Clostridium sporogenes
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Its ID gene: the stretch scientists read to tell microbes apart. Each bar is one letter of its DNA. Every species has its own order of letters, so the pattern works like a fingerprint. Close relatives share most of it.
16S rRNA gene, V4 region: the 253 letters between the standard primers (515F/806R), which are the same in every species. One reference sequence; strains can differ by a letter or two. NCBI NR_029231.1
Formerly Metchnikovillus sporogenes.
Large for a gut microbe: longer than 73% of the 2,354 we have genomes for.
28% G+C, higher than 2% of gut microbes.
To scale: if its ID gene were 1 cm long, its genome would stretch 28 meters. Yours would stretch 21 kilometers. One reference genome; strains vary. NCBI GCF_000973705.1
What it can do
- Can make butyrate A short-chain fatty acid that feeds the cells lining the colon.
- Can make propionate A short-chain fatty acid, mostly used by the liver.
- Can make lactic acid What yogurt bacteria make; other microbes turn it into butyrate.
- Can make B vitamins Folate, B12, riboflavin and others.
Not seen in its genomes or lab tests: ferment fiber, eat inulin, eat resistant starch, eat pectin, use lactose, feed on gut mucus, change bile acids, make hydrogen sulfide, make methane.
All 13 capabilities and their evidence
| Capability | Verdict | Genome analysis | Lab tests | Published research |
|---|---|---|---|---|
| Can make butyrate | Can | 2 of 2 genomes | — | No papers |
| Can make propionate | Can | 2 of 2 genomes | — | No papers |
| Can make lactic acid | Can | 2 of 2 genomes | — | No papers |
| Can ferment fiber | Not seen | 0 of 2 genomes | 0 of 9 strains · strip test | No papers |
| Can eat inulin | Not seen | 0 of 2 genomes | 0 of 1 strain · strip test | No papers |
| Can eat resistant starch | Not seen | 0 of 2 genomes | — | No papers |
| Can eat pectin | Not seen | 0 of 2 genomes | — | No papers |
| Can use lactose | Not seen | 0 of 2 genomes | 0 of 6 strains | No papers |
| Can feed on gut mucus | Not seen | 0 of 2 genomes | — | No papers |
| Can change bile acids | Not seen | 0 of 2 genomes | — | No papers |
| Can make B vitamins | Can | 2 of 2 genomes | — | No papers |
| Can make hydrogen sulfide | Not seen | 0 of 2 genomes | — | No papers |
| Can make methane | Not seen | 0 of 2 genomes | — | No papers |
AGORA2 (Heinken et al. 2023) via VMH, CC BY 4.0 · BacDive (DSMZ), CC BY 4.0 · NJC19 (Lim et al., Scientific Data 2020), CC0
In healthy guts
Found in under 1% of healthy people.
- largest Segatella copri 6.2%
- 2nd largest Phocaeicola vulgatus 5.0%
- 3rd largest Faecalibacterium prausnitzii 4.7%
- 4th largest Bacteroides uniformis 3.2%
- 5th largest Agathobacter rectalis 2.5%
- 6th largest Alistipes putredinis 2.3%
- 7th largest Bifidobacterium longum 2.1%
- 8th largest Ruminococcus bromii 1.8%
- Clostridium sporogenes under 0.01%
- 2,169 other microbes, each a sliver 56.7%
- 15.6%
On average, a sliver, under 0.01% of the microbes in a healthy gut.
Every group, drawn the same way. Only some samples record age or sex, so each group says how many people it comes from. Tap one to see it above.