Randomized trial European journal of nutrition · 2026 Impact of brewer's spent grain (BSG) and bio-transformed BSG biscuits on metabolic and gut health in adults with metabolic impairments: a randomized controlled trial. Xu Y, Leong ZN, Huang Y, et al. [Clostridium] scindens PubMed ↗
Observational Clinical rheumatology · 2025 Exploring the gut microbiome in systemic lupus erythematosus: metagenomic and metabolomic insights into a new pro-inflammatory bacteria Clostridium scindens. Wang H, Zhang M, Hua B, et al. [Clostridium] scindensMediterraneibacter gnavus PubMed ↗
Observational Journal of cystic fibrosis · 2025 Fecal microbiota changes in people with cystic fibrosis after 6 months of elexacaftor/tezacaftor/ivacaftor: Findings from the promise study. Duong JT, Hayden HS, Verster AJ, et al. [Clostridium] scindensEscherichia coliMediterraneibacter gnavus PubMed ↗
Review FEMS microbiology reviews · 2025 Clostridium scindens: history and current outlook for a keystone species in the mammalian gut involved in bile acid and steroid metabolism. Daniel SL, Ridlon JM [Clostridium] scindens PubMed ↗
Systematic review Multiple sclerosis and related disorders · 2024 The multiple sclerosis gut microbiome and disease activity: A systematic review. Jette S, de Schaetzen C, Tsai CC, et al. [Clostridium] scindensCollinsella aerofaciensRoseburia inulinivorans PubMed ↗
Review Pathogens · 2024 Interplay between Bile Acids and Intestinal Microbiota: Regulatory Mechanisms and Therapeutic Potential for Infections. Li W, Chen H, Tang J [Clostridium] scindensEscherichia coliStreptococcus thermophilus PubMed ↗
Review Journal of lipid research · 2023 The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology. Ridlon JM, Daniel SL, Gaskins HR [Clostridium] scindens PubMed ↗
Journal for immunotherapy of cancer · 2026 Screening of known gut microbiome-derived metabolites in anti-tumor immunity of colorectal cancer. Zhang X, Li Z, Hua H, et al. [Clostridium] scindens PubMed ↗
Gut microbes · 2026 Pangenome analysis reveals both niche-specific "specialists" and microbial "side hustlers" in colorectal cancer microbiomes. Lee J, Minot S, Dey N [Clostridium] scindensFaecalibacterium prausnitzii PubMed ↗
Journal of bacteriology · 2026 Anaerobic riboflavin degradation by human gut Lachnospiraceae. Quiles Pérez CJ, Olzak A, Fofana A, et al. [Clostridium] scindensFaecalicatena fissicatena PubMed ↗
Gut · 2026 Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer. Osswald A, Wortmann E, Wylensek D, et al. [Clostridium] scindensFaecalicatena contorta PubMed ↗
Biochemistry · 2026 Gut Bacterial 20-Hydroxysteroid Dehydrogenases Modify Endogenous Glucocorticoids and Corticosteroid Drugs. Coyne S, Ghergurovich R, Sacco F, et al. [Clostridium] scindensBifidobacterium adolescentis PubMed ↗
Annals of clinical microbiology and antimicrobials · 2026 Gut microbiome features associated with vancomycin-resistant Enterococcus acquisition in intensive care unit patients. Chuang YC, Collman RG, Ruan SY, et al. [Clostridium] scindens PubMed ↗
The Journal of steroid biochemistry and molecular biology · 2026 Characterization of an NADPH-dependent 17ɑ-hydroxysteroid dehydrogenase encoded by the desF gene from the gut bacterium Clostridium scindens VPI 12708. Wang T, Binion B, Alves JMP, et al. [Clostridium] scindensEggerthella lenta PubMed ↗
Frontiers in cellular and infection microbiology · 2026 SSTDhunter: a curated gene database for investigating androgen producing potential in microbiota species. Wang S, Yang Y, Lei L, et al. [Clostridium] scindens PubMed ↗
mBio · 2025 Gut microbiota dysbiosis and metabolic perturbations of bile/glyceric acids in major depressive disorder with IBS comorbidity. Du J-Y, Zhang Z-J, Tan L, et al. [Clostridium] scindensEggerthella lenta PubMed ↗
