbiomes and gingival crevicular metabolic signatures in patients with amnestic mild cognitive impairment and Alzheimer's disease. Qiu C, Zhou W, Shen H, et al. Veillonella parvulaActinomycesDialister PubMed ↗
Observational BMC oral health · 2024 Metagenomic analysis of healthy and diseased peri-implant microbiome under different periodontal conditions: a cross-sectional study. Song L, Feng Z, Zhou Q, et al. Prevotella PubMed ↗
Randomized trial Clinical oral investigations · 2024 Effect of adjuvant probiotic therapy (Lactobacillus reuteri) in the treatment of periodontitis associated with diabetes mellitus: clinical, controlled, and randomized study. Jardini MAN, Pedroso JF, Ferreira CL, et al. Limosilactobacillus reuteri PubMed ↗
Meta-analysis Journal of clinical periodontology · 2023 Exploring the causal relationship between periodontitis and gut microbiome: Unveiling the oral-gut and gut-oral axes through bidirectional Mendelian randomization. Chen H, Peng L, Wang Z, et al. AlistipesHoldemanella PubMed ↗