Systematic review World journal of urology · 2026 Gut microbiome impact on systemic therapy outcomes in metastatic renal cell carcinoma: a systematic review. Gavi F, Bracco M, Testori N, et al. Akkermansia muciniphilaBifidobacterium animalis PubMed ↗
Meta-analysis Urologiia · 2026 [Microbiome as a Novel Player in the Development and Treatment of Renal Cancer: A Systematic Review and Meta-Analysis]. Vorobev V A, Gadzhieva Z K, Malov S I, et al. Akkermansia muciniphila PubMed ↗
Clinical trial Nature medicine · 2026 Fecal microbiota transplantation plus immunotherapy in metastatic renal cell carcinoma: the phase 1 PERFORM trial. Fernandes R, Jabbarizadeh B, Rajeh A, et al. Segatella copri PubMed ↗
Review European urology focus · 2025 Clinical Applications of Microbiome in Renal Cell Carcinoma. Elyas S, Barata P, Vaishampayan U Akkermansia muciniphila PubMed ↗
Animal study Scientific reports · 2023 An oral cancer vaccine using Bifidobacterium vector augments combination of anti-PD-1 and anti-CTLA-4 antibodies in mouse renal cell carcinoma model. Ueki H, Kitagawa K, Kato M, et al. Bifidobacterium longum PubMed ↗
Randomized trial Cancer medicine · 2020 Randomized trial assessing impact of probiotic supplementation on gut microbiome and clinical outcome from targeted therapy in metastatic renal cell carcinoma. Dizman N, Hsu J, Bergerot PG, et al. Akkermansia muciniphilaBarnesiella intestinihominisBifidobacterium animalis PubMed ↗
Observational European urology · 2020 Stool Microbiome Profiling of Patients with Metastatic Renal Cell Carcinoma Receiving Anti-PD-1 Immune Checkpoint Inhibitors. Salgia NJ, Bergerot PG, Maia MC, et al. Akkermansia muciniphila PubMed ↗
European urology · 2020 Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients. Derosa L, Routy B, Fidelle M, et al. Akkermansia muciniphilaHungatella hathewayi PubMed ↗