CNS neuroscience & therapeutics · 2025 Gut Microbiota-Bile Acid-Brain Axis and TGR5-ERK1/2 Signaling Mediate ADT-Induced Cognitive Impairment. Yang F, Liu Y, Zhou Z, et al. [Clostridium] scindens PubMed ↗
FASEB journal · 2025 Integrated Microbiota-Bile Acid Analysis as Potential NonInvasive Biomarkers for Ulcerative Colitis Staging Diagnose. He T, Wang Y, Zhao L, et al. [Clostridium] scindens[Clostridium] symbiosum PubMed ↗
Nature microbiology · 2025 An expanded metabolic pathway for androgen production by commensal bacteria. Wang T, Ahmad S, Cruz-Lebrón A, et al. [Clostridium] scindens PubMed ↗
EMBO molecular medicine · 2025 Bile acid 7α-dehydroxylating bacteria accelerate injury-induced mucosal healing in the colon. Jalil A, Perino A, Dong Y, et al. [Clostridium] scindens PubMed ↗
Advanced science · 2024 Clostridium Scindens Protects Against Vancomycin-Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR-FGF15/19 Signaling. Xiao J, Hou Y, Luo X, et al. [Clostridium] scindens PubMed ↗
Cell reports · 2024 Gut Bacteroides ovatus ameliorates renal fibrosis by promoting the production of HDCA through upregulation of Clostridium scindens. Si ZL, Wang HY, Wang T, et al. [Clostridium] scindensBacteroides ovatus PubMed ↗
Nature communications · 2024 Elucidating human gut microbiota interactions that robustly inhibit diverse Clostridioides difficile strains across different nutrient landscapes. Sulaiman JE, Thompson J, Qian Y, et al. [Clostridium] scindens PubMed ↗
BMC microbiology · 2024 Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid. Vico-Oton E, Volet C, Jacquemin N, et al. [Clostridium] scindens PubMed ↗
Microbiology spectrum · 2024 A high-dimensional platform for observing neutrophil-parasite interactions. Thompson BA, Revilla J, Brovero S, et al. [Clostridium] scindens PubMed ↗
Nature communications · 2024 Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism. Wahlström A, Brumbaugh A, Sjöland W, et al. [Clostridium] scindens PubMed ↗
Gut microbes · 2024 BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7α-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704. Meibom KL, Marion S, Volet C, et al. [Clostridium] scindens PubMed ↗
American journal of physiology. Gastrointestinal and liver physiology · 2023 Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter. Calton CM, Carothers K, Ramamurthy S, et al. [Clostridium] scindens PubMed ↗
ACS biomaterials science & engineering · 2023 Engineering a Cortisol Sensing Enteric Probiotic. Litteral V, Migliozzi R, Metzger D, et al. [Clostridium] scindens PubMed ↗
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2023 Clostridium scindens metabolites trigger prostate cancer progression through androgen receptor signaling. Bui NN, Li CY, Wang LY, et al. [Clostridium] scindens PubMed ↗
mSystems · 2022 Surgical Treatment for Colorectal Cancer Partially Restores Gut Microbiome and Metabolome Traits. Shiroma H, Shiba S, Erawijantari PP, et al. [Clostridium] scindens PubMed ↗
Frontiers in cellular and infection microbiology · 2021 Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study. Genton L, Lazarevic V, Stojanovic O, et al. [Clostridium] scindensAlistipes communisEnterocloster bolteaePhascolarctobacterium faecium PubMed ↗
Cell discovery · 2026 GV-971 remodels the gut microbiota-bile acid-FXR axis to ameliorate obesity and metabolic dysfunction. Zhang N, Ye X, Wang K, et al. [Clostridium] scindens PubMed ↗
NPJ biofilms and microbiomes · 2026 Maternal cold exposure improves offspring metabolic health via a milk lithocholic acid-microbiota-Th17 axis. Han X, Yu H, Gao Q, et al. [Clostridium] scindens PubMed ↗
iMeta · 2026 Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging. Lin WC, Zhang C, Lei HH, et al. [Clostridium] scindens PubMed ↗
Anaerobe · 2026 Bile acid-mediated inhibition of C. difficile by P. hiranonis revealed through a ΔbaiCD mutant. von Emloh L, Ingle P, Volet C, et al. [Clostridium] scindens PubMed ↗
Clinical rheumatology · 2026 Comment on: "Exploring the gut microbiome in systemic lupus erythematosus: metagenomic and metabolomic insights into a new pro-inflammatory bacteria Clostridium scindens"-a call to disentangle clostridium scindens' bile acid metabolism from glucocorticoid modulation in SLE pathogenesis. Yang M, Fang J, Liao Q [Clostridium] scindens PubMed ↗
Applied and environmental microbiology · 2026 Identification of the C9-hydrogenase for 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid (9,17-DOHNA) and the 7α-dehydratase essential for initiating β-oxidation of the B-, C-, and D-rings in steroid degradation by Comamonas testosteroni TA441. Horinouchi M [Clostridium] scindens PubMed ↗
bioRxiv · 2026 Differential effects of two common GVHD prophylaxis regimens on the gut microbiome: Results from the BMT CTN 1801 study. Wirbel J, Saber W, Martens MJ, et al. [Clostridium] scindens PubMed ↗
bioRxiv · 2026 Anaerobic riboflavin degradation by human gut Lachnospiraceae. Quiles-Pérez CJ, Olzak A, Fofana A, et al. [Clostridium] scindensFaecalicatena fissicatena PubMed ↗
Iranian biomedical journal · 2026 Biotechnological Approaches to Probiotics and Postbiotics through the Gut-Brain Axis Modulation. Firoozi M, Mahdavinezhad A, Shirzad M, et al. [Clostridium] scindensBifidobacterium animalisFaecalibacterium prausnitzii PubMed ↗
bioRxiv · 2025 Characterization of an NADPH-dependent 17α-hydroxysteroid dehydrogenase encoded by the desF gene from the gut bacterium Clostridium scindens VPI 12708. Wang T, Binion B, Alves JMP, et al. [Clostridium] scindens PubMed ↗
Microorganisms · 2025 Pangenome Analysis of Clostridium scindens: A Collection of Diverse Bile Acid- and Steroid-Metabolizing Commensal Gut Bacterial Strains. Olivos-Caicedo KY, Fernandez-Materan FV, Daniel SL, et al. [Clostridium] scindens PubMed ↗
EMBO molecular medicine · 2025 Microbiome-derived secondary bile acids promote repair of colonic mucosa after injury. Attema B, Kuipers F [Clostridium] scindens PubMed ↗
Microbial cell · 2025 Clostridium scindens promotes gallstone formation by inducing intrahepatic neutrophil extracellular traps through CXCL1 produced by colonic epithelial cells. Yao W, He Y, Xie Z, et al. [Clostridium] scindens PubMed ↗
Discover imaging · 2025 Deep learning imaging analysis to identify bacterial metabolic states associated with carcinogen production. Orouskhani M, Rauniyar S, Morella N, et al. [Clostridium] scindens PubMed ↗
Microbiology resource announcements · 2024 Genome sequences of nine Clostridium scindens strains isolated from human feces. Fernandez-Materan FV, Olivos-Caicedo KY, Daniel SL, et al. [Clostridium] scindens PubMed ↗
bioRxiv · 2024 Pangenome analysis of Clostridium scindens : a collection of diverse bile acid and steroid metabolizing commensal gut bacterial strains. Olivos-Caicedo KY, Fernandez F, Daniel SL, et al. [Clostridium] scindens PubMed ↗
Journal of Crohn's & colitis · 2024 Inflammatory bowel disease associated with primary sclerosing cholangitis is associated with an altered gut microbiome and bile acid profile. Leibovitzh H, Nayeri S, Borowski K, et al. [Clostridium] scindensBlautia obeumVeillonella atypicaVeillonella dispar PubMed ↗
JHEP reports · 2024 A gut microbiota-independent mechanism shapes the bile acid pool in mice with MASH. Gillard J, Roumain M, Picalausa C, et al. [Clostridium] scindens PubMed ↗